Results 51 to 60 of about 176,283 (284)

Leptin May Promote Eosinophilic CRSwNP Progression by Enhancing Eosinophil Chemotaxis and Angiogenesis Under a Type 2 Inflammatory Milieu

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda, Yohei Sato, Yoshimasa Imoto, Mayumi Tamari, Shigeharu Fujieda   +4 more
wiley   +1 more source

Role of endoscopic surgery in management of nasal polyps [PDF]

Al Ameen Journal of Medical Sciences, 2013
Aims: The aims of the present study were to identify the type and origin of the nasal polyps, to accomplish complete removal of the nasal polyps and to establish natural drainage of the sinuses. Methods and Material: A prospective study on 44 fresh cases
Kiran A. Deshmukh, Pallavi K. Deshmukh, Yatiraj Singi, V.S. Patil, Shivaji S.Patil   +4 more
doaj  

Expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 in recurrent chronic rhinosinusitis with nasal polyposis

Kaohsiung Journal of Medical Sciences, 2013
Matrix metalloproteinase (MMP) is involved in the upper airway remodeling process. We hypothesized that MMP had an additive effect on the formation of recurrent nasal polyp.
Ling-Feng Wang, Chen-Yu Chien, Feng-Yu Chiang, Chee-Yin Chai, Chih-Feng Tai   +4 more
doaj   +1 more source

Female‐Specific Risk of TAS2R Variants in Chronic Rhinosinusitis: A Hospital‐Based Cohort Study From the Taiwan Precision Medicine Initiative

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Bitter taste receptors (T2Rs) function in the innate immune defense of the sinonasal mucosa; however, the genetic association between the TAS2R gene family and chronic rhinosinusitis (CRS) remains understudied in Asian populations.
Rong‐San Jiang, Man‐Wei Hua, I‐Chieh Chen, Yi‐Ming Chen, Shun‐Hung Lin, Kuan‐Yu Lai, Yi‐Chen Chen   +6 more
wiley   +1 more source

Tezepelumab in Chinese Patients With Severe Chronic Rhinosinusitis With Nasal Polyps: A Prespecified Subgroup Analysis of the Phase 3 WAYPOINT Trial

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) in Chinese patients often exhibits a mixed Type 1/2/3 inflammatory phenotype (63%), potentially impacting the efficacy of biologics targeting Type 2 inflammation. This prespecified subgroup analysis of WAYPOINT (NCT04851964) evaluated the efficacy and safety of tezepelumab in Chinese
Li Hu, Houyong Li, Xicai Sun, Quan Liu, Yu Xu, Jiangang Fan, Andrew Foster, Claudia Chen, Yun Chon, Dehui Wang   +9 more
wiley   +1 more source

NASAL POLYPS

The Professional Medical Journal, 2018
Background: Nasal polyposis is a provocative situation of indefinite etiology thatinvolve nasal as well as sinus mucous membrane. Quality of life of a person can damage by nasalimpediment due to these nasal polyps. Further, it can cause of persistent postnasal drainage,hyposmia, sinusitis, taste sense change even bony demolition.
Farhan Salam, Damish Arslan, Muhammad Salman Haider Qureshi, Ejaz Ahmad   +3 more
  +6 more sources

An Unusual Presentation of Nasal Polyp: A Case Report on Ethmoid Polyposis [PDF]

, 2023
Ethmoid polyposis are the nasal polyps which are developed from ethmoidal sinuses located between the nose and eyes. Usually it is allergic in nature and can be multiple, grape like masses. The estimated ethmoid polyposis prevalence in India is 4%.
Nayanthara, Ramesh, Dhanya, Dharman, Sreelekshmy, B S, Shaiju, S Dharan, Ranjana, S R   +4 more
core   +1 more source

Inflammatory Signatures Beyond Th1/Th2 Endotypes Provide Insights Into Postoperative Recurrence in Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) represents a spectrum of inflammatory endotypes, driven by distinct T helper (Th) immune responses. The high rate of recurrent disease despite appropriate medical and surgical interventions highlights the need for improved characterization beyond the traditional type 2 and non‐type 2 phenotypes to better
Liyona Kampel, Narin N. Carmel, Shaun Edalati, Hen Chaushu, Forsan Jahshan, Yaniv Hadi, Timur Pestrikov, Leonor Leider Trejo, Nidal Muhanna, Avraham Abergel   +9 more
wiley   +1 more source

Association Between the Expression of Cytochrome P450 and Glutathione S-transferase Enzyme and Antrochoanal Polyp Pathogenesis

International Archives of Otorhinolaryngology
Introduction Antrochoanal polyp, which is a kind of smooth-surfaced single nasal polyp, is commonly present in cases of nasal obstruction. The pathogenesis of polyp formation is still unclear, but allergy is supposed to be a cause.
Mehmet Gökhan Demir, Sedat Aydın, Serpil Oguztuzun, Kayhan Basak   +3 more
doaj   +1 more source

Expression Levels of Glutathione S-Transferase and Cytochrome P450 Isoenzymes in Nasal Polyp Tissue

, 2022
Nasal polyps are benign sinonasal masses composed of eosinophils and extracellular edema. Pathogenesis of the polyp formation is unclear but several studies strongly suggest a correlation with infection, inflammation and allergy conditions. Our aim is to
Basak, Kayhan, Aydin, Sedat, Serpil Oğuztüzün, Demir, Mehmet Goekhan, Kayhan Başak, Murat Kılıç, Sedat Aydın, Büşra M. Bozer, Kilic, Murat, Oguztuezuen, Serpil, Bozer, Buesra M., Mehmet Gökhan Demir   +11 more
core   +1 more source