Results 201 to 210 of about 22,108 (285)

Actinomycosis masquerading as a nasal polyp - a rare entity and diagnostic challenge. [PDF]

GMS Hyg Infect Control
Sakthimohan R, Rajalingam A, Johnson T, Rajan KV.   +3 more
europepmc   +1 more source

The Association Between Allergic Rhinitis, Eosinophilic Inflammation, and Postoperative Recurrence in Nasal Polyps

Otolaryngology–Head and Neck Surgery, Volume 174, Issue 5, Page 1188-1196, May 2026.
Abstract Objective Although allergic rhinitis (AR) commonly co‐occurs with chronic rhinosinusitis with nasal polyps (CRSwNP), its impact on tissue endotypes and prognosis remains unclear. This study examines the impact of AR on CRSwNP, focusing on its links to tissue eosinophilic inflammation and postoperative recurrence risk.
Wei Zhong, Shaobing Xie, Haijun He, Hua Zhang, Weihong Jiang, Can Liao, Zhihai Xie   +6 more
wiley   +1 more source

Biologic Therapies across Nasal Polyp Subtypes. [PDF]

J Pers Med
Bolk KG, Wise SK.
europepmc   +1 more source

Epigenetic Dysregulation of the NKX2‐1/SPDEF Axis Drives Persistent Goblet Cell Differentiation and Epithelial Barrier Dysfunction in Chronic Obstructive Pulmonary Disease

Respirology, Volume 31, Issue 5, Page 484-497, May 2026.
This study investigated airway epithelial barrier dysfunction persistence in ex‐smokers with COPD and underlying mechanisms using single‐cell RNA and ATAC sequencing. Epigenetic NKX2‐1/SPDEF dysregulation maintains goblet cell hyperplasia and barrier dysfunction despite long‐term smoking cessation.
Ayaka Shiota, Keiko Kan‐o, Yumiko Ishii, Tomoaki Koga, Takeshi Sawada, Kei‐ichiro Yasunaga, Shingo Usuki, Tatsuya Katsuno, Shigesato Inoue, Tomohiro Ogawa, Akihiro Jo, Satoru Fukuyama, Mitsuyoshi Nakao, Hiroaki Ogata, Mizuho A. Kido, Sachiko Tsukita, Koichiro Matsumoto, Isamu Okamoto   +17 more
wiley   +1 more source

Correlation Between Smell Recovery and Nasal Polyp Score in Patients Treated with Dupilumab: A Real-Life Retrospective, Observational, Monocentric Study. [PDF]

J Pers Med
Stilo G, Messina G, Lo Faro C, Ruta S, Frangipane S, Mariut D, Giunta G, Distefano ME, Zappalà AG, Maniaci A, Bianchi A, La Mantia I.   +11 more
europepmc   +1 more source

Nasal dermoid sinus cyst diagnosed on CT in an adult Hungarian Vizsla

Veterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract Nasal dermoid sinus cysts are rare congenital anomalies in dogs, resulting from abnormal embryological development that leads to the inclusion of ectodermal and mesodermal elements within a sinus or subcutaneous tissue, along the dorsal midline.
Athena Kam, Kerry Peak, Kathryn Fleming, Andrew Phillips   +3 more
wiley   +1 more source

Inflammatory Nasal Polyp With Benign Lymphangioendothelioma/Acquired Progressive Lymphangioma in a Young Man. [PDF]

Cureus
Yorita K, Miyazaki K, Hisaoka M, Nakatani K.   +3 more
europepmc   +1 more source

Acetylcholine From Solitary Chemosensory Cell, Not Neuron, Regulates Basal Cell Fate Driving Eosinophilic Chronic Rhinosinusitis With Nasal Polyps

Allergy, Volume 81, Issue 5, Page 1617-1634, May 2026.
This study identifies that Ach levels are elevated in eCRSwNP and primarily released from SCCs rather than neurons. Ach induces epithelial remodeling in eCRSwNP by binding to M1R/M3R and activating YAP signaling in basal cells, driving basal cell hyperplasia and abnormal differentiation. Blocking M1R/M3R with TB inhibits eCRSwNP progression.
Bowen Zheng, Tao Lu, Ji Wang, Yalan Zhang, Panhui Xiong, Jieyu Zeng, Shuman Li, Yu Jiang, Yijun Liu, Longlan Shu, Yuan Chen, Yin Zhou, Yue Gu, Dayu Guan, Chenxi Li, Lei Zhao, Shujin Wang, Jie Liu, Xia Ke, Yang Shen, Yucheng Yang   +20 more
wiley   +1 more source

CHI3L1 on fibrinolytic system imbalance in chronic rhinosinusitis with nasal polyp. [PDF]

Front Immunol
Yang HW, Park JH, Shin JM, Son HG, Kim TH, Lee SH, Park IH.   +6 more
europepmc   +1 more source

Club Cells in Nasal Epithelial Repair: Insights From an IL‐13‐Induced Inflammatory Model

Allergy, Volume 81, Issue 5, Page 1459-1471, May 2026.
Four inflammatory endotypes of CRSwNP, defined by eosinophil and neutrophil infiltration, show distinct patterns of basal, club, ciliated, and goblet cell expression in nasal epithelium. Using an ALI‐HNECs model, we demonstrate that IL‐13 impairs mucociliary function by promoting club‐to‐goblet cell differentiation while inhibiting club‐to‐ciliated ...
Zhi‐Qun Huang, Jing Liu, Jing Ye, Li‐Ying Sun, Hsiao Hui Ong, Yang Peng, Bing‐Qi Lin, Jun‐Hao Tu, Ke‐Shuang Wang, Yi‐Shan Xiong, Qing Luo, Mark Thong, Yu Xu, De‐Yun Wang   +13 more
wiley   +1 more source