Olfactory Outcomes After Endoscopic Sinus Surgery for Chronic Rhinosinusitis With Nasal Polyposis
ABSTRACT Objective To evaluate subjective and objective olfactory outcomes in patients undergoing endoscopic sinus surgery (ESS) for chronic rhinosinusitis with nasal polyps (CRSwNP). Methods Prospective, single‐center study including adult patients undergoing ESS for CRSwNP from July 2022 to May 2024.
Elysia Grose +4 more
wiley +1 more source
Rare case of poorly differentiated squamous cell cancer of HPV etiology in a nasal polyp presenting as chronic sinusitis. [PDF]
Bhat SP, Wyll A, Kwon H.
europepmc +1 more source
Psychometric Validation of the Overall Symptom Severity Score for Chronic Rhinosinusitis
Abstract Objective Overall symptom severity (OSS) is a global metric of chronic rhinosinusitis (CRS) symptom severity. We sought to establish psychometric validity for the OSS, which has not been previously demonstrated in the literature. Study Design Prospective, observational. Setting Academic medical center. Methods Adult patients with CRS (N = 647)
Christine W. Lee +5 more
wiley +1 more source
ABSTRACT While the efficacy of canakinumab, an anti‐interleukin‐1β monoclonal antibody, is well‐established, its safety profile, particularly across different age groups, remains inadequately explored. Using the FDA Adverse Event Reporting System (FAERS) database, this study evaluated postmarketing safety by analyzing adverse event (AE) reports from ...
Youyang Wang +3 more
wiley +1 more source
Nasal polyp antibody-secreting cells display proliferation signature in aspirin-exacerbated respiratory disease. [PDF]
Sohail A +13 more
europepmc +1 more source
Deep Learning for Endoscopic Classification of Adenoid Hypertrophy
ABSTRACT Objective Endoscopy is a convenient and widely used method to evaluate adenoid size, but the subjectivity of its image diagnosis can result in over‐ or underestimation. To create a new assessment strategy for adenoid hypertrophy, we developed a reliable method for automated classification using a deep learning algorithm with nasal endoscopic ...
Xuan‐Sheng Wang +9 more
wiley +1 more source
The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li +4 more
wiley +1 more source
Chinese Guidelines for the Diagnosis and Surgical Treatment of Adult Obstructive Sleep Apnea (2024)
ABSTRACT Obstructive sleep apnea (OSA) is a common chronic disorder characterized by abnormal breathing during sleeping. OSA can damage various organs throughout the body and is burdensome, both socially and economically. Moreover, as OSA has been increasingly studied in recent years, new evidence‐based guidelines for its diagnosis and surgical ...
Working Group of Guideline for the Diagnosis and Surgical Treatment of Adult OSA +7 more
wiley +1 more source
Allergic Sensitization to Inhalant Allergens in the Upper Respiratory Tract—the B Cell Side
ABSTRACT Allergic diseases are on the rise worldwide, driven by respiratory epithelial barrier dysfunction that promotes sensitization to inhalant allergens such as pollen, dust mites, pet dander, and fungal spores. These antigens trigger IgE‐mediated immune responses that lead to diseases such as allergic rhinitis (AR) and asthma.
Ola Grimsholm +9 more
wiley +1 more source
Optimizing cryopreservation of nasal polyp tissue for cellular functional studies and single-cell RNA sequencing. [PDF]
Sohail A +11 more
europepmc +1 more source

