Results 101 to 110 of about 386,285 (319)

Liquid Biopsies in Head and Neck Cancers: Recent Developments Across Biofluids, Analytes, and Molecular Features

Head &Neck, EarlyView.
ABSTRACT Background Head and neck cancers (HNCs) are too often diagnosed at advanced stages when outcomes are poor. Additionally, robust tools for the early detection of recurrence remain elusive. These gaps drive interest in so‐called liquid biopsy approaches for HNC detection, prognostication, and surveillance.
Patricia J. Brooks, Scott V. Bratman
wiley   +1 more source

Apoptosis regulators of the Bcl‐2 family play a key role in chemoresistance of cholangiocarcinoma organoids

International Journal of Cancer, EarlyView.
What's New? Poor prognosis in cholangiocarcinoma (CCA) is attributed to late diagnosis and intrinsic chemoresistance. In particular, resistance mechanisms that suppress apoptosis limit the effectiveness of gemcitabine‐based regimens, which remain the standard treatment.
Wunan Mi, Gilles S. van Tienderen, Shaojun Shi, Amy Broeders, Kathryn Monfils, Henk P. Roest, Luc J. W. van der Laan, Monique M. A. Verstegen   +7 more
wiley   +1 more source

Evaluating ChatGPT's recommendations for systematic treatment decisions in recurrent or metastatic head and neck squamous cell carcinoma: Perspectives from experts and junior doctors

International Journal of Cancer, EarlyView.
What's New? While artificial intelligence (AI) can potentially support clinical decision‐making in recurrent head and neck squamous cell carcinoma (HNSCC), its reliability and accuracy require extensive investigation. Here, the performance of ChatGPT‐4 as a decision‐support tool for staging and treatment planning in HNSCC was assessed. The tool was 83%
Danfang Yan, Lihong Wang, Liming Huang, Kejia Cheng, Yu Huang, Yangyang Bao, Xin Yin, Mengye He, Huiyong Zhu, Senxiang Yan   +9 more
wiley   +1 more source

Toxicities in long‐term survivors of head and neck cancer—A multi‐national cross‐sectional analysis

International Journal of Cancer, EarlyView.
What's New? Cancer treatments frequently have toxic effects on the body, and these toxicities may cause long‐term health issues. Here, the authors report the results of a large, international study to evaluate long‐term toxicities of treatment for head and neck cancer (HNC).
Katherine J. Taylor, Cecilie D. Amdal, Kristin Bjordal, Guro L. Astrup, Bente B. Herlofson, Fréderic Duprez, Ricardo R. Gama, Alexandre Jacinto, Eva Hammerlid, Melissa Scricciolo, Femke Jansen, Irma M. Verdonck‐de Leeuw, Giuseppe Fanetti, Orlando Guntinas‐Lichius, Johanna Inhestern, Tatiana Dragan, Alexander Fabian, Andreas Boehm, Ulrike Wöhner, Naomi Kiyota, Maximilian Krüger, Pierluigi Bonomo, Monica Pinto, Sandra Nuyts, Joaquim Castro Silva, Carmen Stromberger, Pol Specenier, Francesco Tramacere, Ayman Bushnak, Pietro Perotti, Michaela Plath, Alberto Paderno, Noa Stempler, Maria Kouri, Vincent Grégoire, Silke Tribius, Susanne Singer, on behalf of the EORTC Quality of Life Group and the EORTC Head and Neck Group   +37 more
wiley   +1 more source

[Acute bilateral ophthalmoplegia and nasopharyngeal neoplasms].

Anales de medicina interna (Madrid, Spain : 1984), 1997
The cranial nerves, due to its location, are not infrequently involved in the nasopharyngeal neoplasm evolutionary course. In this paper we describe two cases in which the neoplastic infiltration in both cavernous sinuses brought the appearance of an acute bilateral ophthalmolegia on.
L, Marcos Martínez, M, Aparicio Blanco, I, Gil González, M, Martín-Luquero Ibáñez, J C, Martín Escudero, N, Freijanes Otero   +5 more
openaire   +1 more source

Applications of artificial intelligence‐driven microfluidics in medical laboratory science

Interdisciplinary Medicine, EarlyView.
The advancements in microfluidics and artificial intelligence are transforming the landscape of Medical Laboratory Science. This article systematically reviews the approaches and applications of AI‐driven microfluidics for analyzing cells, bacteria, nucleic acids, proteins, viruses, and cancer, while also addressing current challenges and proposing ...
Qingyang Jiang, Qiaohui Mo, Chenchen Ge, Wangjing Li, Jingwen Mai, Yao Chen, Ying Liu, Xiaoyan Deng, Zifeng Yang, Dou Wang   +9 more
wiley   +1 more source

Patient‐derived xenograft models in pan‐cancer: From bench to clinic

Interdisciplinary Medicine, EarlyView.
Abstract Patient‐derived xenograft (PDX) models provide a robust preclinical platform that preserves the genetic and phenotypic heterogeneity of patient tumors while mirroring their tumor genetic characteristics, which retain malignant cells and the tumor pathological structure, making them valuable for studying tumor progression and developing ...
Jiatong Li, Ao Gu, Nannan Tang, Gokhan Zengin, Meng‐Yao Li, Yingbin Liu   +5 more
wiley   +1 more source

Atypical presentation of antrochoanal polyp in a child

The Turkish Journal of Pediatrics, 2011
Antrochoanal polyp is a benign, solitary polypoid lesion arising from the edematous mucosa of the maxillary sinus and extending through the maxillary ostium into the nose. In children, it constitutes 33% of all nasal polyps.
Leyla Kansu, Erdinç Aydin
doaj  

Recent advances in isothermal amplification techniques coupled with clustered regularly interspaced short palindromic repeat/Cas systems

Interdisciplinary Medicine, EarlyView.
Abstract Isothermal amplification (IA) techniques have emerged as promising alternatives to polymerase chain reaction (PCR), enabling rapid and efficient nucleic acid amplification at constant temperatures. Meanwhile, clustered regularly interspaced short palindromic repeat (CRISPR)/Cas‐based technology has revolutionized molecular diagnostics by ...
Miao Liu, Yajun Hou, Yuhang Cheng, Ziyun Li, Jiawei Zeng, Li Li, Jinyong Luo, Bo Shen   +7 more
wiley   +1 more source

Low albumin-to-creatinine ratios (ACR) are associated with poor outcomes in cancer patients

BMC Cancer
Background The albumin-to-creatinine ratio (ACR) is known to predict prognosis in liposarcoma patients, but its role in other tumors remains unclear. This study aimed to evaluate the prognostic relationship between ACR and common solid tumors.
Hong Zhao, Xiangrui Li, Xiaoyue Liu, Chenan Liu, Xin Zheng, Yue Chen, Jinyu Shi, Qiteng Liu, Zhaoting Bu, Hanping Shi   +9 more
doaj   +1 more source