Results 231 to 240 of about 73,649 (308)

Metabolic Regulation of Immune Responses: Molecular Mechanisms, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 6, June 2026.
FBP1 loss drives immune evasion and therapy resistance by enhancing glycolysis, STAT3 activation, and PD‐L1 expression, leading to T cell exhaustion and NK cell inhibition. FBP1 restoration, via LNP‐mRNA or epigenetic modulation, reverses these immunosuppressive effects, reactivates cytotoxic T cells, promotes M1 macrophage polarization, and enhances ...
Chunwei Li, Ziqiang Liu, Dezheng Kong, Zhengze Li, Yiming Yan, Yanyu Dong, Lili Zhu, JiaNing Cao, Zhirui Fan, Gautam Sethi, Lifeng Li   +10 more
wiley   +1 more source

SMURF1 Regulates CTCF-HOXA10 Axis and Promotes Tumor Progression in Nasopharyngeal Carcinoma. [PDF]

Cancer Sci
Jin Y, Zhang T, Wu Z, Liang Y, Jiang Y, Yu G.   +5 more
europepmc   +1 more source

The Dual Role of Autophagy in Cancer: Mechanisms and Therapeutic Strategies

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Autophagy is a conserved cellular process degrading dysfunctional organelles and protein aggregates to maintain cell homeostasis, and it exhibits context‐dependent duality in cancer. Autophagy functions as a critical tumor‐suppressive mechanism by preventing DNA damage and mutation during tumor initiation.
Xiang‐Zheng Gao, Yuheng Qin, Haoyu Wan, Guang Lu, Han‐Ming Shen   +4 more
wiley   +1 more source

Impact of ComBat harmonization on MRI radiomic-analysis of nasopharyngeal carcinoma: a dual-center study. [PDF]

Front Oncol
Pei W, Wei Y, Lai P, Mao L, Huang X, Su D, Liao H, Lu S.   +7 more
europepmc   +1 more source

Targeting EZH2 in Cancer: From Molecular Mechanisms to Clinical Translation

MedComm – Oncology, Volume 5, Issue 2, June 2026.
The abnormal overexpression or gain‐of‐function mutations of EZH2 play a significant role in cancer occurrence and progression, highlighting the importance and potential of EZH2 as a cancer biomarker. Therefore, screening for effective and safe small‐molecule inhibitors, degraders, and natural compounds targeting EZH2 through preclinical cancer models ...
Xi Zhong, Jieni Li, Mingxuan Pan, Xiaoxue Ke, Hongjuan Cui   +4 more
wiley   +1 more source

Downregulation of miR-10b-3p by EBV promotes tumor growth and metastasis via ITGAV in nasopharyngeal carcinoma. [PDF]

PLoS Pathog
Zhang Y, Shi Y, Zou Y, Li L, Dian Z, Chen Y, Zhao H, Wang J, Sun Y.   +8 more
europepmc   +1 more source

Risk Factors and Predictive Model for Otitis Media With Effusion After Radiotherapy in Nasopharyngeal Carcinoma: A Retrospective Study

World Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 12, Issue 3, Page 305-315, June 2026.
ABSTRACT Objective To investigate the impact of different radiation fields on the risk of otitis media with effusion (OME) in nasopharyngeal carcinoma (NPC) patients and to develop a nomogram to identify high‐risk patients after radiotherapy. Methods Clinical data were collected from 170 NPC patients who underwent radiotherapy at Peking Union Medical ...
Zhi‐Jin Han, Shu Wang, Shu‐Yi Wang, Zhi‐Yuan Wu, Meng‐Yao Xie, Chen Li, Qi Tang, Xiao‐Wu Huang, Yu‐Liang Sun, Xin‐Hai Wang, Ke Hu, Hua Yang   +11 more
wiley   +1 more source

Navigating fatherhood and identity reconstruction among fathers with nasopharyngeal carcinoma: A qualitative study. [PDF]

Asia Pac J Oncol Nurs
Su X, Peng Z.
europepmc   +1 more source

Oral Health—Head and Neck Cancers: Addressing Confounding Through Negative Control and Quantitative Bias Analyses

Community Dentistry and Oral Epidemiology, Volume 54, Issue 3, Page 347-353, June 2026.
ABSTRACT Objectives While there are plausible biological explanations for the association between oral health and head and neck cancers (HNC), existing studies have yielded conflicting results. A key concern is that these associations are influenced by mediators, unmeasured risk factors, and biases. To address this, a negative control exposure was used
P. K. Elango, B. Nicolau, N. Farsi, A. V. Grant, M. C. Rousseau, S. Madathil   +5 more
wiley   +1 more source

Unraveling the potential of sodium butyrate in combating nasopharyngeal carcinoma: a narrative review. [PDF]

Ann Med Surg (Lond)
Peng LP, Chen L, He JN, Yin SH.
europepmc   +1 more source