Results 11 to 20 of about 22,108 (285)
Effect of prostaglandin D2 on VEGF release by nasal polyp fibroblasts
Background: Vascular endothelial growth factor (VEGF) is known to be associated with the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP). VEGF is produced by a variety of cells including fibroblasts.
Kengo Kanai +8 more
doaj +3 more sources
Herpes simplex virus type 1 infection facilitates invasion of Staphylococcus aureus into the nasal mucosa and nasal polyp tissue. [PDF]
BACKGROUND: Staphylococcus aureus (S. aureus) plays an important role in the pathogenesis of severe chronic airway disease, such as nasal polyps. However the mechanisms underlying the initiation of damage and/or invasion of the nasal mucosa by S.
XiangDong Wang +9 more
doaj +1 more source
Background: Sino-nasal polyps can be treated medically (with systemic and local steroids) or surgically; but a lot of patients refuse surgical intervention or are contraindicated to use systemic steroids. Intra-polyp steroid injections have recently been
Nehad Hassan Abdelrahman +3 more
doaj +1 more source
VISUALIZE: a 24-week, open-label study using nasal endoscopy video to evaluate the efficacy and safety of EDS-FLU 186 μg twice daily in adults with bilateral nasal polyps [PDF]
Background: In prior phase 3, randomized, placebo-controlled trials, fluticasone propionate exhalation delivery system (EDSFLU) over 24 weeks showed significant reduction in total polyp score compared with EDS-placebo.
William C. Yao +3 more
doaj +1 more source
Background: The chemokine receptor, CC-chemokine receptor 3 (CCR3), and its major ligands, eotaxin, RANTES, and MCP-4, are involved in eosinophil chemotaxis. It is thought that CCR3 plays an important role in the recruitment and activation of eosinophils
Hidekazu Saito +4 more
doaj +1 more source
EOSINOPHILS PROFILE AND LUND-MACKAY SCORE OF NASAL POLYPS IN ARIFIN ACHMAD HOSPITAL, RIAU PROVINCE
: Theories suggest that nasal polyps occur as a result of chronic inflammation of the nasal and sinus mucosa. Eosinophils are the main inflammatory cells found in nasal polyp tissue.
Yolazenia Yolazenia +4 more
doaj +1 more source
Optimum imaging for inverted papilloma [PDF]
Inverted papilloma is the most common benign tumour of the nose and paranasal sinuses, and usually arises in the lateral wall of the nasal cavity and the middle meatus.
Howard, D, Lloyd, G, Lund, VJ, Savy, L
core +1 more source
Sphenochoanal polyp causing obstruction
Nasal polyps are mostly referred to as antrochoanal polyps. Polyp arising from sphenoid sinus as such is a rare entity. Radiological investigations include a CT scan of paranasal sinuses and diagnostic nasal endoscopy will confirm the diagnosis. Once the
Shashikant Anil Pol +3 more
doaj +1 more source
A Case of Sinochoanal Polyp Originating From the Ethmoid Sinus [PDF]
A nasal polyp is a distinct mucosal pathology that obstructs the nasal cavity and paranasal sinuses, with various phenotypes and endotypes. Nasal polyps should be distinguished from inverted papillomas, squamous cell carcinomas, juvenile angiofibromas ...
Byung Hun Kim +4 more
doaj +1 more source
Biologics for the treatment of chronic rhinosinusitis with nasal polyps : state of the art [PDF]
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a complex upper airway disease affecting up to 11% of the population of Western Europe. In these western countries, 85% of the CRSwNP disease reveals a type 2 inflammatory pattern. In the last 15 years,
Bachert, Claus +3 more
core +1 more source

