Results 111 to 120 of about 15,700 (277)

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai, Jingchen Zhai, Beihong Ji, Fengyang Han, Taoyu Niu, Luxuan Wang, Junmei Wang   +6 more
wiley   +1 more source

Integrative Analysis of Plasma Proteome and Genome Reveals Novel Drug Targets for Chronic Rhinosinusitis and Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) and nasal polyps (NP) are chronic inflammatory conditions with unsatisfactory treatment outcomes due to frequent recurrence of refractory disease. Identifying new therapeutic targets is essential. Methods We conducted a proteome‐wide Mendelian randomization (MR) analysis by integrating genome‐wide ...
En Zhou, Shi Luo, Yu Xiao, Bin Liu, Xu‐Ping Xiao   +4 more
wiley   +1 more source

Development of a questionnaire to assess experience and preference of intranasal corticosteroids in patients with allergic rhinitis

Patient Related Outcome Measures, 2011
Bruce Crawford1, Richard H Stanford2, Audrey Y Wong1, Anand A Dalal2, Martha S Bayliss11Mapi Values, Boston, MA, USA; 2GlaxoSmithKline, Research Triangle Park, NC, USABackground: Allergic rhinitis affects 10%–20% of the US population.
Crawford B, Stanford R, Wong AY, Dalal A, Bayliss M   +4 more
doaj  

Análisis del manejo de la nasofaringitis aguda en Atención Primaria en zona de salud rural. Un estudio descriptivo [PDF]

, 2012
INTRODUCCIÓ: nasofaringitis aguda (NFA) malaltia infecciosa amb elevada morbiditat-demanda en Atenció Primària. OBJECTIUS: adherència dels metges a la guia semfyc, conèixer patró epidemiològic i despesa en NFA.
Palomar Peris, Gonzalo, Segura Porta, Ferran, Universitat Autònoma de Barcelona. Departament de Medicina, Universitat Autònoma de Barcelona. Facultat de Medicina   +3 more
core  

A Delphi Consensus on Clinical Features, Diagnosis, and Treatment of Chronic Rhinosinusitis With Nasal Polyps in the ASEAN Region

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) impacts patients' concentration, ability to work, and overall quality of life. Current treatment options include topical and oral medications, and surgery. Recent evidence supports the efficacy of biologics in improving symptoms and quality of life.
Baharudin Abdullah, Revadi Govindaraju, Salina Husain, Jin Keat Siow, Pongsakorn Tantilipikorn, Neville Wei Yang Teo, De Yun Wang, Deasi Anggraini, Tze Choong Charn, Chao‐Wu David Chin, Dichapong Kanjanawasee, Maung Maung Khaing, Jern‐Lin Leong, Luan Viet Tran, Harvinder Singh, Ing Ping Tang, Kim Thye Mark Thong, Gil M. Vicente, Yoke Yeow Yap, Soma Subramaniam   +19 more
wiley   +1 more source

Healthcare professionals’ and patients’ views and experiences of surgical and medical treatment for nasal obstruction: a qualitative interview study for a Nasal Airway Obstruction Study (NAIROS)

BMJ Open
Objectives To understand healthcare professionals’ and patients’ views and experiences of septoplasty and medical management (ie, nasal steroid and saline sprays) for nasal obstruction.Design Nested qualitative study as part of the Nasal Airway ...
Leila Rooshenas, David Hamilton, Nikki Rousseau, Emma Clark, Janet A Wilson, Caroline Wilson, Sean Carrie, Kelly E Lloyd   +7 more
doaj   +1 more source

A Clinical Study to Assess the Efficacy and Safety of MP-AzeFlu Nasal Spray in Comparison to Commercially Available Azelastine Hydrochloride and Fluticasone Propionate Nasal Sprays in Chinese Volunteers with Allergic Rhinitis. [PDF]

Pulm Ther, 2023
Zhou B, Cheng L, Pan J, Wang H, Jin Y, Zhao C, Lin P, Tan G, Fang H, Zhang H, Zhou H, Dong Y, Kuhl HC, Ramalingam RK, Nguyen DT.   +14 more
europepmc   +1 more source

Obesity and Its Impact on Endoscopic Sinus Surgery Outcomes in Patients With Chronic Rhinosinusitis With Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Purpose The rising prevalence of obesity introduces challenges in surgical contexts, including endoscopic sinus surgery (ESS) for chronic rhinosinusitis with nasal polyps (CRSwNP). However, the impact of obesity on ESS outcomes remains underexplored. This study aims to evaluate the association between obesity and surgical complexity, operative
Hen Chaushu, Narin Nard Carmel Neiderman, Yuval Presman, Alexandra Dorman, Roni Vass, Nidal Muhanna, Avraham Abergel   +6 more
wiley   +1 more source

TOPIC DECONGESTANTS IN COMPLEX THERAPY OF UPPER AIRWAYS DISEASES

Педиатрическая фармакология, 2006
In the complex treatment of the inflammatory diseases of ENT-organs (rhinitis, sinusitis, tubootitis and otitis media) vasoconstrictors (topic decongestants) are locally applied. Besides, they're used in diagnosing of nasal cavity diseases.
G.D. Tarasova
doaj   +2 more sources