Results 81 to 90 of about 16,060 (234)
Sex Hormones and the Risk of Nasal Polyps: A Two‐Sample Mendelian Randomization Study
ABSTRACT Objective The pathophysiological roles of sex hormones in airway inflammation have drawn much attention recently. We aimed to explore the causal effect of sex hormones on chronic rhinosinusitis (CRS) and nasal polyps (NP) via a Mendelian randomization (MR) study.
Ying Zhu +7 more
wiley +1 more source
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) impacts patients' concentration, ability to work, and overall quality of life. Current treatment options include topical and oral medications, and surgery. Recent evidence supports the efficacy of biologics in improving symptoms and quality of life.
Baharudin Abdullah +19 more
wiley +1 more source
Karyometric analysis of nasal polyps.
Amaç: Bu çalışmada nazal polip epitel hücrelerinin çekirdek yapıları incelendi. Hastalar ve Yöntemler: Nazal polipozis nedeniyle ameliyat edilen 35 hastanın kesitleri ve 18 normal mukoza kesiti çalışıldı. Kesitler hematoksilen-eozin ile boyandı. Doku bölümleri CCD kamera ve Mac OS 9 Karyotype Program of Human Cytogenetics Nomenclature System yardımı ...
Yildirim A. +5 more
openaire +7 more sources
ABSTRACT Purpose The rising prevalence of obesity introduces challenges in surgical contexts, including endoscopic sinus surgery (ESS) for chronic rhinosinusitis with nasal polyps (CRSwNP). However, the impact of obesity on ESS outcomes remains underexplored. This study aims to evaluate the association between obesity and surgical complexity, operative
Hen Chaushu +6 more
wiley +1 more source
The clinicopathological features of sinonasal angiomatous polyps
Yuan-Yun Tam,1,* Chia-Chen Wu,2,* Ta-Jen Lee,2 Yang-Yu Lin,3 Tai-Di Chen,4 Chi-Che Huang2 1Department of Otorhinolaryngology – Head and Neck Surgery, Lotung Poh-Ai Hospital, Yilan County, 2Department of Otorhinolaryngology – Head and ...
Tam YY +5 more
doaj
ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng +3 more
wiley +1 more source
Influence of allergy on clinical, immunological and histological characteristics of nasal polyposis
Influence of allergy on clinical, immunological and histological characteristics of nasal polyposis. Objectives: Although polyps seem to be a manifestation of the chronic inflammation of nasal/paranasal sinuses mucosa in both allergic and non-allergic ...
A. Perić +2 more
doaj +2 more sources
Decreased Production of Tissue Plasminogen Activator in Endothelial Cells From Nasal Polyps
ABSTRACT Introduction Previous studies have demonstrated that chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by excessive fibrin deposition which is related to impaired production of tissue plasminogen activator(t‐PA) by epithelial cells.
Qian‐Qian Zhang +9 more
wiley +1 more source
ABSTRACT Objective Chronic rhinosinusitis with nasal polyps (CRSwNP) is a persistent inflammatory condition often associated with other type‐2 diseases. Dupilumab, a monoclonal antibody targeting IL‐4Rα, has revolutionized the treatment of severe CRSwNP.
Pietro Orlando +17 more
wiley +1 more source
Inflammatory Shift in Chronic Rhinosinusitis Amidst Guangzhou's Urbanization (2000–2018)
ABSTRACT Background Chronic rhinosinusitis (CRS) exhibits temporal and geographic diversity in pathological endotypes with progressive eosinophilic infiltration, while the underlying causes remain unclear. Current pathological endotypes determination relies on mean cell count per high‐power field, requiring accuracy optimization.
Ning Kang +16 more
wiley +1 more source

