GERD and Upper Aerodigestive Tract Cancer Risk: A Systematic Review and Meta‐Analysis
ABSTRACT Objective Gastroesophageal reflux disease (GERD) is highly prevalent, yet its association with upper aerodigestive tract (UADT) cancers beyond esophageal adenocarcinoma remains incompletely defined. This systematic review and meta‐analysis aimed to quantify the risk of specific UADT cancers in individuals with GERD.
Janice Huang +10 more
wiley +1 more source
Circulating Microbial Metabolites Predict Tumor Relapse and Chemotherapy Efficacy in Nasopharyngeal Carcinoma. [PDF]
Li JY +16 more
europepmc +1 more source
Chinese herbal products for nasopharyngeal carcinoma: A population-based registry study
Shih-Ting Tseng +7 more
openalex +1 more source
Unilateral Nasopharyngeal Endoscopic Resection Type III: Technical Notes
The present video case report details technical notes of Nasopharyngeal Endoscopic Resection (NER) Type III, performed for a mucosal melanoma in a 71‐year‐old patient. Key surgical steps—such as achieving optimal exposure, employing Doppler‐guided internal carotid artery localization, and applying vascularized flap coverage—are outlined, demonstrating ...
Carlo Conti +7 more
wiley +1 more source
Targeted Therapy and Immunotherapies in Hepatocellular Carcinoma: Mechanisms and Clinical Studies
The mechanism of multiple signaling pathways and their related targeted inhibitors in HCC. (A) The mechanism of Ras/Raf/MEK/ERK signaling pathway and its related targeted inhibitors; (B) the mechanism of PI3K/AKT/mTOR signaling pathway and its crosstalk with other pathways and its related targeted inhibitors; (C) the mechanism of JAK/STAT signaling ...
Penghui He +9 more
wiley +1 more source
RNA Modifications: Current Understandings and Future Perspectives
Types of RNA modification. We have summarized the currently common types of RNA modifications, including ac4C, m6A, m1A, m5C, m3C, m7G, and ψ, and visually characterized their features through structural formulas. The characteristic structures are marked with a background color different from the background color.
Shiyu Xiao +7 more
wiley +1 more source
Auditory Preservation in Nasopharyngeal Carcinoma: Comparison of Proton and Photon Radiotherapy. [PDF]
Lien KH +11 more
europepmc +1 more source
Intratumoral Microorganisms in Tumors: Current Understanding and Emerging Therapeutic Strategies
Tumors are no longer viewed as sterile but dynamic ecosystems harboring low‐biomass intratumoral microbiota. These microbes, derived from gut, oral cavity, or circulation, shape tumorigenesis and therapy response via core mechanisms: immunomodulation (regulating T cells, macrophages), metabolic reprogramming (SCFAs, indoles, bile acids), chronic ...
Haoling Zhang +8 more
wiley +1 more source
Cutaneous metastasis secondary to nasopharyngeal carcinoma: a case report. [PDF]
Yang Y, Hu YL, Li TH.
europepmc +1 more source
Targeting Tumor Stroma: Current Challenges and Future Directions
Figure 1. Mechanism of ECM reprogramming. Cancer‐associated fibroblasts (CAFs), cancer‐associated macrophages (CAMs), and other mesenchymal cells alter the ECM composition and increase its stiffness by depositing matrix components such as collagen and hyaluronic acid, and secreting cross‐linking agents like lysyl oxidase homolog 2 (LOXL2).
Siwei Wang +7 more
wiley +1 more source

