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Dupilumab as Add-on Therapy for Chronic Rhinosinusitis With Nasal Polyposis in Aspirin Exacerbated Respiratory Disease

American Journal of Rhinology & Allergy, 2020
Background Aspirin-exacerbated respiratory disease (AERD) affects 7% of asthmatics. Usual therapies are inadequate for asthma and/or nasal polyposis, leading to decreased quality of life.
S. Mustafa   +3 more
semanticscholar   +1 more source

Nasal polyposis and facial pain

Clinical Otolaryngology and Allied Sciences, 2001
A cohort of 973 patients with symptoms of rhinosinusitis and/or facial pain was followed up for a mean of 2 years 2 months and, within this, was a group of 220 with nasal polyps. Only 39 (18%) had pain or pressure as a symptom. Out of the 220 with nasal polyps, 190 had polyps without any purulent secretions and, of these, only 5 (2.6%) had pain ...
C, Fahy, N S, Jones
openaire   +2 more sources

Nasal Polyposis With Invasion Into the Orbit

Archives of Otolaryngology - Head and Neck Surgery, 1983
Proptosis of the left eye developed in a 51-year-old man with a long history of nasal polyposis. Displacement of the orbit was associated with a palpable mass superior and lateral to the orbit. Roentgenographic studies, including a sinus series, computed tomographic scan, and axial tomogram of the left orbit, showed a soft-tissue mass in the ...
M, Arab, M, Friedman, J, Weingarten
openaire   +2 more sources

Nasal polyposis

2018
This chapter discusses Rimmer, Fokkens, Chong, and Hopkins’s paper on surgical versus medical interventions for chronic rhinosinusitis with nasal polyps including the design of the study (outcome measures, results, conclusions, and a critique).
openaire   +2 more sources

Dupilumab improves health‐related quality of life in patients with chronic rhinosinusitis with nasal polyposis

Allergy. European Journal of Allergy and Clinical Immunology, 2019
Chronic rhinosinusitis with nasal polyposis (CRSwNP) negatively affects health‐related quality of life (HRQoL). In a previously reported randomized clinical trial (NCT01920893), addition of dupilumab to mometasone furoate in patients with CRSwNP ...
C. Bachert   +17 more
semanticscholar   +1 more source

Participation of complement in nasal polyposis

Folia Microbiologica, 1993
No changes in immunoglobulin (IgG, IgM and IgA) and complement components C3 and C4 levels could be observed in patients suffering from both recurrent and acute nasal polyposis. However, in both groups of patients a significant decrease of the alternative pathway of complement activation (up to 80%) was found.
J, Zídková   +4 more
openaire   +2 more sources

Inflammatory genes in nasal polyposis

Current Opinion in Otolaryngology & Head & Neck Surgery, 2008
This paper is a review of the most recent literature concerning the role of inflammatory genes in nasal polyposis. The data provide evidence of a pivotal role for some inflammatory mediators in the development and maintenance of nasal polyps.Nasal polyposis is a common disease of the nasal mucosa; the exact mechanisms leading its development are still ...
Claudia Regina, Figueiredo   +2 more
openaire   +2 more sources

Rhinoscleroma Mimicking Nasal Polyposis

Annals of Otology, Rhinology & Laryngology, 2001
Rhinoscleroma is increasing in incidence in the United States. It should be considered in patients who are immigrants from endemic countries and present with nasal polyposis that exhibits significant adherence to the nasal septum and relative sparing of the sinuses.
M E, Ammar, A, Rosen
openaire   +2 more sources

[Nasal polyposis].

Duodecim; laaketieteellinen aikakauskirja, 2012
Nasal polyposis is an adult type mucosal inflammation of unknown etiology. Polyps are found in 4% of the Finns and in 17% of asthma patients. The first-line treatment is corticosteroid nasal spray and, if necessary, corticosteroid nasal drops or orally administered corticosteroids.
Seija, Vento, Paula, Virkkula
openaire   +1 more source

Nasal polyposis.

The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society, 1991
Nasal polyps are the most common tumors arising in the nasal cavities. They are thought to affect between 1% and 4% of the population. Various conditions predispose to nasal polyp formation, and the mechanisms of these associations are in some instances still undefined.
J P, Kirsch, J A, White
openaire   +1 more source

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