Results 241 to 250 of about 62,516 (342)

Effectiveness of dupilumab in chronic rhinosinusitis with nasal polyps: A retrospective study of clinical and imaging outcomes. [PDF]

open access: yesSaudi Med J
Alhejaily MA   +7 more
europepmc   +1 more source

A Case of CSNK2A1 Gene Variant Causing Okur‐Chung Syndrome and Analysis of the Clinical Phenotypic Spectrum

open access: yesMolecular Genetics &Genomic Medicine, Volume 13, Issue 12, December 2025.
In the present study, a de novo variant of the CSNK2A1 gene, designated c.149A>G (p.Tyr50Cys), was identified in a subject diagnosed with OCNDS by WES. The molecular mechanism by which this variant leads to a wide range of clinical phenotypes by disrupting the kinase domain function was elucidated through a combination of experimental investigation and
Xin Li   +6 more
wiley   +1 more source

Trends and future directions in chronic rhinosinusitis with nasal polyps: A bibliometric analysis. [PDF]

open access: yesBraz J Otorhinolaryngol
Zhong Y   +6 more
europepmc   +1 more source

Relevance of Epithelial Damage and Basement Membrane Thickness to Eosinophilic Infiltration in Nasal Polyps of Chronic Rhinosinusitis

open access: green, 2009
Tatsuya Saitoh   +9 more
openalex   +1 more source

The Ketamine Trial for Acute Suicidality (KETA): Study Protocol of a Double‐Blind Randomized Placebo‐Controlled Superiority Trial on Intranasal Racemic Ketamine Compared to the Active Placebo Intranasal Midazolam as Treatment for Acute Suicidality

open access: yesInternational Journal of Methods in Psychiatric Research, Volume 34, Issue 4, December 2025.
ABSTRACT Background Suicidality is a transdiagnostic entity in patients with and without psychiatric disorders. Ketamine is a novel treatment for treatment‐resistant depression with favorable effects on related suicidality in this population. Little is known about the effects of ketamine on suicidality as a distinct phenomenon.
Jurriaan F. M. Strous   +5 more
wiley   +1 more source

Advanced Age in Sinus Surgery: Diminished Symptom Gains but Enhanced Surgical Durability in Chronic Rhinosinusitis

open access: yesOtolaryngology–Head and Neck Surgery, Volume 173, Issue 6, Page 1348-1358, December 2025.
Abstract Objective To assess whether patients of advanced age with chronic rhinosinusitis (CRS) experience comparable symptom improvement and disease control following endoscopic sinus surgery (ESS) compared to younger patients. Data Sources Systematic searches were performed across PubMed, Embase, Web of Science, Scopus, and CENTRAL to May 2024 ...
Ahmad A. Mirza   +6 more
wiley   +1 more source

Oral corticosteroid overexposure: characterizing oral corticosteroid use in patients with chronic rhinosinusitis with nasal polypS in Canada (ACTIONS) results. [PDF]

open access: yesAllergy Asthma Clin Immunol
Chan Y   +9 more
europepmc   +1 more source

Taste and Smell Disorders in Children and Young Adults With Cystic Fibrosis and Primary Ciliary Dyskinesia—A Prospective Comparative Study

open access: yesPediatric Pulmonology, Volume 60, Issue 12, December 2025.
ABSTRACT Background In cystic fibrosis (CF), the defect of the CF transmembrane conductance regulator (CFTR) can also affect sensory nerve cell function, as recently demonstrated in animal models. The aim of this prospective cohort study was to investigate whether taste and smell disorders in CF correlate with persistent CFTR dysfunction detectable by ...
Lea Christiane Beermann   +9 more
wiley   +1 more source

Optimising care for chronic rhinosinusitis with nasal polyps and asthma in multimorbid patients: a multidisciplinary Delphi consensus. [PDF]

open access: yesActa Otorhinolaryngol Ital
De Corso E   +45 more
europepmc   +1 more source

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