Results 111 to 120 of about 1,451,429 (415)

Radiation Exposure Induced Blood–Brain Barrier Injury via Mitochondria‐Mediated Sterile Inflammation

Advanced Science, EarlyView.
This work describes a blood–brain barrier (BBB) microphysiological system (MPS) to explore the responses of BBB to radiation exposure. Following radiation exposure, obvious BBB comprise and brain endothelial injuries are detected. Mechanism study shows radiation induced significant sterile inflammation via mitochondrial dysfunction and cGAS‐STING ...
Peng Wang, Jiayue Liu, Min Zhang, Juan Yang, Peihan Lian, Xiu Cheng, Jianhua Qin   +6 more
wiley   +1 more source

Joint modeling of longitudinal health-related quality of life during concurrent chemoradiotherapy period and long-term survival among patients with advanced nasopharyngeal carcinoma

Radiation Oncology
Background To investigate the prognosis of longitudinal health-related quality of life (HRQOL) during concurrent chemoradiotherapy (CCRT) on survival outcomes in patients with advanced nasopharyngeal carcinoma (NPC).
Ji-Bin Li, Shan-Shan Guo, Ting Liu, Zhuo-Chen Lin, Wei-Jie Gong, Lin-Quan Tang, Ling Guo, Hao-Yuan Mo, Hai-Qiang Mai, Qiu-Yan Chen   +9 more
doaj   +1 more source

The evolution of nasopharyngeal carcinoma staging.

British Journal of Radiology, 2019
The prevalence of nasopharyngeal carcinoma is characterized by an unbalanced distribution: the disease is particularly prevalent in East and Southeast Asia. In this article, we review the evolution of the International Union Against Cancer/American Joint
R. Guo, Y. Mao, L. Tang, Lei Chen, Ying Sun, Jun Ma   +5 more
semanticscholar   +1 more source

MicroRNAs in nasopharyngeal carcinoma

Chinese Journal of Cancer, 2014
MicroRNAs (miRNAs) provide insight into both the biology and clinical behavior of many human cancers, including nasopharyngeal carcinoma (NPC). The dysregulation of miRNAs in NPC results in a variety of tumor-promoting effects. Furthermore, several miRNAs are prognostic markers for NPC.
Fei-Fei Liu, Jeff Bruce
openaire   +2 more sources

Review of Nasopharyngeal Carcinoma [PDF]

Ear, Nose & Throat Journal, 2006
We review the literature on nasopharyngeal carcinoma that has been published within the past 5 years. Nasopharyngeal carcinoma is a highly morbid disease, and survival is poor. Its management remains extremely difficult, not just for otolaryngologists but for radiation oncologists and medical oncologists, as well. A clear understanding of its etiology
Anita Jeyakumar, Timothy D. Doerr, Todd M. Brickman, Alwin Jeyakumar   +3 more
openaire   +3 more sources

C1q+ Macrophage–Tumor Cell Interaction Promoted Tumorigenesis via GPR17/PI3K/AKT Pathway Induced DNA Hypermethylation in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
In the TME of NPC, C1q secreted by C1q+ TAMs interacted with GPR17 to activate PI3K/AKT signaling through strengthening GPR17 coupling PI3K and increasing calcium levels in tumor cells. The activated PI3K/AKT signaling further induces DNA hypermethylation to promote the malignancy and stemness of tumor cells.
Yunzhi Liu, Cuicui Huang, Min Luo, Wenfu Lu, Baifeng Zhang, Lu Bai, Shuyue Zheng, Yanan Tan, Shanshan Li, Huali Wang, Lanqi Gong, Xinyuan Guan   +11 more
wiley   +1 more source

Comparison of long-term quality of life and their predictors in survivors between paediatric and adult nasopharyngeal carcinoma in the intensity-modulated radiotherapy era

BMC Cancer
Background To compare the differences in long-term quality of life (QoL) between survivors of paediatric and adult patients with nasopharyngeal carcinoma (NPC) and assess the clinical factors that predict long-term QoL.
Jing Jin, Shan-Shan Guo, Li-Ting Liu, Dong-Xiang Wen, Rong-Ping Liu, Jie-Yi Lin, Si-Qi Liu, Xue-Song Sun, Yu-Jing Liang, Lin-Quan Tang, Hai-Qiang Mai, Qiu-Yan Chen   +11 more
doaj   +1 more source

CDDSA: Contrastive Domain Disentanglement and Style Augmentation for Generalizable Medical Image Segmentation [PDF]

arXiv, 2022
Generalization to previously unseen images with potential domain shifts and different styles is essential for clinically applicable medical image segmentation, and the ability to disentangle domain-specific and domain-invariant features is key for achieving Domain Generalization (DG).
arxiv  

EPIDEMIOLOGICAL STUDY ON HEAD AND NECK MALIGNANCIES - A STUDY OF 150 CASES [PDF]

, 2013
OBJECTIVE: In the present study we investigate the head and Neck Malignancy cases presenting to the ENT department of our Hospital, and analyze the same to give inputs as to the incidence of head and neck malignancies, the symptoms and stage of ...
Gopalakrishnan, SankaraNarayanan, Kumar, Praveen   +1 more
core   +1 more source

High CTLA-4 expression correlates with poor prognosis in thymoma patients [PDF]

, 2018
Thymomas, tumors that arise from epithelial cells of the thymus gland, are the most common neoplasms of the anterior mediastinum, with an incidence rate of approximately 2.5 per million/year.
Amantini, Consuelo, Berardi, Rossana, Bernardini, Giovanni, Cardinali, Claudio, Marinelli, Oliviero, Morelli, Maria Beatrice, Morgese, Francesca, Nabissi, Massimo, Paolucci, Vittorio, Rinaldi, Silvia, Santoni, Giorgio, Santoni, Matteo, Tomassoni, Daniele, Torniai, Mariangela   +13 more
core   +1 more source