Results 241 to 250 of about 73,649 (308)

Tumor‐Specific Success Probabilities and Factors Associated With Phase III Trials in Oncology Drug Development

Clinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT Despite advances in novel therapeutic modalities, such as molecularly targeted agents and immunotherapies, the probability of success in Phase III oncology trials remains low. This study quantitatively characterized success probabilities of Phase III trials in oncology drug development and evaluated the factors associated with trial success ...
Keiko Yamamoto, Aya Iwase, Hideki Maeda
wiley   +1 more source

Proteomics Combined with N-Glycoproteomics to Explore the Pathogenesis of Nasopharyngeal Carcinoma. [PDF]

J Proteome Res
Chen X, Li Z, Ling H, Zhou Y, Wu Y, Lin Q.   +5 more
europepmc   +1 more source

Decoding the Oncogenic Role of GNG10 in Colorectal Cancer: A Non‐Canonical Wnt Pathway–Driven Mechanism

Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Guanine nucleotide‐binding protein gamma 10 (GNG10) is implicated in various biological processes, yet its specific oncogenic role in colorectal cancer (CRC) remains poorly defined. This study aimed to elucidate the expression patterns, biological functions, and underlying mechanisms of GNG10 in CRC progression.
Xitao Zhang, Yuting Tang, Xuexiao Li, Ou Li, Yaoqian Liu, Jianping He, Tianlai Liu   +6 more
wiley   +1 more source

Overexpression of FOXO1 may suppress proliferation and migration and correlate with tumor immune cells in nasopharyngeal carcinoma. [PDF]

Transl Cancer Res
Yu P, Wei W, Wu G, Liu X, Qin S, Ma H, Feng L, Cai Y, Liu L.   +8 more
europepmc   +1 more source

ZNF844 Suppresses Invasion and Metastasis in Nasopharyngeal Carcinoma by Inhibiting the PI3K-AKT Signaling Pathway. [PDF]

Cancer Sci
Xu J, Chen C, Zhang B, Liao S, Mo Y, Zhang R, Kong X, Jiang W.   +7 more
europepmc   +1 more source

Radiosensitivity Enhancement by Combined Treatment of Nimotuzumab and Celecoxib on Nasopharyngeal Carcinoma Cells [Retraction]. [PDF]

Drug Des Devel Ther
europepmc   +1 more source

High VRK2 expression level predicts unfavorable survival outcomes in nasopharyngeal carcinoma. [PDF]

BMC Cancer
Yuan CH, Ke HL, Jhan JH, Chu TH, Chang YT, Yang CC, Yeh CF, Lin HH, Chang SL, Tseng CC.   +9 more
europepmc   +1 more source

Prognostic factors and treatment outcomes in nasopharyngeal carcinoma patients with liver metastasis. [PDF]

Am J Transl Res
Liu C, Wang T, Zhou H.
europepmc   +1 more source

Case Report: A case of severe hypotension induced by nimotuzumab in a nasopharyngeal carcinoma patient. [PDF]

Front Immunol
Liu W, Qin P, Xiao F, Sun B.
europepmc   +1 more source

Overcoming chemoresistance in nasopharyngeal carcinoma: minocycline as a mitochondrial translation inhibitor. [PDF]

Discov Oncol
Xiang F, Dai Q, Chen W.
europepmc   +1 more source