Results 181 to 190 of about 61,475 (266)

Necrotic Features in Post‐Radiation Nasopharyngeal Biopsies Associated With Carotid Blowout

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 4, August 2026.
This study characterizes two distinct histological patterns of post‐radiation nasopharyngeal necrosis—coagulative stromal necrosis (Type A) and microscopic osteoradionecrosis (Type B)—that are strongly associated with carotid blowout syndrome (CBS). Identifying these specific necrotic features in routine biopsies offers critical prognostic value beyond
Shan‐Chi Yu, Chun‐Nan Chen, Mei‐Chun Lin, Tseng‐Cheng Chen, Cheng‐Ping Wang, Tsung‐Lin Yang, Pei‐Jen Lou   +6 more
wiley   +1 more source

Expression of Glycoprotein B (gB) Correlates With Poor Prognosis in Nasopharyngeal Carcinoma. [PDF]

Cancer Sci
Komura S, Kondo S, Kawasaki H, Watanabe S, Yamada S, Dochi H, Nguyen HG, Ohta I, Moriyama-Kita M, Fukuyo M, Wakae K, Kitagawa Y, Mizokami H, Liu L, Hirai N, Kobayashi E, Ueno T, Nakanishi Y, Endo K, Sugimoto H, Wakisaka N, Hanayama R, Misawa K, Kaneda A, Yoshizaki T.   +24 more
europepmc   +1 more source

The Dual Role of the Gut Microbiota in Cancer Chemoresistance

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Comparison between Microbiota and Cancer therapy. ABSTRACT Chemoresistance is one of the primary reasons that cancer chemotherapy fails to deliver successful treatment outcomes and contributes to poor overall survival rates for patients with cancer. New research has begun to shed light on the effects of the gut microbiome (GM).
Hamed Tahmasebi, Aisa Bahar, Meisam Khazaei, Mohammad Reza Arabestani   +3 more
wiley   +1 more source

PPP2R2C confers radioresistance in nasopharyngeal carcinoma by suppressing ferroptosis via RPS27L stabilization. [PDF]

Cell Death Dis
Fang J, Yang Q, Yang L, Liu H, Hu S, Shen W, Zhang Y, Shen J, Wei T, Lyu Q, Luo P, Wu X, Zhang J, Meng H.   +13 more
europepmc   +1 more source

EphA2/SHP2/SOX8 Axis: A Novel Target for Regulation of Migration and Cetuximab Treatment Sensitivity in Oral Squamous Cell Carcinoma

Molecular Carcinogenesis, Volume 65, Issue 8, Page 977-988, August 2026.
ABSTRACT The development of resistance to anticancer therapies in cancer cell is a major challenge in the treatment of oral squamous cell carcinoma (OSCC), a common malignant tumor. Erythropoietin‐producing hepatocellular A2 (EphA2) affects several cancers, and this study examined its role in enhancing OSCC.
Dayong Yan, Lele Guo, Fei Pei, Ketao Zhong   +3 more
wiley   +1 more source

SMURF1 Regulates CTCF-HOXA10 Axis and Promotes Tumor Progression in Nasopharyngeal Carcinoma. [PDF]

Cancer Sci
Jin Y, Zhang T, Wu Z, Liang Y, Jiang Y, Yu G.   +5 more
europepmc   +1 more source

Oral Spermidine Supplementation Preserves Submandibular Gland Function After Radiotherapy: Mechanistic Insights and Use in a Phase II Randomized Clinical Trial

MedComm, Volume 7, Issue 8, August 2026.
Radiotherapy‐induced xerostomia severely impairs quality of life. Integrated multiomics, organoids, murine models, and a randomized Phase II trial identified spermidine as a key radiation‐responsive metabolite. Oral spermidine preserved salivary gland function, maintained acinar cell integrity through Golgi‐mediated posttranslational modifications ...
Yu Min, Kun Gao, Yingtong Liu, Lei Dai, Xingchen Peng   +4 more
wiley   +1 more source

Antibody–Drug Conjugates and Peptide–Drug Conjugates: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 8, August 2026.
The graphic summarizes the design principles, intracellular trafficking, clinical progress, challenges, and future directions of antibody–drug conjugates (ADCs) and peptide–drug conjugates (PDCs). ADCs consist of a tumor‐targeting antibody, a chemical linker, and a potent payload, whereas PDCs use peptide ligands to deliver cytotoxic, radionuclide, or ...
Ruxi Zheng, Shuiquan Li, Zhigang Zhang, Mengke Niu, Jing Fei, Jiaojiao Zhang, Jianwei Zhou, Kongming Wu, Ming Yi, Tianye Li   +9 more
wiley   +1 more source

Therapeutic Vaccines for Head and Neck Squamous Cell Carcinoma and Nasopharyngeal Carcinoma. [PDF]

Vaccines (Basel)
Baliton M, Alfatlawi D, Attarian S, Nabar R, Villaflor V.   +4 more
europepmc   +1 more source

Nucleotide Metabolism in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
Nucleotide metabolism, including de novo synthesis, salvage pathways, and catabolism, when dysregulated contributes to cancer, immune disorders, metabolic and urological diseases, and radiation injury. Metabolites such as adenosine, cGAMP, NAD, and cAMP and enzymes like RNR are promising therapeutic targets and biomarkers.
Xiaoying Zhao, Yiyu Zeng, Yike Xu, Shu Rao, Mouna Khouchani, Hassna Soummane, Jingyi Li, Rui Liu   +7 more
wiley   +1 more source