Results 211 to 220 of about 13,572 (283)

Late Toxicity and Long‐Term Quality of Life in Survivors of Cancer of the Major Salivary Glands More Than 5 Years After Diagnosis: A Multi‐National Study

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Because salivary gland cancers (SGC) are rare and include different tumor subtypes, data on their long‐term quality of life and late toxicities are sparse. Methods Multi‐national study including SGC survivors more than 5 years after diagnosis.
Susanne Singer   +26 more
wiley   +1 more source

Safety and Efficacy Findings From a Phase Ib/II Study of ASP‐1929 Photoimmunotherapy With Pembrolizumab in Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma

open access: yesHead &Neck, EarlyView.
ABSTRACT Background ASP‐1929 photoimmunotherapy—cetuximab conjugated to IRDye 700DX and red light (690 nm) for localized drug activation—results in rapid, selective cell killing. Methods This phase Ib/II open‐label study evaluated ASP‐1929 photoimmunotherapy plus pembrolizumab in patients with recurrent/metastatic HNSCC (≥ 1 accessible lesion, PD‐L1 ...
David M. Cognetti   +17 more
wiley   +1 more source

Incidence and temporal trends of depression and anxiety following cancer diagnosis in Japan: Insights from the LIFE study

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Depression and anxiety are common but often under‐recognized among cancer patients. Using claims data from 14 municipalities in Japan, this study clarified the incidence and temporal trends of these conditions following cancer diagnosis over a 24‐month follow‐up period.
Kengo Kawaguchi   +5 more
wiley   +1 more source

Experiences of disrespect and abuse during childbirth in the World Health Organization European region: A mixed‐method study among 22 countries

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Despite advancements in maternity quality care worldwide, mistreatment of women during childbirth persists. Currently, there is a gap of knowledge on the occurrence of disrespect and abuse during childbirth in the World Health Organization (WHO) European region.
Anna Galle   +126 more
wiley   +1 more source

Application of the augmented competing stimulus assessment to identify and establish competing self‐restraint items

open access: yesJournal of Applied Behavior Analysis, EarlyView.
Abstract Automatically maintained self‐injurious behavior (SIB) sometimes co‐occurs with self‐restraint, a self‐limiting behavior that impedes SIB and can be maladaptive (e.g., hinders functional skills and movement). The presence of self‐restraint suggests SIB produces aversive consequences, which self‐restraint limits.
Michelle A. Frank‐Crawford   +5 more
wiley   +1 more source

Quantitative Mapping of Fibrotic Tissue Mechanics via Brillouin Spectroscopy

open access: yesJournal of Biophotonics, EarlyView.
Brillouin spectroscopy distinguishes fibrotic from healthy tissue based on localized stiffness changes and enables real‐time monitoring of dynamic alterations in viscoelastic properties during fibrogenesis. ABSTRACT Fibrosis is a pathological scarring process that disrupts tissue architecture, and is characterized by excessive extracellular matrix (ECM)
Vsevolod Cheburkanov   +3 more
wiley   +1 more source

Evaluation of the Pharmacokinetics, Disposition, and Metabolism of Miricorilant, a Novel Glucocorticoid Receptor Modulator for the Treatment of Metabolic Dysfunction‐Associated Steatohepatitis in Nonclinical and Clinical Studies

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Miricorilant is a novel selective glucocorticoid receptor (GR) modulator with mixed agonist/antagonist effects at the GR and modest antagonism at the mineralocorticoid receptor that is being developed for the treatment of metabolic dysfunction‐associated steatohepatitis.
Hazel J. Hunt   +3 more
wiley   +1 more source

Comparison of Auto‐Contouring Tools for Delineation of Normal Organs at Risk in Paediatric Patients Undergoing Radiotherapy

open access: yesJournal of Medical Radiation Sciences, EarlyView.
Contouring organs at risk (OARs) manually in paediatric patients undergoing cranial‐spinal radiation therapy (CSI) is a time‐consuming, labour‐intensive task. This study aims to assess the accuracy and clinical acceptability of auto‐contours produced by the Siemens DirectORGANS auto‐contouring software on paediatric patients receiving CSI treatment ...
Isabel Cant   +6 more
wiley   +1 more source

Neurofibroma of the Cheek and Nasal Dorsum: A Case Report and a Mini Review

open access: bronze, 2016
Neelam Wadhwa   +4 more
openalex   +1 more source

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