Results 111 to 120 of about 48,438 (295)

Impact of Life‐Context Factors on Chronic Rhinosinusitis 22‐Item Sinonasal Outcomes Test: Systematic Review + Meta‐Analysis

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Chronic rhinosinusitis (CRS) affects all sociodemographic groups. While studies have explored social determinants of health (SDOH), sociodemographics, and health behaviors, their specific effects on CRS outcomes are unclear, making tailored care difficult.
Kassandra M. Jade, George A. Scangas, Victoria S. Lee, Li‐Xing Man, Edward D. McCoul, Gabriela Guevara, Anahita Nourmahnad, John M. Reynolds, Corinna G. Levine   +8 more
wiley   +1 more source

Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies–A Systematic Review

Phytotherapy Research, EarlyView.
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández, Sara Elis Bianchi, Flávia Nathiely Silveira Fachel, Elizandra Braganhol, Sheila Porto de Matos, Valquíria Linck Bassani   +5 more
wiley   +1 more source

Variations in the Severity of Rhinitis Symptoms: A Systematic Review and Meta‐Analysis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Key rhinitis symptoms include nasal obstruction, rhinorrhea, sneezing, and nasal itching. Different subtypes of rhinitis can have varying presentations, making it difficult to diagnose and categorize. The objective of this review is to characterize the baseline presentation of rhinitis and highlight differences in the presentation of
Asher T. Ripp, Pranav A. Patel, Shaun A. Nguyen, Isabella V. Schafer, Alexander N. Duffy, Zachary M. Soler, Rodney J. Schlosser   +6 more
wiley   +1 more source

A in nasal polyps and laryngeal disorders

, 2009
OBJECTIVE: To identify Helicobacter pylori and major virulance factor, cagA, in patients with laryngeal diseases and nasal ...
Mustafa Ozyurt, Erkul, Evren, ERGÜNAY, KORAY, Evren Erkul, Tuncer Haznedaroglu, Ozyurt, Mustafa, Koray Ergunay, Cekin, Engin, Haznedaroglu, Tuncer, Engin Cekin, Atila Gungor, Gungor, Atila   +11 more
core   +1 more source

Integrative Analysis of Plasma Proteome and Genome Reveals Novel Drug Targets for Chronic Rhinosinusitis and Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) and nasal polyps (NP) are chronic inflammatory conditions with unsatisfactory treatment outcomes due to frequent recurrence of refractory disease. Identifying new therapeutic targets is essential. Methods We conducted a proteome‐wide Mendelian randomization (MR) analysis by integrating genome‐wide ...
En Zhou, Shi Luo, Yu Xiao, Bin Liu, Xu‐Ping Xiao   +4 more
wiley   +1 more source

Improvement of Mixed Inflammatory Environment in Nasal Secretions of Diffuse Type 2 Chronic Rhinosinusitis With Nasal Polyps Under Dupilumab. [PDF]

Clin Transl Allergy
ABSTRACT Background In Western countries, Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) is predominantly associated with a type 2 inflammatory endotype. While nasal secretion analysis shows promise for disease endotyping, current biomarkers remain limited for accurate stratification, disease monitoring, and prediction of treatment response ...
Ryser FS, Mauthe T, Brühlmann C, Soyka MB, Steiner UC.   +4 more
europepmc   +2 more sources

Sex Hormones and the Risk of Nasal Polyps: A Two‐Sample Mendelian Randomization Study

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective The pathophysiological roles of sex hormones in airway inflammation have drawn much attention recently. We aimed to explore the causal effect of sex hormones on chronic rhinosinusitis (CRS) and nasal polyps (NP) via a Mendelian randomization (MR) study.
Ying Zhu, Jia‐Yao Zhou, Shi‐Yao Zhang, Ru Tang, Chun‐Yu Luo, Yue‐Long Gu, Zhi‐Peng Li, Wei‐Tian Zhang   +7 more
wiley   +1 more source

The use of Omalizumab in the treatment of nasal polyps

, 2015
It is often that patients with nasal polyps may suffer from asthma. Both, nasal polyps and asthma, share the same features, inflammation, eosinophilia and local IgE formation. Omalizumab, as an anti-IgE mAb, is proven to be effective in treating allergic
Yakinthou, A, Megas, I, Tsavlis, D
core   +1 more source

A Delphi Consensus on Clinical Features, Diagnosis, and Treatment of Chronic Rhinosinusitis With Nasal Polyps in the ASEAN Region

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) impacts patients' concentration, ability to work, and overall quality of life. Current treatment options include topical and oral medications, and surgery. Recent evidence supports the efficacy of biologics in improving symptoms and quality of life.
Baharudin Abdullah, Revadi Govindaraju, Salina Husain, Jin Keat Siow, Pongsakorn Tantilipikorn, Neville Wei Yang Teo, De Yun Wang, Deasi Anggraini, Tze Choong Charn, Chao‐Wu David Chin, Dichapong Kanjanawasee, Maung Maung Khaing, Jern‐Lin Leong, Luan Viet Tran, Harvinder Singh, Ing Ping Tang, Kim Thye Mark Thong, Gil M. Vicente, Yoke Yeow Yap, Soma Subramaniam   +19 more
wiley   +1 more source

Level of Interleukin IL13 in Serum and Nasal Secretions of Allergic Nasal Polypi Patients

Arcades of Medicine
Background: Allergic nasal polyposis is a chronic inflammatory condition commonly associated with type 2 immune responses and elevated cytokines, particularly interleukin-13 (IL-13).
Hesham Mizar, Maged Baher, Amr Hegab, mohamed Elsawy   +3 more
doaj   +1 more source