Results 51 to 60 of about 15,953 (256)

Temperature‐Controlled Radiofrequency for Severe Nasal Airway Obstruction: A Non‐Inferiority Comparison With Surgical Intervention

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Introduction Temperature‐controlled radiofrequency (TCRF), septoplasty (ST) with turbinate reduction, and functional rhinoplasty (FR) are treatment options for nasal airway obstruction (NAO) and nasal valve dysfunction (NVD), but no direct comparison of these procedures has been performed. Methods This prospective, open‐label, non‐inferiority (
Greg Davis, Zeeshan Aziz, Jose Barrera, William Blythe, Chris Davis, Steven Davis, Thomas Higgins, Charles Lano, Gregory Levitin, Frederick Lopatin, Samuel Oyer, Stacey Silvers, Ariel Waitzman, Randall Ow   +13 more
wiley   +1 more source

Synergistic Induction of Macrophage Inflammatory Protein-3α/CCL20 Production by Interleukin-17A and Tumor Necrosis Factor-αin Nasal Polyp Fibroblasts

World Allergy Organization Journal, 2009
Background: Accumulation of T cells and immature dendritic cells (DCs) is one of the characteristic features of nasal polyps. However, the question remains why these cells accumulate in nasal polyp tissue. Macrophage inflammatory protein-3α (MIP-3α/CCL20)
Manabu Nonaka, MD, PhD, Nozomu Ogihara, MD, Akira Fukumoto, MD, PhD, Atsuko Sakanushi, MD, Kaoru Kusama, MD, Ruby Pawankar, MD, PhD, Toshiaki Yagi, MD, PhD   +6 more
doaj   +1 more source

Extent of Sinus Surgery Is Associated With Disease Control in Biologic Treated Type 2 Dominant CRS

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background A greater benefit of biologics is observed after surgery in Type 2 chronic rhinosinusitis with nasal polyps (CRSwNP). However, the extent of surgery remains undefined in many studies. This study evaluated the extent of surgery on disease control in patients receiving biologics for refractory Type 2 dominant CRSwNP.
Nicholas J. Campion, Peta‐Lee Sacks, Lu Hui Png, Ruoxin Hua, Rhea Darbari Kaul, Raquel Alvarado, Christine Choy, Raymond Sacks, Peter Earls, Raewyn G. Campbell, Larry Kalish, Richard J. Harvey   +11 more
wiley   +1 more source

Leptin May Promote Eosinophilic CRSwNP Progression by Enhancing Eosinophil Chemotaxis and Angiogenesis Under a Type 2 Inflammatory Milieu

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda, Yohei Sato, Yoshimasa Imoto, Mayumi Tamari, Shigeharu Fujieda   +4 more
wiley   +1 more source

Female‐Specific Risk of TAS2R Variants in Chronic Rhinosinusitis: A Hospital‐Based Cohort Study From the Taiwan Precision Medicine Initiative

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Bitter taste receptors (T2Rs) function in the innate immune defense of the sinonasal mucosa; however, the genetic association between the TAS2R gene family and chronic rhinosinusitis (CRS) remains understudied in Asian populations.
Rong‐San Jiang, Man‐Wei Hua, I‐Chieh Chen, Yi‐Ming Chen, Shun‐Hung Lin, Kuan‐Yu Lai, Yi‐Chen Chen   +6 more
wiley   +1 more source

Dexamethasone Induces Apoptosis of Nasal Polyp-Derived Tissue Cultures Through JNK and p38 MAPK Activation [PDF]

Clinical and Experimental Otorhinolaryngology, 2014
ObjectivesGlucocorticoids, such as dexamethasone (DEX), increase apoptosis in a variety of white cells in nasal polyps and apoptosis is an important factor in the resolution of inflammation.
Tae-Hoon Lee, Jung Gwon Nam, Ho Min Lee, Bo-Young Kim, Myung-Koo Kang, Woo Yong Bae, Dae Young Hur, Seong Kook Park   +7 more
doaj   +1 more source

Assessing Surgical Extent in Endoscopic Sinus Surgery: A Scoping Review of Scoring Systems

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Endoscopic sinus surgery (ESS) varies substantially in the extent of surgical dissection performed, even when described under the same procedural label. In chronic rhinosinusitis, this heterogeneity may influence postoperative outcomes, revision rates, and response to biologic therapies.
Alexander Lein, Marie T. Ehrgott, Linda Liu, Archana Jaiswal, Rajiv K. Bhalla, Noel Ayoub, Faris F. Brkic, David T. Liu   +7 more
wiley   +1 more source

The Role of Platelet-Derived Growth Factor in the Pathogenesis of Sinonasal Polyps: Immunohistochemical Assessment in Epithelial, Subepithelial and Deep Layers of the Mucosa [PDF]

Clinical and Experimental Otorhinolaryngology, 2013
ObjectivesThe aim of this study is to investigate the role of platelet-derived growth factor (PDGF) in the pathogenesis of sinonasal polyps.MethodsStudy group (groups 1-3) consisted of nasal polyp samples of patients with sinonasal polyps and the control
Nuray Bayar Muluk, Osman Kürşat Arıkan, Pınar Atasoy, Rahmi Kılıç, Eda Tuna Yalçinozan   +4 more
doaj   +1 more source

Concordant systemic and local eosinophilia relates to poorer disease control in patients with nasal polyps

World Allergy Organization Journal, 2019
Background: Eosinophilic inflammation is a major phenotype associated with poorly controlled disease in nasal polyp patients. The difference between systemic and local eosinophilia in relation to disease control is poorly understood.
Kanghua Wang, Jie Deng, Meng Yang, Yang Chen, Fenghong Chen, Wen-Xiang Gao, Yinyan Lai, Jianbo Shi, Yueqi Sun   +8 more
doaj   +1 more source

Gaze Mapping and Observational Behavior During Nasal Endoscopy

International Forum of Allergy &Rhinology, EarlyView.
William S. Smithee, Duncan G. J. Green, Quinn F. O'Malley, Arjun Yusufji, Jonathan M. Owens, Edward D. McCoul   +5 more
wiley   +1 more source