Results 41 to 50 of about 602,823 (332)

Nasal Delivery of High Molecular Weight Drugs

Molecules, 2009
Nasal drug delivery may be used for either local or systemic effects. Low molecular weight drugs with are rapidly absorbed through nasal mucosa. The main reasons for this are the high permeability, fairly wide absorption area, porous and thin endothelial
Erdal Cevher, Yıldız Ozsoy, Sevgi Gungor   +2 more
doaj   +1 more source

The frequencies of different types of nasal septum deviation and their effect on increasing the thickness of maxillary sinus mucosa

Journal of Dental Research, Dental Clinics, Dental Prospects, 2019
Background. Diseases of the paranasal sinuses are very prevalent in East Azerbaijan Province, Iran, which is attributed to various reasons, including environmental and anatomical factors. This study investigated the prevalence of anatomical variations of
Hamid Taghiloo, Zohreh Halimi
semanticscholar   +1 more source

Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2 specific CD8 T cell responses following COVID-19

medRxiv, 2021
The immune system plays a major role in Coronavirus Disease 2019 (COVID-19) pathogenesis, viral clearance and protection against re-infection. Immune cell dynamics during COVID-19 have been extensively documented in peripheral blood, but remain elusive ...
A. Roukens, Marion H. König, Tim J. Dalebout, T. Tak, Shohreh Azimi, Y. Kruize, C. R. Pothast, R. Hagedoorn, S. Arbous, Jaimie L. H. Zhang, M. Verheij, C. Prins, A. M. van der Does, P. S. Hiemstra, J. J. D. de Vries, J. Janse, M. Roestenberg, Sebenzile K. Myeni, M. Kikkert, M. Heemskerk, M. Yazdanbakhsh, H. Smits, S. Jochems   +22 more
semanticscholar   +2 more sources

Symbiotic microbiome Staphylococcus epidermidis restricts IL-33 production in allergic nasal epithelium via limiting the cellular necroptosis

BMC Microbiology, 2023
Background Allergic rhinitis (AR) is characterized by airway inflammation in nasal mucosa from inhaled allergens and interleukin (IL)-33 is the potent inducer of Th2 inflammation in allergic nasal epithelium. Staphylococcus epidermidis is one of the most
Yung Jin Jeon, Chan Hee Gil, Jina Won, Ara Jo, Hyun Jik Kim   +4 more
doaj   +1 more source

Interleukin-22 regulates antimicrobial peptide expression and keratinocyte differentiation to control Staphylococcus aureus colonization of the nasal mucosa

Mucosal Immunology, 2016
The local immune response occurring during Staphylococcus aureus nasal colonization remains ill-defined. Studies have highlighted the importance of T-cell immunity in controlling S. aureus colonization of the nasal mucosa.
M. Mulcahy, J. Leech, J. Renauld, K. Mills, R. McLoughlin   +4 more
semanticscholar   +1 more source

Occupational Argyria of the Nasal Mucosa [PDF]

Head and Neck Pathology, 2017
A biopsy specimen from the nasal mucosa of a 37-year-old man disclosed a subepithelial accumulation of black granules mainly running parallel to the surface in the absence of any inflammatory infiltrate. Since the mucosal pigment was negative with Perls' stain and resisted to melanin bleach, an exogenous pigmentation was suspected.
Gerardo Ferrara, Alessandra Filosa, Maria Paola Mariani, Luigi Fasanella   +3 more
openaire   +3 more sources

Local Immunoglobulin E in the Nasal Mucosa: Clinical Implications

Allergy Asthma and Immunology Research, 2015
Immunoglobulin E (IgE) can be highly elevated in the airway mucosa independently of IgE serum levels and atopic status. Mostly, systemic markers are assessed to investigate inflammation in airway disease for research or clinical practice. A more accurate
E. De Schryver, L. Devuyst, L. Derycke, M. Dullaers, T. Van Zele, C. Bachert, P. Gevaert   +6 more
semanticscholar   +1 more source

Use of nasal mucosa graft in tympanoplasty

Brazilian Journal of Otorhinolaryngology, 2022
Tympanoplasty techniques with different types of graft have been used to close tympanic perforations since the 19th century. Tragal cartilage and temporalis fascia are the most frequently used types of graft. They lead to similar functional and morphological results in most cases.
Sandro Barros Coelho, Willian da Silva Lopes, Gabriela de Andrade Meireles Bezerra, Davi Farias de Araújo, Adriano Sérgio Freire Meira, Sílvio da Silva Caldas Neto   +5 more
openaire   +5 more sources

Cold bubble humidification of low-flow oxygen does not prevent acute changes in inflammation and oxidative stress at nasal mucosa

Scientific Reports, 2021
Some clinical situations require the use of oxygen therapy for a few hours without hypoxemia. However, there are no literature reports on the effects of acute oxygen therapy on the nasal mucosa.
Lauriana Alves Santana, Suellen Karoline Moreira Bezerra, Beatriz Mangueira Saraiva-Romanholo, Wellington Pereira Yamaguti, Iolanda de Fátima Lopes Calvo Tibério, Tabata Maruyama dos Santos, Renato Fraga Righetti   +6 more
doaj   +1 more source

Dexamethasone Suppresses Histamine Synthesis by Repressing both Transcription and Activity of HDC in Allergic Rats

Allergology International, 2006
Background: Histamine synthesized by histidine decarboxylase (HDC) from L-histidine is a major chemical mediator in the development of nasal allergy which is characterized by nasal hypersensitivity. However the regulatory mechanism of histamine synthesis
Yoshiaki Kitamura, Asish K Das, Yuki Murata, Kazutaka Maeyama, Shrabanti Dev, Yousuke Wakayama, Bukasa Kalubi, Noriaki Takeda, Hiroyuki Fukui   +8 more
doaj   +1 more source