Results 101 to 110 of about 517,223 (251)

Kartagener’s Syndrome Presenting As Bilateral Recurrent Nasal Polyposis In A Young Boy

Journal of Bahria University Medical and Dental College, 2018
Kartagener's syndrome is a very rare congenital disease consists of a classic triad, sinusitis, situs inversus and bronchiectasis. Approximately one half of patients with primary ciliary dyskinesia have situs inversus and Kartagener syndrome.
Zeba Ahmed, Warda Waseem, Uroosa Saman
doaj   +1 more source

Systematic literature review of humanistic and economic burdens of chronic rhinosinusitis with nasal polyposis

Current Medical Research and Opinion, 2020
Objectives We conducted a systematic literature review (SLR) of randomized controlled trials and real-world evidence (RWE) studies to determine the humanistic (e.g. health-related/disease-specific quality of life [QOL]) and economic (e.g.
Stephanie Chen, Anna Zhou, B. Emmanuel, D. Garcia, E. Rosta   +4 more
semanticscholar   +1 more source

The Origins of Allergy: An Outside‐In, Bioenergetic Hypothesis

Allergy, EarlyView.
ABSTRACT Allergic disease has risen too rapidly for inherited susceptibility to explain it, and the risk variants so far reported lie in the epithelial barrier and in type‐2 immunity. We propose a five‐layer model in which epithelial barrier and bioenergetic dysfunction may precede and promote type‐2 immune deviation rather than arise solely as its ...
Peter K. Smith, Nicholas P. West, Stanley Du Preez, Hugh A. Sampson, Peter W. Hellings, David Price, Liam O'Mahony, Carina Venter, Cezmi A. Akdis, Gil Yosipovitch   +9 more
wiley   +1 more source

Role of Biologics in Chronic Rhinosinusitis With Nasal Polyposis: State of the Art Review

Otolaryngology Head & Neck Surgery, 2020
Objective To review the current literature regarding the role of biologics in the treatment of chronic rhinosinusitis with nasal polyposis (CRSwNP). Data Sources PubMed/MEDLINE, EMBASE, Cochrane Review, ClinicalTrials.gov Review Methods We conducted a ...
Christine M. Kim, Joseph K. Han, Tara J. Wu, C. Bachert, W. Fokkens, P. Hellings, C. Hopkins, Stella E. Lee, J. Mullol, J. Lee   +9 more
semanticscholar   +1 more source

Growth Assessment in Children Under 12 Years With Moderate‐to‐Severe Atopic Dermatitis Included in the PEDISTAD Observational Registry

Pediatric Dermatology, EarlyView.
ABSTRACT Background/Objective The multifactorial disease burden of moderate‐to‐severe atopic dermatitis (AD) may affect children's growth. We report height, weight, and body mass index (BMI) of children under 12 years old with moderate‐to‐severe AD in comparison to the general population.
Amy S. Paller, Alan D. Irvine, Eulalia Baselga, Marlies de Graaf, Elaine C. Siegfried, Michael J. Cork, Michele Ramien, Lawrence F. Eichenfield, Bryan Adams, Rajan Gupta, Marius Ardeleanu, Annie Zhang   +11 more
wiley   +1 more source

No Effect of Preoperative Mepolizumab on Early Postoperative Healing After ESS for Severe CRSwNP

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 6, December 2026.
ABSTRACT Objective To evaluate postoperative endoscopic mucosal healing 2 weeks after ESS in patients with severe CRSwNP treated with surgery alone versus surgery combined with biologics initiated 2 weeks preoperatively. Methods In this exploratory post hoc analysis, patients with severe CRSwNP were divided into two cohorts: ESS alone and ESS with ...
A. S. Homøe, M. Høxbro, J. Tidemandsen, V. Backer, E. Kiaer, S. Scott, N. Rubek, K. Aanæs   +7 more
wiley   +1 more source

Influence of allergy on clinical, immunological and histological characteristics of nasal polyposis

B-ENT, 2012
Influence of allergy on clinical, immunological and histological characteristics of nasal polyposis. Objectives: Although polyps seem to be a manifestation of the chronic inflammation of nasal/paranasal sinuses mucosa in both allergic and non-allergic ...
A. Perić, D. Vojvodić, B. Vukomanović-Đurđević   +2 more
doaj   +2 more sources

Is routine histopathological analysis of nasal polyposis specimens necessary? [PDF]

, 2011
WOS: 000291170400012PubMed: 21331779Our objective is to evaluate the incidence of unexpected pathologies in routine nasal polyposis specimens and necessity for histopathological evaluation of nasal polyps. A retrospective chart review of all patients who
Koç, Sema, Huseyin Yaman, Belada, Abdullah, Yılmaz, Süleyman, Suleyman Yilmaz, Alkan, Nihal, Sema Koc, Abdullah Belada, Nihal Alkan, Yaman, Hüseyin   +9 more
core   +1 more source

Eosinophilia and Hypereosinophilia: A Practical Approach to Navigating a Broad Differential Diagnosis

European Journal of Haematology, Volume 117, Issue 6, Page 1485-1499, December 2026.
ABSTRACT Eosinophilia, defined as an absolute eosinophil count (AEC) of ≥ 0.5 × 109/L, is a frequently encountered finding with a vast spectrum of potential underlying etiologies. Hypereosinophilia (HE) is defined as AEC > 1.5 × 109/L and may become life‐threatening when eosinophil‐induced organ damage occurs, defining the hypereosinophilic syndrome ...
Stijn Wigerinck, Peter Vandenberghe
wiley   +1 more source

Tezepelumab in Chinese Patients With Severe Chronic Rhinosinusitis With Nasal Polyps: A Prespecified Subgroup Analysis of the Phase 3 WAYPOINT Trial

International Forum of Allergy &Rhinology, Volume 16, Issue 11, Page 1309-1317, November 2026.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) in Chinese patients often exhibits a mixed Type 1/2/3 inflammatory phenotype (63%), potentially impacting the efficacy of biologics targeting Type 2 inflammation. This prespecified subgroup analysis of WAYPOINT (NCT04851964) evaluated the efficacy and safety of tezepelumab in Chinese
Li Hu, Houyong Li, Xicai Sun, Quan Liu, Yu Xu, Jiangang Fan, Andrew Foster, Claudia Chen, Yun Chon, Dehui Wang   +9 more
wiley   +1 more source