Results 111 to 120 of about 9,405 (123)
ABSTRACT Background There is limited consensus on management protocols and practice patterns following endoscopic skull base surgery (ESBS). Methods An online‐based survey focusing on ESBS practice patterns was anonymously distributed to the American Rhinologic Society, North American Skull Base Society, and American Head and Neck Society Skull Base ...
Khodayar Goshtasbi+15 more
wiley +1 more source
Aggressive Head and Neck Squamous Cell Carcinoma in the Setting of GATA2 Deficiency
ABSTRACT Background GATA2 deficiency is a rare genetic disorder associated with hematologic, infectious, and neoplastic complications. We report a case of a patient with GATA2 deficiency who developed aggressive squamous cell carcinoma (SCC) of the head and neck, an atypical manifestation of this condition.
Brejjette Aljabi+3 more
wiley +1 more source
ABSTRACT Background Adenoid cystic carcinoma (ACC) is an aggressive therapy‐resistant head and neck cancer with a high frequency of local recurrences and distant metastases. Activation of the MYB gene, encoding an oncogenic master transcription factor, is the key genomic hallmark of ACC and a potential therapeutic target. Here, we have investigated the
Fredrik Jäwert+5 more
wiley +1 more source
Vision Changes After Head and Neck Cancer Treatment
ABSTRACT Background Literature about ocular toxicity after head and neck cancer (HNC) treatment is scarce. This study aimed to describe visual function and ocular symptoms among HNC patients. Methods The study used a cross‐sectional design. Two surveys, The National Eye Institute Visual Functioning Questionnaire (NEI‐VFQ) and an Ocular Symptom Scale ...
Hsiao‐Lan Wang+7 more
wiley +1 more source
ABSTRACT Background This exploratory study investigated tracheoesophageal voicing following 6 weeks of resistance‐based dysphagia rehabilitation with the SEA2.0, using a multidimensional assessment approach. Methods Twenty laryngectomized participants were assessed at T0 (baseline), T1 (after 6 weeks training), and T2 (after 8 weeks rest).
Marise Neijman+7 more
wiley +1 more source
Mechanisms of enhancer‐driven oncogene activation
Abstract An aggressive subtype of acute myeloid leukemia (AML) is caused by enhancer hijacking resulting in MECOM overexpression. Several chromosomal rearrangements can lead to this: the most common (inv(3)/t(3;3)) results in a hijacked GATA2 enhancer, and there are several atypical MECOM rearrangements involving enhancers from other hematopoietic ...
Joyce Vriend+2 more
wiley +1 more source
Enhancer‐dependent gene regulation in space, time, and malignancies
Abstract Control of cell‐type‐specific gene activation requires the coordinated activity of distal regulatory elements, including enhancers, whose inputs must be temporally integrated. Dysregulation of this regulatory capacity, such as aberrant usage of enhancers, can result in malignant transformation of cells.
Belinda Blum+2 more
wiley +1 more source
Global prevalence and risk factors of obstetric violence: A systematic review and meta‐analysis
Abstract Background Obstetric violence (OBV), defined as mistreatment or abuse during childbirth, is a pervasive global issue, albeit with regional differences, affecting women's physical and emotional well‐being. Objectives The purpose of this systematic review and meta‐analysis is to assess the prevalence of OBV to identify risk factors associated ...
Sevil Hakimi+7 more
wiley +1 more source
Recent Advancements in Microfluidic Biosensors for Clinical Applications
The combination of low‐consumption microfluidic chips and high‐sensitivity biosensors enables rapid and accurate detection of complex target analytes. This integrated system holds significant potential for applications in disease diagnosis, health monitoring, and treatment management.
Haiyan Wang, Wenjuan Wu
wiley +1 more source
We printed various 3D conductive microdome geometries using a single direct printing method. Hierarchical dome structures provide linear and sensitive pressure sensing. We applied the hierarchical dome‐structured pressure sensor to a robotic finger, demonstrating its effectiveness in shine muscat harvesting, fine needle sensing, and droplet control ...
Seung Hwan Jeon+14 more
wiley +1 more source