Results 41 to 50 of about 688,047 (369)

Nasal symbiont Staphylococcus epidermidis restricts the cellular entry of influenza virus into the nasal epithelium

npj Biofilms and Microbiomes, 2022
Our recent study presented that human nasal commensal Staphylococcus epidermidis could potentiate antiviral immunity in the nasal mucosa through interferon-related innate responses. Here, we found that human nasal commensal S.
Ara Jo, Jina Won, Chan Hee Gil, Su Keun Kim, Kang-Mu Lee, Sang Sun Yoon, Hyun Jik Kim   +6 more
doaj   +1 more source

Effects of intranasal administration with Bacillus subtilis on immune cells in the nasal mucosa and tonsils of piglets

Experimental and Therapeutic Medicine, 2018
The nasal mucosa is the body's first barrier against pathogens entering through the respiratory tract. The respiratory immune system of pigs has more similarities with humans than the mouse respiratory system does, and so was selected as the animal model
Yunhan Yang, Yuchao Jing, Jingjing Yang, Qian Yang   +3 more
semanticscholar   +1 more source

Tailoring Formulations for Intranasal Nose-to-Brain Delivery: A Review on Architecture, Physico-Chemical Characteristics and Mucociliary Clearance of the Nasal Olfactory Mucosa

Pharmaceutics, 2018
The blood-brain barrier and the blood-cerebrospinal fluid barrier are major obstacles in central nervous system (CNS) drug delivery, since they block most molecules from entering the brain.
Stella Gänger, K. Schindowski
semanticscholar   +1 more source

Alpha-synuclein seeds in olfactory mucosa of patients with isolated REM sleep behaviour disorder.

Brain : a journal of neurology, 2021
Isolated REM sleep behaviour disorder (RBD) is an early-stage α-synucleinopathy in most, if not all, affected subjects. Detection of pathological α-synuclein in peripheral tissues of patients with isolated RBD may identify those progressing to Parkinson ...
A. Stefani, Á. Iranzo, E. Holzknecht, D. Perra, M. Bongianni, C. Gaig, B. Heim, M. Serradell, Luca Sacchetto, Alicia Garrido, S. Capaldi, A. Sánchez-Gómez, M. P. Cecchini, S. Mariotto, S. Ferrari, M. Fiorini, J. Schmutzhard, P. Cocchiara, I. Vilaseca, Lorenzo Brozzetti, S. Monaco, M. José Martí, K. Seppi, E. Tolosa, J. Santamaria, B. Högl, W. Poewe, G. Zanusso   +27 more
semanticscholar   +1 more source

Drug delivery in overcoming the blood-brain barrier: role of nasal mucosal grafting [PDF]

, 2017
The blood–brain barrier (BBB) plays a fundamental role in protecting and maintaining the homeostasis of the brain. For this reason, drug delivery to the brain is much more difficult than that to other compartments of the body. In order to bypass or cross
Carafa, Maria, Di Marzio, Luisa, Hanieh, PATRIZIA NADIA, Marianecci, Carlotta, Paolino, Donatella, Rinaldi, Federica   +5 more
core   +1 more source

The frequencies of different types of nasal septum deviation and their effect on increasing the thickness of maxillary sinus mucosa

Journal of Dental Research, Dental Clinics, Dental Prospects, 2019
Background. Diseases of the paranasal sinuses are very prevalent in East Azerbaijan Province, Iran, which is attributed to various reasons, including environmental and anatomical factors. This study investigated the prevalence of anatomical variations of
Hamid Taghiloo, Zohreh Halimi
semanticscholar   +1 more source

A reassortant H9N2 influenza virus containing 2009 pandemic H1N1 internal-protein genes acquired enhanced pig-to-pig transmission after serial passages in swine [PDF]

, 2017
Avian H9N2 and 2009 pandemic H1N1 (pH1N1) influenza viruses can infect pigs and humans, raising the concern that H9N2: pH1N1 reassortant viruses could emerge.
Ma, Wenjun, Mancera Gracia, José Carlos, Richt, Juergen A, Saelens, Xavier, Van den Hoecke, Silvie, Van Reeth, Kristien   +5 more
core   +2 more sources

Influence of Immune Status on the Airborne Colonization of Piglets with Methicillin-Resistant Staphylococcus aureus (MRSA) Clonal Complex (CC) 398 [PDF]

, 2020
Colonized vertebrates including humans and pigs are to date the main reservoirs of livestock-associated Methicillin-resistant Staphylococcus aureus (LA-MRSA). Currently, the mechanisms underlying colonization of pigs are not fully understood.
Ebner, Friederike, Friese, Anika, Hartmann, Susanne, Merle, Roswitha, Roesler, Uwe, Rosen, Kerstin, Schmidt, Stefanie   +6 more
core   +1 more source

An alternative pathway of enteric PEDV dissemination from nasal cavity to intestinal mucosa in swine

Nature Communications, 2018
Porcine epidemic diarrhea virus (PEDV) has catastrophic impacts on the global pig industry. Although the fecal–oral route is generally accepted, an increased number of reports indicate that airborne transmission may contribute to PEDV outbreak.
Yuchen Li, Qingxin Wu, Lulu Huang, Chen Yuan, Jialu Wang, Qian Yang   +5 more
semanticscholar   +1 more source

Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2 specific CD8 T cell responses following COVID-19

medRxiv, 2021
The immune system plays a major role in Coronavirus Disease 2019 (COVID-19) pathogenesis, viral clearance and protection against re-infection. Immune cell dynamics during COVID-19 have been extensively documented in peripheral blood, but remain elusive ...
A. Roukens, Marion H. König, Tim J. Dalebout, T. Tak, Shohreh Azimi, Y. Kruize, C. R. Pothast, R. Hagedoorn, Sesmu M. Arbous, Jaimie L. H. Zhang, M. Verheij, C. Prins, A. M. van der Does, P. S. Hiemstra, J. J. D. de Vries, J. Janse, M. Roestenberg, Sebenzile K. Myeni, M. Kikkert, M. Heemskerk, M. Yazdanbakhsh, H. Smits, S. Jochems   +22 more
semanticscholar   +2 more sources