Results 231 to 240 of about 99,765 (284)

Shikonin: From Biosynthesis and Pharmacological Mechanisms to Translational Safety and Drug Delivery

ChemBioChem, Volume 27, Issue 21, 12 November 2026.
Shikonin, biosynthesised in Boraginaceae roots from phenylalanine‐derived PHB and isoprenoid GPP, modulates redox balance, cellular stress, signalling pathways, and regulated cell death. Preclinical studies support diverse pharmacological activities, while nanocarriers improve dispersion and delivery.
Namini Joshi, Prabhakar Semwal, Balwant Rawat, Ravendra Kumar, Mozaniel Santana de Oliveira, Nishant Rai, Janhvi Mishra Rawat   +6 more
wiley   +1 more source

Catalytic DNA for Precision Diagnostics: DNAzyme‐Based Approaches to Single‐Nucleotide Polymorphism Detection

ChemBioChem, Volume 27, Issue 21, 12 November 2026.
This review covers DNAzyme sensor architectures for single‐nucleotide polymorphism (SNP) genotyping, including gold nanoparticle (AuNP) and amplification‐assisted formats, and the design rules governing single‐base discrimination. Single‐nucleotide polymorphisms (SNPs) are the most abundant form of human genetic variation and serve as important ...
Marah Alkhalili, Saqer Al Abdullah, Farbod Ebrahimi, Kristen Dellinger   +3 more
wiley   +1 more source

Airborne and Surface Bacteria in ORs: Integration of ASHRAE‐Compliant Ventilation and Active UV‐C Air Treatment

AORN Journal, Volume 124, Issue 5, Page 346-355, November 2026.
ABSTRACT Bacteria in ORs increase surgical site infection risk. The American Society of Heating, Refrigerating and Air‐Conditioning Engineers Standard 170 defines OR ventilation standards, but the added benefit of in‐room supplemental ultraviolet C air treatment remains uncertain.
Linda D. Lee, Isabelle Clark, Matthew Toldy, Conor Donnelly, Haley Hatfield, Kristen Metzger, Kellee Necaise, L. Michelle Cleveland‐Hall, Sarah Bomgaars, Lauren Nemeth, Jennifer McNary Smith, Russell N. Olmsted   +11 more
wiley   +1 more source

Phytochemical Profiling and Anticancer Potential of Ipomoea hederifolia L. Root Extract: LC–MS Characterization and Molecular Docking Insights

Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.
Integrated LC‐HRMS metabolite profiling, cytotoxicity evaluation, and molecular docking revealed the anticancer potential of Ipomoea hederifolia L. root extract through modulation of EGFR‐, ERBB2‐, and MET‐mediated pathways in HepG2 liver cancer cells.
Poonam Joshi, Anjali Tripathi, Sandhya S
wiley   +1 more source

Nasopharyngeal Carcinoma Mimicking Juvenile Nasopharyngeal Angiofibroma in an Adolescent Ghanaian Male: A Diagnostic Pitfall

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Nasopharyngeal carcinoma can mimic juvenile nasopharyngeal angiofibroma in adolescent males on both demographics and imaging; bilateral cavernous sinus involvement and sensorineural hearing loss are atypical for juvenile nasopharyngeal angiofibroma (JNA) and should prompt expedited tissue diagnosis even in settings where biopsy of a presumed ...
Dennis Brempong, Margaret Neizer, Samuel Romeo Hammond, Benedict Takyi   +3 more
wiley   +1 more source

Pneumocoele sinus: Computed tomographic findings and surgical approach in a 2‐year‐old Cob filly

Equine Veterinary Journal, Volume 58, Issue 6, Page 1636-1641, November 2026.
Abstract Background Pneumosinus dilatans and pneumocoele sinus describe abnormal hyperpneumatisation of paranasal sinuses, with the latter being accompanied by thinning of bony walls. Although recognised in human and equine medicine, to the authors' knowledge, this condition's computed tomography (CT) findings and successful surgical approach in horses
Sarah L. Thompson, Manon W. J. Peeters, Gabriel Manso‐Díaz, Andrew R. Fiske‐Jackson   +3 more
wiley   +1 more source

Longitudinal Swallowing and Salivary Changes With CLR 131 and Re‐Irradiation in Recurrent Head and Neck Cancer

Head &Neck, Volume 48, Issue 11, Page 3032-3042, November 2026.
ABSTRACT Background Patients with recurrent head and neck cancer (HNC) often present with severe, persistent dysphagia and xerostomia following prior chemoradiation. Although swallowing impairments and salivary dysfunction have been reported in this population, prior longitudinal studies have not examined changes in salivary composition or how these ...
Jenni Wu, Sara Gustafson, Meredith Hyun, Roxana Alexandridis, Mark Nicosia, Timothy McCulloch, Justine Bruce, Randall Kimple, Nicole Rogus‐Pulia   +8 more
wiley   +1 more source

Randomized Phase II Trial of Consolidation Pembrolizumab After Definitive Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma: KCSG HN19‐09, CONPELAN Study

Head &Neck, Volume 48, Issue 11, Page 3103-3112, November 2026.
ABSTRACT Background The benefit of consolidation programmed cell death protein 1 (PD‐1) blockade after chemoradiotherapy in locoregionally advanced nasopharyngeal carcinoma (NPC) remains unclear. Methods Patients with stages II–IVB NPC were randomized (2:1) to pembrolizumab 200 mg or placebo every 3 weeks for up to 17 cycles after chemoradiotherapy ...
Sang Hoon Chun, Seyoung Seo, Jang Ho Cho, Keon‐Uk Park, Sang‐Cheol Lee, Yong Won Choi, Tak Yun, Seong Hoon Shin, Sung‐Bae Kim, Seungeun Lee, Chang Ho Ahn, Bhumsuk Keam   +11 more
wiley   +1 more source

Nasopharyngeal Carriage of Streptococcus pneumoniae in Healthy Turkish Infants

Journal of Infection, 2008
The aims of this study were to determine nasopharyngeal carriage rates, serotype distribution and antimicrobial resistance patterns of Streptococcus pneumoniae in healthy 0 to 2 year-old infants who live within a rural or urban locale and not attending daycare centers.
Aysu Duyan Çamurdan, Ufuk Beyazova, Nedim Sultân   +2 more
exaly   +5 more sources