Results 101 to 110 of about 1,451,429 (415)

Camrelizumab and apatinib plus induction chemotherapy and concurrent chemoradiotherapy in stage N3 nasopharyngeal carcinoma: a phase 2 clinical trial

Nature Communications
The antiangiogenic agent apatinib has been shown to clinically improve responses to immune checkpoint inhibitors in several cancer types. Patients with N3 nasopharyngeal carcinoma have a high risk of distant metastasis, however, if the addition of ...
Hu Liang, Yao-Fei Jiang, Guo-Ying Liu, Lin Wang, Jian-Wei Wang, Nian Lu, Wei-Xiong Xia, Liang-Ru Ke, Yan-Fang Ye, Jin-Lin Duan, Wei-Xin Bei, Shu-Hui Dong, Wang-Zhong Li, Li-Ting Liu, Chong Zhao, Changqing Xie, Yan-Qun Xiang   +16 more
doaj   +1 more source

Radiation-induced root surface caries restored with glass-ionomer cement placed in conventional and ART cavity preparations: Results at two years [PDF]

, 2005
The document attached has been archived with permission from the Australian Dental Association (8th Jan 2008). An external link to the publisher’s copy is included.Background: There are no published studies comparing the clinical performances of more ...
American Dental Association., Brown LR, Gao W., Haveman CW, Hu J Y, Huber MA, McComb D., Sindhu R., Vissink A., Vissink A., Weerheijm KL, Wood RE, Yip HK, Yu C.   +13 more
core   +2 more sources

The INAVA mRNA in Extracellular Vesicles Activates Normal Ovarian Fibroblasts by Phosphorylation–Ubiquitylation Crosstalk of HMGA2

Advanced Science, EarlyView.
Ovarian cancer‐derived extracellular vesicles (EVs) transfer INAVA mRNA to normal ovarian fibroblasts (NOFs). Translated INAVA protein inhibits HMGA2 phosphorylation‐dependent ubiquitylation and proteasomal degradation, promoting NOF activation.
Lingkai Gu, Zhangjin Shen, Shizhen Shen, Conghui Wang, Yuwan Liu, Xinyi Wei, Mengxia Zheng, Jiaxin Gu, Xiaojing Chen, Yi Sun, Junfen Xu, Yan Lu, Weiguo Lu   +12 more
wiley   +1 more source

Structure and Antigenicity of Kaposi's Sarcoma‐Associated Herpesvirus Glycoprotein B

Advanced Science, EarlyView.
Kaposi's sarcoma‐associated herpesvirus (KSHV) causes severe cancers without effective treatments. This study presents an atomic model of KSHV's critical infection protein, gB, revealing a unique structure shared with related herpesviruses like Epstein‐Barr virus (EBV). The structural similarity highlights vulnerable targets for antibodies, guiding the
Xin‐Yan Fang, Cong Sun, Chu Xie, Bing‐Zhen Cheng, Zheng‐Zhou Lu, Ge‐Xin Zhao, Sen‐Fang Sui, Mu‐Sheng Zeng, Zheng Liu   +8 more
wiley   +1 more source

Toripalimab plus capecitabine in the treatment of patients with residual nasopharyngeal carcinoma: a single-arm phase 2 trial

Nature Communications
Patients with residual nasopharyngeal carcinoma after receiving definitive treatment have poor prognoses. Although immune checkpoint therapies have achieved breakthroughs for treating recurrent and metastatic nasopharyngeal carcinoma, none of these ...
Xun Cao, Hao-Yang Huang, Chi-Xiong Liang, Zhuo-Chen Lin, Jia-Yu Zhou, Xi Chen, Ying-Ying Huang, Ze-Jiang Zhan, Liang-Ru Ke, Lu-Jun Han, Wei-Xiong Xia, Lin-Quan Tang, Shan-Shan Guo, Hu Liang, Xiang Guo, Xing Lv   +15 more
doaj   +1 more source

The Prognostic Role of Plasma Epstein-Barr Virus DNA Levels in the Middle of Intensity Modulated Radiation Therapy to Guide Cisplatin Dose Recommendation in Concurrent Chemoradiation Therapy in Patients With Locally Advanced Nasopharyngeal Carcinoma: A Large Cohort Study

Advances in Radiation Oncology, 2022
Purpose: Our purpose was to investigate the prognostic role of plasma Epstein-Barr virus (EBV) DNA levels in the middle of intensity modulated radiation therapy (IMRT).
Zhen-Chong Yang, MD, Chao-Chao Du, PhD, Li-Ting Liu, MD, Yu-Jing Liang, MD, Lin-Quan Tang, MD, Qiu-Yan Chen, MD, Hai-Qiang Mai, MD, PhD, Shan-Shan Guo, MD   +7 more
doaj  

Penalized Poisson model for network meta-analysis of individual patient time-to-event data [PDF]

arXiv, 2021
Network meta-analysis (NMA) allows the combination of direct and indirect evidence from a set of randomized clinical trials. Performing NMA using individual patient data (IPD) is considered as a "gold standard" approach as it provides several advantages over NMA based on aggregate data. For example, it allows to perform advanced modelling of covariates
arxiv  

Stage T4B head and neck cancer survival outcome comparisons based on treatment modality: is surgery a viable treatment option? [PDF]

, 2016
IMPORTANCE: Advanced stage head and neck cancers are often deemed unresectable due to the aggressive nature of the cancer. In evaluating survival patterns of patients with stage IVb tumors, it is valuable to determine whether patients who undergo ...
Kidwai, Neiha
core   +1 more source

Liquid biopsy tracking during sequential chemo-radiotherapy identifies distinct prognostic phenotypes in nasopharyngeal carcinoma

Nature Communications, 2019
Liquid biopsies have the utility for detecting minimal residual disease in several cancer types. Here, we investigate if liquid biopsy tracking on-treatment informs on tumour phenotypes by longitudinally quantifying circulating Epstein-barr virus (EBV ...
J. Lv, Yupei Chen, G. Zhou, Z. Qi, K. L. Tan, Haitao Wang, Li Lin, Fo-Ping Chen, Lulu Zhang, Xiao-Dan Huang, Rui-Qi Liu, Si-Si Xu, Yue Chen, Jun Ma, M. Chua, Ying Sun   +15 more
semanticscholar   +1 more source

Nasopharyngeal carcinoma in Uganda [PDF]

Cancer, 1972
Review of histologic material seen in Uganda over the 5-year period, 1964–1968, revealed 83 cases of nasopharyngeal carcinoma out of a total of 7,000 malignant tumors. All tumors conformed to the anaplastic type, but those with a small cell structure occurred in older men than those made up of larger cells. The histologic appearances of this tumor were
A. C. Templeton, R. Schmauz
openaire   +3 more sources