Results 41 to 50 of about 15,953 (256)

Uncovering Cystic Fibrosis Carrier: Insights From a Heterozygous CFTR‐F508del Rabbit Model

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) is a heterogeneous inflammatory disorder frequently associated with impaired mucociliary clearance and bacterial infection. Individuals carrying a single cystic fibrosis transmembrane conductance regulator (CFTR) mutation exhibit partial CFTR dysfunction and are increasingly recognized as being at risk ...
Do‐Yeon Cho, Alexis E. McFeely, Daniel Skinner, Shaoyan Zhang, Justin Hedvat, Weslee Ping‐ay, Daniel M. Beswick, Justin H. Turner, Bradford A. Woodworth, Jie Xu   +9 more
wiley   +1 more source

Association Between the Expression of Cytochrome P450 and Glutathione S-transferase Enzyme and Antrochoanal Polyp Pathogenesis

International Archives of Otorhinolaryngology
Introduction Antrochoanal polyp, which is a kind of smooth-surfaced single nasal polyp, is commonly present in cases of nasal obstruction. The pathogenesis of polyp formation is still unclear, but allergy is supposed to be a cause.
Mehmet Gökhan Demir, Sedat Aydın, Serpil Oguztuzun, Kayhan Basak   +3 more
doaj   +1 more source

Transcriptome Analysis Identifies Doublesex and Mab-3 Related Transcription Factor (DMRT3) in Nasal Polyp Epithelial Cells of Patients Suffering from Non-Steroidal Anti-Inflammatory Drug-Exacerbated Respiratory Disease (AERD)

Biomolecules, 2021
Background: Aspirin-exacerbated respiratory disease (AERD) is a syndrome characterised by chronic rhinosinusitis, nasal polyps, asthma and aspirin intolerance. An imbalance of eicosanoid metabolism with anover-production of cysteinyl leukotrienes (CysLTs)
V.S. Priyadharshini, Marcos Alejandro Jiménez-Chobillon, Jos de Graaf, Raúl Porras Gutiérrez de Velasco, Christina Gratziou, Fernando Ramírez-Jiménez, Luis M. Teran   +6 more
doaj   +1 more source

Allergic Rhinitis Amplifies Asthma Risk in Patients With Chronic Rhinosinusitis: A Large‐Scale Retrospective Cohort Analysis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) and allergic rhinitis (AR) are two highly prevalent airway diseases in the United States. While the coexistence of CRS and asthma is well recognized, less is known about the development of new‐onset asthma in CRS, particularly in the context of comorbid AR. This study assessed the impact of CRS and AR on
Austin J. Lee, Mohamad R. Chaaban
wiley   +1 more source

Nasal polyps in children

Turkish Archives of Otorhinolaryngology, 2007
Objectives: Nasal polyps in the children are uncommon and its etiology is unclear. The purpose of this study is evaluation the alternatives of treatment, histopathological and clinical features of nasal polyposis which in pediatric population, in the ...
Turgut Karlıdağ, Erol Keleş, Cengiz Alpay, Şinasi Yalçın, Ayça Tazegül   +4 more
doaj   +1 more source

Enhanced susceptibility of nasal polyp tissues to avian and human influenza viruses. [PDF]

PLoS ONE, 2010
BACKGROUND: Influenza viruses bind and infect respiratory epithelial cells through sialic acid on cell surface. Differential preference to sialic acid types contributes to host- and tissue-tropism of avian and seasonal influenza viruses.
Ornpreya Suptawiwat, Pongsakorn Tantilipikorn, Chompunuch Boonarkart, Jate Lumyongsatien, Mongkol Uiprasertkul, Pilaipan Puthavathana, Prasert Auewarakul   +6 more
doaj   +1 more source

Oral and Nasal Steroids for Nasal Polyps [PDF]

Current Allergy and Asthma Reports, 2011
Trial: Vaidyanathan S, Barnes M, Williamson P, et al.: Treatment of chronic rhinosinusitis with nasal polyposis with oral steroids followed by topical steroids: a randomized trial. Ann Intern Med 2011; 154:293–302. Rating: •Of importance. Introduction: Chronic rhinosinusitis (CRS) with nasal polyps is a common form of the disorder with distinct ...
openaire   +2 more sources

Biofilm Exoproteins From Staphylococcus Species Impede Re‐Epithelialization of Nasal Epithelial Cells During Wound Healing and Cease Ciliary Beat Frequency

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Introduction Chronic rhinosinusitis (CRS) is an inflammatory disease with many different contributing factors, including bacterial infection. CRS patients are typically managed with medical therapies; however, these treatments frequently fail, leaving surgery as the only viable option.
Sintayehu Ambachew, Mahnaz Ramezanpour, Clare M. Cooksley, Emma F. Barry, Lindsay Durr, Kevin Aaron Fenix, P. J. Wormald, Alkis J. Psaltis, Sarah Vreugde   +8 more
wiley   +1 more source

Evidence for interleukin-5 in nasal polyps in aspirin-induced asthma

Allergology International, 1997
Aspirin-induced asthma is often accompanied by nasal polyps, in which tissue eosinophils are abundant and activated. However, the mechanism of eosinophil infiltration remains unknown.
Norihisa Ogata, Keisuke Masuyama, Makoto Yoshida, Hidetoshi Asai, Muchun Wang, Yasuhiro Samejima, Masao Eura, Noriaki Tsunoda, Takeru Ishikawa   +8 more
doaj   +1 more source

Interspecies Biofilm Dynamics Among Staphylococci: Inflammatory Contributions to Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Introduction Staphylococcus species are frequently isolated from the sinonasal niche of chronic rhinosinusitis (CRS) patients. While Staphylococcus aureus is often associated with recalcitrant CRS, Staphylococcus epidermidis and Staphylococcus lugdunensis are largely deemed commensal.
Sintayehu Ambachew, Mahnaz Ramezanpour, Clare M. Cooksley, Sholeh Feizi, Muhammed Awad, Kevin Aaron Fenix, Peter‐John Wormald, Alkis J. Psaltis, Sarah Vreugde   +8 more
wiley   +1 more source