Results 221 to 230 of about 846,625 (333)

Nanoformulated Diacerein Alleviates Hyperlipidemia via Gut Microbiota Modulation In Vivo

Nano Select, EarlyView.
A nanoformulation of diacerein (Nano‐DIA) was fabricated with carboxymethyl cellulose, achieving enhanced solubility and rapid dissolution for alternative anti‐hyperlipidemia therapeutics. Mechanistic studies revealed its in vivo lipid‐lowering efficacy is through metabolite‐mediated and microbiota‐dependent manner, highlighting its dual action on host
Zheng Peng, Yi Yu, Mingyi Chen, Weibin Wu, Chunyan Zhu, Caisheng Wu, Weihua Li, Zehua Liu, Qiang Xie   +8 more
wiley   +1 more source

Big data dimensionality reduction-based supervised machine learning algorithms for NASH diagnosis. [PDF]

BMC Bioinformatics
Tutsoy O, Ozturk HA, Sumbul HE.
europepmc   +1 more source

Personalized Differential Privacy for Ridge Regression Under Output Perturbation

Naval Research Logistics (NRL), EarlyView.
ABSTRACT The increased application of machine learning (ML) in sensitive domains requires protecting the training data through privacy frameworks, such as differential privacy (DP). Traditional DP enforces a uniform privacy level ε$$ \varepsilon $$, which bounds the maximum privacy loss that each data point in the dataset is allowed to incur.
Krishna Acharya, Franziska Boenisch, Rakshit Naidu, Juba Ziani   +3 more
wiley   +1 more source

The Construction and Performance Evaluation of a Risk Prediction Model for Nonalcoholic Steatohepatitis Based on Serological Markers. [PDF]

Gastroenterol Res Pract
Huang D, Zhang W, Fang Y, Liu T, Zhou D.
europepmc   +1 more source

From NASH to diabetes and from diabetes to NASH: Mechanisms and treatment options

JHEP Reports, 2019
A. Gastaldelli, K. Cusi
semanticscholar   +1 more source

Recurrent Jejunal Diverticulitis: A Rare Cause of Acute Abdomen. [PDF]

Gastro Hep Adv
Al-Obaidi O, Cheng S, Nash E.
europepmc   +1 more source

Disease Burden of Liver Cancer and Its Underlying Etiologies Globally and in China From 1990 to 2021: Results From the Global Burden of Disease Study 2021

Portal Hypertension &Cirrhosis, EarlyView.
Liver cancer remains a leading global health threat, imposing a substantial and growing burden of disease and disability. This study explores the epidemiologic landscape of liver cancer worldwide and within China over recent decade using Global Burden of Disease database 2021 study.
Jiaqi Ruan, Hangkai Huang, Chengfu Xu
wiley   +1 more source

Exploring the potential mechanisms of OSBPL3 in metabolic dysfunction-associated steatotic liver disease by integrating bulk and single-cell RNA sequencing data. [PDF]

Medicine (Baltimore)
Wang Q, Zhu C, Xiao Y, Wang X, Song W, Li S, Jiang F, Wei L, Hua F.   +8 more
europepmc   +1 more source

Hepatic fibrosis in patients diagnosed with rheumatoid arthritis and psoriatic arthritis receiving methotrexate: A cross‐sectional analysis using transient elastography

Rheumatology &Autoimmunity, EarlyView.
Hepatic fibrosis and metabolic syndrome are more prevalent in PsA patients treated with methotrexate, compared to RA patients. Metabolic syndrome is associated with the risk of hepatic fibrosis in patients diagnosed with PsA and RA even after adjustment forcumulative methotrexate exposure.
Ratchaya Lertnawapan, Soonthorn Chonprasertsuk, Sith Siramolpiwat, Kanon Jatuworapruk   +3 more
wiley   +1 more source