Results 71 to 80 of about 22,108 (285)

Dexamethasone Induces Apoptosis of Nasal Polyp-Derived Tissue Cultures Through JNK and p38 MAPK Activation [PDF]

Clinical and Experimental Otorhinolaryngology, 2014
ObjectivesGlucocorticoids, such as dexamethasone (DEX), increase apoptosis in a variety of white cells in nasal polyps and apoptosis is an important factor in the resolution of inflammation.
Tae-Hoon Lee, Jung Gwon Nam, Ho Min Lee, Bo-Young Kim, Myung-Koo Kang, Woo Yong Bae, Dae Young Hur, Seong Kook Park   +7 more
doaj   +1 more source

Flying through congested airspaces: imaging of chronic rhinosinusitis [PDF]

, 2010
The complex regional anatomy of the nose and paranasal sinuses makes the interpretation of imaging studies of these structures intimidating to many radiologists.
Davide Farina, Marco Ravanelli, Andrea Borghesi, Roberto Maroldi   +3 more
core   +1 more source

Temperature‐Controlled Radiofrequency for Severe Nasal Airway Obstruction: A Non‐Inferiority Comparison With Surgical Intervention

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Introduction Temperature‐controlled radiofrequency (TCRF), septoplasty (ST) with turbinate reduction, and functional rhinoplasty (FR) are treatment options for nasal airway obstruction (NAO) and nasal valve dysfunction (NVD), but no direct comparison of these procedures has been performed. Methods This prospective, open‐label, non‐inferiority (
Greg Davis, Zeeshan Aziz, Jose Barrera, William Blythe, Chris Davis, Steven Davis, Thomas Higgins, Charles Lano, Gregory Levitin, Frederick Lopatin, Samuel Oyer, Stacey Silvers, Ariel Waitzman, Randall Ow   +13 more
wiley   +1 more source

The Role of Platelet-Derived Growth Factor in the Pathogenesis of Sinonasal Polyps: Immunohistochemical Assessment in Epithelial, Subepithelial and Deep Layers of the Mucosa [PDF]

Clinical and Experimental Otorhinolaryngology, 2013
ObjectivesThe aim of this study is to investigate the role of platelet-derived growth factor (PDGF) in the pathogenesis of sinonasal polyps.MethodsStudy group (groups 1-3) consisted of nasal polyp samples of patients with sinonasal polyps and the control
Nuray Bayar Muluk, Osman Kürşat Arıkan, Pınar Atasoy, Rahmi Kılıç, Eda Tuna Yalçinozan   +4 more
doaj   +1 more source

Extent of Sinus Surgery Is Associated With Disease Control in Biologic Treated Type 2 Dominant CRS

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background A greater benefit of biologics is observed after surgery in Type 2 chronic rhinosinusitis with nasal polyps (CRSwNP). However, the extent of surgery remains undefined in many studies. This study evaluated the extent of surgery on disease control in patients receiving biologics for refractory Type 2 dominant CRSwNP.
Nicholas J. Campion, Peta‐Lee Sacks, Lu Hui Png, Ruoxin Hua, Rhea Darbari Kaul, Raquel Alvarado, Christine Choy, Raymond Sacks, Peter Earls, Raewyn G. Campbell, Larry Kalish, Richard J. Harvey   +11 more
wiley   +1 more source

Concordant systemic and local eosinophilia relates to poorer disease control in patients with nasal polyps

World Allergy Organization Journal, 2019
Background: Eosinophilic inflammation is a major phenotype associated with poorly controlled disease in nasal polyp patients. The difference between systemic and local eosinophilia in relation to disease control is poorly understood.
Kanghua Wang, Jie Deng, Meng Yang, Yang Chen, Fenghong Chen, Wen-Xiang Gao, Yinyan Lai, Jianbo Shi, Yueqi Sun   +8 more
doaj   +1 more source

Leptin May Promote Eosinophilic CRSwNP Progression by Enhancing Eosinophil Chemotaxis and Angiogenesis Under a Type 2 Inflammatory Milieu

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda, Yohei Sato, Yoshimasa Imoto, Mayumi Tamari, Shigeharu Fujieda   +4 more
wiley   +1 more source

Staphylococcal enterotoxin B influences the DNA methylation pattern in nasal polyp tissue : a preliminary study [PDF]

, 2013
Staphylococcal enterotoxins may influence the pro-inflammatory pattern of chronic sinus diseases via epigenetic events. This work intended to investigate the potential of staphylococcal enterotoxin B (SEB) to induce changes in the DNA methylation pattern.
Bachert, Claus, De Meyer, Tim, Denil, Simon, Perez Novo, Claudina, Trooskens, Geert, Van Cauwenberge, Paul, Van Criekinge, Wim, Zhang, Luo, Zhang, Yuan   +8 more
core   +2 more sources

Disease Remission: A Scoping Review With Thematic Analysis of the Scientific Literature With Implications for Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Remission, a term used to describe a goal of treatment for some chronic diseases, has recently been proposed for chronic rhinosinusitis (CRS). However, it is unclear what remission means for CRS and why it should serve as a goal in the present‐day treatment of CRS.
Nikhil Parail, Lynn Warner, Stacey T. Gray, Claire Hopkins, Peter H. Hwang, Sarah K. Wise, Katie M. Phillips, Ahmad R. Sedaghat   +7 more
wiley   +1 more source

Olfactory Neuroblastoma: Diagnostic Difficulty [PDF]

, 2011
Olfactory neuroblastoma is an uncommon malignant tumor of sinonasal tract arising from the olfactory neuro epithelium. The olfactory neuroblastomas presenting with divergent histomorphologies like, epithelial appearance of cells, lacking a neuro ...
Biswas, Siddhartha, MN, Vidya, S, Vijay Shankar, Shivakumar, Swarna   +3 more
core   +1 more source