Results 111 to 120 of about 346,071 (293)

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum   +5 more
wiley   +1 more source

Bone: The final frontier for penetration in chronic rhinosinusitis

open access: yesJournal of Otolaryngology - Head and Neck Surgery, 2013
The superantigenic properties of Staphylococcus aureus have been implicated in increasing the inflammatory process in airway diseases. Local formation of IgE antibodies against staphylococcal enterotoxins by secondary lymphoid tissue in nasal polyps has ...
Rogério Pezato   +5 more
doaj   +1 more source

Survey of Otolaryngologists on Delayed Epistaxis Following Posterior Nasal Nerve Ablation

open access: yes
International Forum of Allergy &Rhinology, EarlyView.
Jacob Schwartz   +2 more
wiley   +1 more source

Overcoming intranasal delivery barriers with ultrastable polyzwitterionic siRNA nanocages for enhanced glioblastoma therapy

open access: yesBMEMat, EarlyView.
A ROS‐responsive, zwitterionic nanocage enables stable, intranasal siRNA delivery to glioblastoma, promoting deep tumor penetration via non‐degradative pathways and trigeminal nerve transport. This platform achieves durable gene silencing and tumor suppression, offering a non‐invasive, storage‐stable strategy for treating glioma and other neurological ...
Jingwen Xie   +12 more
wiley   +1 more source

Anatomy of the Soft Palate and Its Role in Upper Airway Function: A Narrative Review

open access: yesClinical Anatomy, EarlyView.
ABSTRACT The soft palate is a complex anatomical structure, located at the posterior aspect of the oral and nasal cavities, able to dynamically create valve closure of the nasal and the oral cavities. Its precise movement is critical for speech, swallowing, and respiration. Despite its functional importance, detailed characterization of its constituent
James C. D. Miller   +4 more
wiley   +1 more source

Mudanças na mucosa nasal por exposição à fumaça por electrocoagulação

open access: yes, 2016
Objective: to prove that exposure to smoke resulting from electrocoagulation causes changes in the nasal mucosa of physicians in training at a public hospital in Mexico.
Aldrete, María G.   +3 more
core   +2 more sources

Developmental Morphometry of the Paranasal Sinuses in Subjects Aged 1–25 Years: A Computed Tomography Study

open access: yesClinical Anatomy, EarlyView.
ABSTRACT The present study aimed to evaluate the developmental morphometry of the paranasal sinuses using computed tomography (CT) in subjects aged 1–25 years and to characterize age‐related changes in sinus dimensions, volume, and surface area throughout childhood, adolescence, and young adulthood.
Ceyda Şevval Çetin   +4 more
wiley   +1 more source

Beta-adrenergic mechanisms in the nasal mucosa vascular bed.

open access: yes, 1995
In thiopentone-anesthetized mature pigs (n = 7), local intra-arterial infusion of the beta 2-adrenoceptor agonists terbutaline and salbutamol and the beta 3-agonist BRL 37344 induced dose-dependent increases in nasal arterial blood flow (BF) and volume ...
Lacroix JS   +3 more
core   +1 more source

Implant‐related orofacial pain managed with implant apicoectomy: A case report

open access: yesClinical Advances in Periodontics, EarlyView.
Abstract Background In recent years, the use of implants has emerged as a widely accepted method for the replacement of missing teeth. Although rare, chronic pain associated with implant placement has been reported in the literature. Conversely, apicoectomy, the removal of the apical portion has been integrated into the implantology field in cases with
Oscar Durán‐Garnica   +4 more
wiley   +1 more source

Bimanual instrument suturing technique for periodontal and implant microsurgery: A technical note

open access: yesClinical Advances in Periodontics, EarlyView.
Abstract Background In the traditional suturing technique, the dominant hand (DH) holds a needle holder, and the non‐dominant hand (NH) performs manual ties without the aid of an instrument. In periodontal and implant microsurgery, finer sutures and needles, e.g., 7‐0 in International Organization for Standardization units, are used, which could be ...
Mark Gordon   +5 more
wiley   +1 more source

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