Results 121 to 130 of about 602,823 (332)

3D bioprinting in oral and craniomaxillofacial tissue regeneration: Progress, challenges, and future directions

BMEMat, EarlyView.
This paper summarized the application of 3D bioprinting in the regeneration of various tissues in the oral and craniomaxillofacial fields, including the required biomaterials and printing techniques. Abstract Oral and craniomaxillofacial tissues are essential for maintaining oral functions, including respiration, mastication, swallowing, and speech ...
Huilu Zhan, Haohao Ni, Xingge Yu, Mazaher Gholipourmalekabadi, Tianqi Wang, Kaili Lin, Jinsong Pan, Changyong Yuan   +7 more
wiley   +1 more source

Crestal approach for repair of oroantral bone defects and subsequent implant placement

Clinical Advances in Periodontics, EarlyView.
Abstract Background Oroantral communication (OAC) can occur after a dental extraction. Occasionally, bony defects may persist despite successful soft tissue closure of the OAC. The absence of bone in these areas poses challenges for dental implant placement.
Min Yang, Miriam Ting, Rodrigo Neiva, Jonathan Korostoff   +3 more
wiley   +1 more source

INDICATORS OF MUC 5AC AND MUC 1 MUCOPOLYSACCHARIDE EXPRESSION IN THE NASAL MUCOSA OF PATIENTS WITH POSTNASAL DRIP SYNDROME AND NASAL SEPTUM DEVIATION

Клінічна та профілактична медицина
Introduction. Determining the cause of postnasal drip syndrome can be quite challenging. Nasal septum deformation has been recognized as one possible factor.
Nataliia V. Babchenko, Yulia V. Dieieva, Serhii E. Konovalov, Oleksii V. Motailo   +3 more
doaj   +1 more source

Citrus Flavonoids for Cystic Fibrosis Treatment

ChemBioChem, EarlyView.
Studies conducted since the late 1990s show substantial activity of selected citrus flavonoids as cystic fibrosis transmembrane conductance regulator (CFTR) membrane protein activators. The thesis of this work is that aptly formulated citrus flavonoids hold sigificant potential for developing a multitarget treatment of cystic fibrosis combining in a ...
Mario Pagliaro, Caterina Di Sano, Claudia D'Anna, Giovanna Li Petri, Giuseppe Angellotti, Rosaria Ciriminna   +5 more
wiley   +1 more source

Evolving Real‐World Data and Evidence Use for New Drugs and Regenerative Medical Products Approvals in Japan—An Analysis of the 6‐Year Trend

Clinical Pharmacology &Therapeutics, EarlyView.
Several regulatory initiatives have been made to clarify the acceptability and requirements of real‐world data and real‐world evidence (RWD/E) for the benefit/risk assessment of new medical products in Japan. The objectives of this review were to characterize the use of RWD/E in regulatory applications of new medical products and to describe the ...
Suguru Okami, Kako Shimotsumagari, Yasunari Sadatsuki   +2 more
wiley   +1 more source

Research on the Distribution Law of Air Flow and Dust in Multi‐Process Operations of Coal Mine Fully Mechanized Caving Face

Energy Science &Engineering, EarlyView.
ABSTRACT The aim of this study is to examine the intricate dynamics involved in the production, movement, and settling of dust particles, as well as the interconnected mechanisms at play during various processes within fully automated coal mining fronts.
Yibo Li, Xiangjun Chen, Yunfei Du, Lin Li, Peiqi Zuo, Mengke Liu   +5 more
wiley   +1 more source

Extracellular Vesicle‐Based mRNA Therapeutics and Vaccines

Exploration, EarlyView.
This review provides a comprehensive analysis of recent advancements in extracellular vesicle (EV)‐based messenger RNA (mRNA) applications for therapeutics and vaccines. It systematically outlines strategies for mRNA encapsulation within EVs and elucidates the challenges associated with this technology, offering insights into future research directions
Qi Li, Haonan Xing, Abid Naeem, Kaiyue Zhang, Aiping Zheng, Yuanyu Huang, Mei Lu   +6 more
wiley   +1 more source

Anti‐Inflammatory Effects of Flavonoids in Otitis Media: A Systematic Review of Pre‐Clinical Evidence

Food Frontiers, EarlyView.
Otitis media (OM) is a middle ear infection driven by chronic inflammation, leading to tissue damage and complications such as cholesteatoma. Flavonoids, a class of polyphenols with anti‐inflammatory properties, suppress key inflammatory mediators, reducing neutrophilic infiltration and mucosal thickening. These findings suggest flavonoids as potential
Madiha Ajaz, Ayesha Zahid, Hazrat Ismail, Misbah Ajaz   +3 more
wiley   +1 more source

Emerging Frontiers in Food Allergy Treatment: Progress, Challenges, and Prospects

Food Frontiers, EarlyView.
Food allergy is a rising global health concern with limited treatment options beyond allergen avoidance and emergency care. This review explores the evolving therapeutic landscape, highlighting advances in allergen immunotherapy, biologics such as monoclonal antibodies, and emerging vaccine‐based approaches.
Ayesha Zahid, Hazrat Ismail, Madiha Ajaz, Abdul Qadeer   +3 more
wiley   +1 more source

Magnifying Glass on Sinonasal NUT Carcinoma Heterogeneity via Spatial Transcriptomics

Head &Neck, EarlyView.
ABSTRACT Background Nuclear protein in testis (NUT) carcinomas (NCs) are rare, clinically aggressive tumors with characteristic translocation involving NUTM1 and BRD4 genes. While NCs are generally characterized by undifferentiated basaloid cells with focal/abrupt squamous differentiation, tumoral heterogeneity remains unexplored.
Diana Bell, Garret Choby, Michelle Afkhami, Ellie Maghami, Renata Ferrarotto, Carl Snyderman, Eric Wang, Ehab Hanna, Raja Seethala   +8 more
wiley   +1 more source