Results 121 to 130 of about 83,352 (300)

Region‐Resolved Proteomics Identifies Molecular Features at the Mucosa‐Polyp Interface in Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
Yi‐Sook Kim, Hong‐Beom Park, Roza Khalmuratova, Hyun Kyung Lee, Doo Hee Han, Dae Woo Kim, Dohyun Han, Hyun‐Woo Shin   +7 more
wiley   +1 more source

Overcoming intranasal delivery barriers with ultrastable polyzwitterionic siRNA nanocages for enhanced glioblastoma therapy

BMEMat, EarlyView.
A ROS‐responsive, zwitterionic nanocage enables stable, intranasal siRNA delivery to glioblastoma, promoting deep tumor penetration via non‐degradative pathways and trigeminal nerve transport. This platform achieves durable gene silencing and tumor suppression, offering a non‐invasive, storage‐stable strategy for treating glioma and other neurological ...
Jingwen Xie, Jingxing Si, Xiaobei Deng, Jing Tan, Ruijie Zhu, Jizhou Qi, Gaoxia Ma, Bin Wang, Yi Wang, Yunzhou Guo, Yuping Chen, Shiqun Shao, Youqing Shen   +12 more
wiley   +1 more source

The effect of macrolides on allergic rhinitis versus chronic rhinosinusitis- an in-vitro study

, 2009
PhDBackground The mechanisms of the rhinitic process are complex. Previous studies upon nasal epithelial cells have begun to investigate rhinitis.
Kuchai, Romana
core  

Implant‐related orofacial pain managed with implant apicoectomy: A case report

Clinical Advances in Periodontics, EarlyView.
Abstract Background In recent years, the use of implants has emerged as a widely accepted method for the replacement of missing teeth. Although rare, chronic pain associated with implant placement has been reported in the literature. Conversely, apicoectomy, the removal of the apical portion has been integrated into the implantology field in cases with
Oscar Durán‐Garnica, Karen Villarreal‐Arizpe, Hong Chen, Hsun‐Liang Chan, Guo‐Liang Cheng   +4 more
wiley   +1 more source

Astaxanthin ameliorates allergic rhinitis via suppression of the HMGB1/TLR4 signaling pathway

Central European Journal of Immunology
Background Allergic rhinitis (AR) is a common inflammatory disease of the nasal mucosa mediated by immunoglobulin E (IgE). Astaxanthin (AST) has been demonstrated to attenuate airway inflammation in an asthmatic mouse model.
Xixi Lei, Jun Pan, Kebin Deng
doaj   +1 more source

FOXP3+ CD4+ T cells in the steady-state nasal mucosa display a memory phenotype.

, 2016
(A) Samples of enzymatically digested nasal mucosa contained readily identifiable and viable CD3+ T cells. Representative plots showing the gating strategy when comparing the CD45RO-expression on CD4+ T cells derived from PBMCs or released from nasal ...
Espen S. Baekkevold (417844), Frode L. Jahnsen (850017), Christina Ballke (850015), Einar Gran (850016)   +3 more
core   +1 more source

Novel Organelle‐Based Intracellular Immunity With Mechanistic and Therapeutic Implications

Barrier Immunity, EarlyView.
A conceptual framework illustrating how PAMPs/DAMPs initiate barrier, innate, adaptive, and intracellular immune responses, with organelle‐based intracellular immunity serving as a central integrator linking metabolism, inflammatory signaling, and therapeutic interventions to restore immune homeostasis.
Keman Xu, Shih‐Yu Hung, Fatma Saaoud, Ying Shao, Yifan Lu, Juanjuan Liu, Bo Yuan, Haiyan Xiang, Hong Wang, Xiaofeng Yang   +9 more
wiley   +1 more source

Vimentin Expression in Nasal Mucosa of Patients with Exacerbated Chronic Rhinosinusitis Without Nasal Polyps

, 2019
Objective. The aim of the study was to evaluate vimentin expression in inflamed nasal mucosa of patients with chronic rhinosinusitis without nasal polyps (CRSsNP) and serum levels of matrix metalloproteinase-9 (MMP-9)
Tkachenko A. S., Gubina-Vakulyck G. I., Tkachenko V. L., Nakonechna O. A., Kalashnyk I. M., Onishchenko A. I.   +5 more
core   +1 more source

Increased interval between seizure clusters across time in pediatric patients treated with the immediate‐use seizure medication diazepam nasal spray

Epilepsia, EarlyView.
Abstract Objective Seizure clusters, intermittent increases in seizure activity that differ from a patient's usual seizure pattern, may occur despite treatment with a daily anti‐seizure medication. Benzodiazepine‐containing immediate‐use seizure medications (ISMs; also called rescue therapies) are the cornerstone of treatment for seizure clusters ...
James W. Wheless, Eric Segal, Jurriaan M. Peters, Steven M. Wolf, Genei Bougher, Charles Davis, Leock Y. Ngo, Enrique Carrazana, Adrian L. Rabinowicz   +8 more
wiley   +1 more source

Lipid‐based Nano‐delivery systems as a promising strategy for the treatment of epilepsy: Current status and challenges

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy is a prevalent chronic neurological disorder characterized by abnormal neuronal electrical activity. The primary treatment modality for individuals with epilepsy (PWE) is antiseizure medication (ASM). The multiple potential factors contributing to treatment resistance in epilepsy may be attributed to the inability of ASMs to
Priya Kannan Varshini, Arunachalam Divya, Kumar Sowndharya, Parthiban Jeevitha, Selvam Manoj, Ashiq Rahman, Athil Ahamed, Ravichandiran Abirahul, Paranthaman Subash, Sulekha Khute   +9 more
wiley   +1 more source