Results 191 to 200 of about 189,322 (291)

Clinical effectiveness of dupilumab in CRSwNP: unaffected by baseline nasal polyp size in real-world settings. [PDF]

open access: yesEur Arch Otorhinolaryngol
Habenbacher M   +8 more
europepmc   +1 more source

Comparing Demographic and Clinical Features of Obstructive Sleep Apnea Patients With and Without Sleepiness: A Cross‐Sectional Study

open access: yesBrain and Behavior, Volume 16, Issue 10, October 2026.
ABSTRACT Background Excessive daytime sleepiness (EDS) is a common but variable symptom in obstructive sleep apnea (OSA), with unclear associations with disease severity and clinical features. This study aimed to compare demographic and clinical characteristics of OSA patients with and without EDS in an Iranian population.
Fatemeh kashaninasab   +4 more
wiley   +1 more source

Is It Safe to Reduce Inhaled Corticosteroid Dose in Severe Asthma Patients Receiving Biologic Therapy?

open access: yesClinical and Translational Allergy, Volume 16, Issue 10, October 2026.
ABSTRACT Background Biologic therapies can control severe asthma and may modify its natural history beyond symptom control. However, step‐down is not standardized, and its safety has not been clearly established. Methods This single‐center retrospective cohort study reviewed adults with severe asthma on biologics (January 2019–May 2024).
Nagihan Orhan Özer   +4 more
wiley   +1 more source

Bioassays in Allergy: Technical Characteristics, Limitations, and Pathways to Clinical Implementation—An EAACI Position Paper

open access: yesClinical and Translational Allergy, Volume 16, Issue 10, October 2026.
ABSTRACT Bioassays offer functional readouts of immune responses through specific biomarkers, providing mechanistic insight beyond conventional serology. By capturing cellular activation, tissue‐level changes, and molecular signaling, they hold promise for refining allergy diagnosis, risk stratification, and treatment monitoring, contributing to ...
Cagatay Karaaslan   +13 more
wiley   +1 more source

Efficacy of Biologics in Aspirin Exacerbated Respiratory Disease

open access: yesClinical and Translational Allergy, Volume 16, Issue 10, October 2026.
ABSTRACT Background Aspirin‐exacerbated respiratory disease (AERD), also termed nonsteroidal anti‐inflammatory drug exacerbated respiratory disease (NERD), is characterized by asthma, chronic rhinosinusitis with nasal polyposis, and hypersensitivity to cyclooxygenase‐1 inhibitors, frequently resulting in severe, treatment‐refractory airway disease ...
Jennifer K. Priessnitz   +4 more
wiley   +1 more source

CHI3L1 on fibrinolytic system imbalance in chronic rhinosinusitis with nasal polyp. [PDF]

open access: yesFront Immunol
Yang HW   +6 more
europepmc   +1 more source

Single‐cell multi‐omics characterises transcriptional and chromatin accessibility heterogeneity of immune cells in allergic rhinitis

open access: yesClinical and Translational Medicine, Volume 16, Issue 10, October 2026.
Key Points 1. SAR and PAR showed distinct immune landscapes. 2. Macro_CCL3 showed phenotype‐specific inflammatory and antigen‐presentation features. 3. CD8_Trm displayed subtype‐associated chromatin accessibility linked to cytotoxicity‐related signatures. 4.
Yisha Wu   +7 more
wiley   +1 more source

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