Results 211 to 220 of about 13,825 (328)

Verekitug, a Novel Antibody Antagonist to the TSLP Receptor in Adults with Asthma: A 32‐Week Randomized Phase 1b Multiple Ascending‐Dose Trial

Clinical Pharmacology &Therapeutics, EarlyView.
Verekitug, a novel, high‐affinity, fully human monoclonal antibody targeting thymic stromal lymphopoietin receptor (TSLPR), is in development as a potential treatment for severe asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), and chronic obstructive pulmonary disease (COPD).
Dave Singh, Chaim M. Brickman, Peter Lloyd, Ashish Kalra, Subhabrata Biswas, Arkadeep Sinha, Alex Mulvanny, Sumathi Sivapalasingam, Oren M. Becker, Aaron Deykin   +9 more
wiley   +1 more source

Droplet manipulation enabled by bio‐inspired high‐aspect‐ratio micropumps via mold‐assisted microfabrication

Droplet, EarlyView.
We developed a mold‐assisted microfabrication approach for micro electrohydrodynamic (EHD) pumps. This approach achieved a record‐high aspect ratio of 3.5 and delivered the highest power density with high specific pressure among reported designs. Utilizing this pump, we developed a highly integrated microfluidic chip with unprecedented chip‐to‐pump ...
Zebing Mao, Chao Luo, Yanhong Peng, Yang Li, Yile Chen, Sirui Pan, Junji Ohgi, Weidi Huang, Jianhua Zhang, Bing Xu   +9 more
wiley   +1 more source

Nasal dorsum reconstruction with ear cartilage and retroauricular muscle

, 2018
Basel Al Kadah, Maximilian Linxweiler, Berhard Schick   +2 more
openalex   +1 more source

SEMI-OPEN RHINOPLASTY FOR APPROACHING NASAL TIP AND DORSUM [PDF]

, 2016
N. Y. Abou‐Zeid, Mahmoud El-Fouly, Ahmed Kamel, Basim Wahba, Refaat Bahman, Mohamed Abd Elmottaleb Sabaa   +5 more
openalex   +1 more source

A comprehensive embryonic staging series of the turtle Trachemys scripta

Developmental Dynamics, EarlyView.
Abstract Background Turtles hold a unique place in vertebrate evolutionary history, making them critical assets in embryology research. Yet, they remain understudied as potential model organisms in the field. Here, to support experimental manipulations with turtle embryos, we have created a complete normal table of development for comprehensive ...
Christina M. Noravian, Perla G. Rand, Amira Mahomed, Annie Rickard, Oscar D. Juvera, Maria Elena de Bellard, Max Ezin   +6 more
wiley   +1 more source

Robinow syndrome DVL1 variants disrupt morphogenesis and appendage formation in a Drosophila disease model

Developmental Dynamics, EarlyView.
Abstract Background Robinow syndrome is a rare developmental syndrome caused by variants in genes in Wnt signaling pathways. We previously showed that expression of patient variants in Dishevelled 1 (DVL1) in Drosophila and chicken models disrupts the balance of canonical and non‐canonical Wnt signaling.
Gamze Akarsu, Katja R. MacCharles, Kenneth Kin Lam Wong, Joy M. Richman, Esther M. Verheyen   +4 more
wiley   +1 more source

The bundle of twigs cartilage graft for augmentation of the nasal dorsum

, 2015
Sérgio Moreira da Costa, Gustavo Moreira da Costa Souza, Waldemar Chaves Nascimento Brandão Penna, Lívia Neffa, Rodolfo Guedes Afiune   +4 more
openalex   +1 more source

Heterozygous Med13l mice recapitulate a developmental growth delay and craniofacial anomalies seen in MED13L syndrome

Developmental Dynamics, EarlyView.
Abstract Background Gene transcription is crucial for embryo and postnatal development and is regulated by the Mediator complex. Mediator is comprised of four submodules, including the kinase submodule (CKM). The CKM consists of MED13, MED12, CDK8, and CCNC.
Anna K. Leinheiser, Timothy T. Nguyen, Kayla M. Henry, Mariela Rosales, Eric Van Otterloo, Chad E. Grueter   +5 more
wiley   +1 more source

The role of Rho GTPases in facial morphogenesis

Developmental Dynamics, EarlyView.
The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley   +1 more source

Autogenous auricular concha cartilage transplant in corrective rhinoplasty [PDF]

, 1991
Berghaus, Alexander, Jovanovic, S.
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