Results 51 to 60 of about 365,414 (154)

Evaluating the Local Response of a Novel Injectable Capsule for Drug Delivery in the Trachea

open access: yesThe Laryngoscope, EarlyView.
A novel PLGA polymer capsule was developed for localized pretracheal drug delivery and evaluated for short‐term local tissue safety in a rabbit model. Implant placement was confirmed by ultrasound and was well tolerated over 14 days, with preservation of airway patency, native tracheal architecture, and biomechanical properties.
Denzel Ryan D. Cruz   +7 more
wiley   +1 more source

Evaluation of the effect of levocetirizine on nasal mucociliary clearance in allergic rhinitis patients by rhinoscintigraphy

open access: yes, 2007
Objective The purpose of this study was to assess the effect of levocetirizine on nasal mucociliary clearance in allergic rhinitis patients using ...
Sutbeyaz, Yavuz   +3 more
core   +1 more source

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

open access: yesMed Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu   +9 more
wiley   +1 more source

EFFECT OF NASOTRACHEAL INTUBATION ON NASAL MUCOCILIARY CLEARANCE

open access: yesBritish Journal of Anaesthesia, 1987
Forty patients were studied to investigate the effect of nasotracheal intubation on nasal mucociliary clearance measured with the radiopaque disc method under standard conditions. Postoperative mucociliary slowing on the intubated side was observed in 65% of patients. Difficult or prolonged intubation increased the incidence of mucociliary stasis. Age,
S, Elwany, A, Mekhamer
openaire   +2 more sources

Prediction of nasal spray drug absorption influenced by mucociliary clearance.

open access: yesPLoS ONE, 2021
Evaluation of nasal spray drug absorption has been challenging because deposited particles are consistently transported away by mucociliary clearance during diffusing through the mucus layer.
Yidan Shang   +5 more
doaj   +1 more source

In situ gels as a modern method of intranasal vaccine delivery

open access: yesВопросы вирусологии, 2022
The continuous emergence of new pathogens and the evolution of microbial drug resistance make it absolutely necessary to develop innovative, effective vaccination strategies. Use of nasal vaccination can increase convenience, safety, cause both local and
Elena O. Bakhrushina   +4 more
doaj   +1 more source

Association of Nasal Anatomy, Airflow, and Surgery With Olfactory Outcomes: A State‐of‐the‐Art Review

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Olfactory function is influenced by nasal airflow dynamics and anatomical variations within the nasal cavity. This narrative review evaluates how nasal anatomy and airflow relate to olfactory outcomes, with a particular focus on olfactory changes following functional nasal surgery. Data Sources PubMed.
Joshua Ferreira   +3 more
wiley   +1 more source

Acute and long-term management of severe bronchiectasis with high flow nasal therapy: A case report

open access: yesMonaldi Archives for Chest Disease, 2022
Bronchiectasis (BE) is a long-term, chronic lung condition featured by widened and scarred airways. These can alter the physiological mucociliary clearance, making it difficult to clear mucus and microorganisms, leading to frequent exacerbations.
Pietro Impellizzeri   +7 more
doaj   +1 more source

Clinical Management and Outcomes of Neonatal Rhinitis Nasal Obstruction: A Scoping Review

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Neonatal rhinitis represents an underdiagnosed yet potentially serious condition in newborns. Standardized diagnostic and treatment protocols remain lacking. The objective is to review the current literature on the etiology, diagnosis, and management of neonatal rhinitis in infants ≤8 months of age.
Anthony Victor, Mathieu Bergeron
wiley   +1 more source

Radiofrequency Thermal Ablation versus Bipolar Electrocautery for the Treatment of Inferior Turbinate Hypertrophy: Comparison of Efficacy and Postoperative Morbidity

open access: yesInternational Archives of Otorhinolaryngology, 2016
Introduction Numerous surgical methods are used to treat nasal obstruction due to inferior turbinate hypertrophy. The primary goal of the therapy is to maximize the nasal airway for as extended a period of time as possible while minimizing therapeutic ...
Sinan Uluyol   +6 more
doaj   +1 more source

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