Results 201 to 210 of about 133,855 (244)

Management of Vocal Fold Leukoplakia

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Vocal fold leukoplakia (VFL) is a descriptive term for a white plaque in the true vocal folds (TVF). It is estimated at 10.2 cases per 100,000 males and 2.1 per 100,000 females. The most critical aspect of managing a VLF is achieving an accurate pathological diagnosis, since a white plaque in the TVF can have numerous differential diagnoses ...
Isabela H. Schettini, Thomas L. Carroll
wiley   +1 more source

Clinical Presentation, Diagnostic Approaches, and Management of Tornwaldt Cysts: A Comprehensive Narrative Review

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective This narrative review aims to provide otolaryngologists with a comprehensive overview of the clinical presentation, diagnostic approaches, and management strategies for Tornwaldt cysts, synthesizing insights from the available literature.
Antonino Maniaci, Mario Lentini, Salvatore Cocuzza, Jerome Rene Lechien, Francois Simon, Alberto Maria Saibene, Nicolien Van Der Poel, Piero Pavone   +7 more
wiley   +1 more source

[Effects of PM_2.5 and O₃ sub-chronic combined exposure on ATP amount and ATPase activities in rat nasal mucosa]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Yan T, Xu J, Chen T, Yang X, Wang W, Zhou S, Niu P, Jia G, Xia J.   +8 more
europepmc   +1 more source

Naloxone dosing in the era of synthetic opioids: Applying the Goldilocks principle

Addiction, EarlyView.
Abstract The opioid overdose epidemic remains a critical public health crisis. In recent years, synthetic opioids like fentanyl and nitazenes, have driven a sharp rise in deaths. Naloxone, an opioid receptor antagonist, has been established as a key intervention for reversing opioid overdoses and saving lives.
Mariana Gonzalez Utrilla, Edward Chesney, Joanne Neale, Nicola Metrebian, Nicola Kalk, Arne Kristian Skulberg, Paul Dietze, Martin Smith, John Strang   +8 more
wiley   +1 more source

Aggressive Neoplasms That Mimic Chronic Endodontic Lesions: A Multi‐Institutional Case Series

Australian Endodontic Journal, EarlyView.
ABSTRACT This study aimed to report sociodemographic, clinicopathologic and radiological features of 12 cases of aggressive neoplasms that were clinically diagnosed as chronic endodontic lesions. The series comprised seven females (58.33%) and five males (41.67%), with a mean age of 48.9 ± 19.19 years (range: 16–75 years).
Natália Gonçalves Macedo, Fernanda Geraldo Pappen, Bernardo da Fonseca Orcina, Gustavo Mascarenhas, Jean Nunes dos Santos, Paulo Sérgio da Silva Santos, Carolina Clasen Vieira, Alexandre Simões Garcia, Alini Cardoso Soares, Lauren Frenzel Schuch, Ana Paula Neutzling Gomes, Ana Carolina Uchoa Vasconcelos   +11 more
wiley   +1 more source

Rituximab for the Management of an Australian Cohort of Treatment Refractory Mucous Membrane Pemphigoid

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Background Mucous membrane pemphigoid (MMP) has a broad range of clinical manifestations, from relatively benign self‐limiting oral lesions to significant scarring (cicatrizing) of the oral, nasal and ocular tissues with severe functional impairment and morbidity.
Bronte Jeffrey, Mark Schifter, Elizabeth Arena, Emily Sullivan, Stephanie Rose, David Joo, David Campbell, Suzanne Culican, David McDonald, Ming Wei Lin   +9 more
wiley   +1 more source

Transcriptomic Profiles of the Nasal Mucosa Following Birch Pollen Provocation Differ Between Birch Pollen‐Allergic and Non‐Allergic Individuals

Allergy, EarlyView.
Fourteen genes, mainly encoding keratins, were commonly differentially expressed in both allergic and non‐allergic individuals after nasal provocation with birch pollen. The nasal provocation in birch pollen‐allergic individuals led to activation of innate immune pathways within 15–30 min and proliferation‐regulatory pathways within 60–120 min.
Srinidhi Sudharson, Julia Eckl‐Dorna, Anastasia Meshcheryakova, José Basílio, Sophia Derdak, Tanja Kalic, Nina Lengger, Nina Schweitzer, Diana Mechtcheriakova, Heimo Breiteneder, Christine Hafner   +10 more
wiley   +1 more source

The Role of IgE in Crohn's Disease by Impairing the Capacity of Plasmacytoid Dendritic Cells to Generate FOXP3+ Tregs

Allergy, EarlyView.
We uncover an unprecedented role for IgE in CD. CD patients, regardless of allergic status and similar to allergic patients, display higher levels of circulating IgE+ and FcεRI+ immune cells, including pDCs, which are concomitant to fewer Tregs. In vitro experiments show that the anti‐IgE monoclonal antibody omalizumab restores the ability of pDCs from
Andrés de la Rocha‐Muñoz, Cristina Benito‐Villalvilla, David Olivares, Sofía Sirvent, Miguel A. García‐Brenes, Alba Angelina, Leticia Martín‐Cruz, Javier Cuesta, Paolo Tassinari, Xavier Jaumont, Carlos Taxonera, Oscar Palomares   +11 more
wiley   +1 more source

Dupilumab Treatment Is Associated With Clinical Improvement and a Shift Toward a Health‐Associated Nasal Passage Microbiota in Diffuse Type 2 Chronic Rhinosinusitis

Allergy, EarlyView.
This study investigates longitudinal effects of dupilumab on the nasal passage and gastrointestinal microbiota in patients with diffuse type 2 CRSwNP. CRSwNP patients show altered nasal microbiota composition compared to healthy individuals. Dupilumab treatment is associated with a shift of nasal microbiota in CRSwNP, with increasing beneficial genera (
Fabio S. Ryser, Tomas Demeter, Judith Bergada Pijuan, Srikanth Mairpady Shambat, Catrin Brühlmann, Tina Mauthe, Markus Hilty, Michael B. Soyka, Urs C. Steiner, Silvio D. Brugger   +9 more
wiley   +1 more source

Spontaneous Intestinal Perforation in Extremely Premature Infants Exposed to Early Low‐Dose Hydrocortisone

Acta Paediatrica, EarlyView.
ABSTRACT Aim To assess the occurrence of spontaneous intestinal perforation (SIP) in < 28 weeks' gestational age (GA) infants exposed to early low‐dose hydrocortisone (ELH) to reduce the risk of bronchopulmonary dysplasia (BPD). Additionally, the risk of SIP was assessed in infants exposed to early concomitant treatment with ibuprofen for persistent ...
Gilles Cambonie, Anais Jouffrey, Benoit Tessier, Clémentine Combes, Angelo Polito, Arthur Gavotto   +5 more
wiley   +1 more source