Pathogenesis of chronic rhinosinusitis with nasal polyp and a prominent T2 endotype [PDF]
Chronic rhinosinusitis is a heterogenous and multifactorial disease, characterized by persistent inflammation of the nose and paranasal sinuses, which causes nasal obstruction, nasal discharge, facial pain, and smell disturbance.
Said Ahmad Shāh, Masayoshi Kobayashi
exaly +5 more sources
Effect of prostaglandin D2 on VEGF release by nasal polyp fibroblasts [PDF]
Background: Vascular endothelial growth factor (VEGF) is known to be associated with the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP). VEGF is produced by a variety of cells including fibroblasts.
Ryotaro Omichi +2 more
exaly +5 more sources
Leishmaniasis is an infectious disease caused by a protozoon of the genus Leishmania. It can manifest as cutaneous, mucosal, localized lymphadenitis forms or it can result as multiorgan involvement. In this article we present the case of a 59-year-old male with a polypoid mass attached to the septum at the right nasal cavity and symptoms as nasal ...
Filipello F +5 more
europepmc +3 more sources
Herpes simplex virus type 1 infection facilitates invasion of Staphylococcus aureus into the nasal mucosa and nasal polyp tissue. [PDF]
BACKGROUND: Staphylococcus aureus (S. aureus) plays an important role in the pathogenesis of severe chronic airway disease, such as nasal polyps. However the mechanisms underlying the initiation of damage and/or invasion of the nasal mucosa by S.
XiangDong Wang +9 more
doaj +3 more sources
Predictive significance of Charcot‐Leyden crystal structures for nasal polyp recurrence [PDF]
Background Charcot‐Leyden crystals (CLCs) are recognized to be classic hallmarks of eosinophilic inflammation. Both protein and mRNA levels of CLC in nasal secretions and nasal brushing samples have been associated with nasal polyp recurrence.
Wenyi Chen +11 more
doaj +2 more sources
Clinical profile of nasal polyp in a pediatric patient: An Ayurvedic approach
Nasal polyp is a chronic inflammatory disease affecting the nasal cavity and the paranasal sinuses. It is a relatively common disease occurring in 1%–4% of the general population, but it is also seen in the pediatric population.
Aziz Ahmed Arbar, Sweta Verma
doaj +2 more sources
Distinct Effects of Biological Treatments on Eosinophils and Neutrophils in Chronic Rhinosinusitis With Nasal Polyp Patients [PDF]
Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is generally characterized by tissue‐infiltrating eosinophils. Various biologic treatments, targeting the inflammation, have demonstrated efficacy in reducing nasal polyp size and symptoms ...
Sharon VanNevel +10 more
doaj +2 more sources
Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) is often comorbid with asthma and resistant to therapeutic interventions. We recently reported that excessive fibrin deposition caused by impairment of fibrinolysis might play pivotal role in ...
Tetsuji Takabayashi +8 more
doaj +2 more sources
A Case of Choanal Polyp Originating From the Superior Nasal Concha
Almost all nasal polyps orginate from the mucosa of the lateral walls of the nasal cavity or from the paranasal sinuses. Diagnosis of a choanal polyp is made by endoscopic and radiologic examinations.
Mehmet Kelles +3 more
doaj +2 more sources
Nasal Leishmaniasis Misdiagnosed With Intranasal Polyp in a Patient Candidate for Rhinoplasty
Mucosal leishmaniasis (ML) is a chronic and rare form of leishmaniasis that causes malignant lesions in the mucosa of the nasal, pharyngeal, and laryngeal regions.
Zakaria Zakariaei +5 more
doaj +2 more sources

