Results 141 to 150 of about 30,002 (370)

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

Exploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu, Guiyu Dai, Yanyan Chen, Lihua Tan, Hanqing Liu, Meiwan Chen   +5 more
wiley   +1 more source

On tumor development: fractional transport approach [PDF]

arXiv, 2004
A growth of malignant neoplasm is considered as a fractional transport approach. We suggested that the main process of the tumor development through a lymphatic net is fractional transport of cells. In the framework of this fractional kinetics we were able to show that the mean size of main growth is due to subdiffusion, while the appearance of ...
arxiv  

LARGE EXTRANODAL NON HODGKIN'S LYMPHOMA OF THE PARAPHARYNGEAL SPACE [PDF]

, 2013
Of all head and neck tumors, 0.5% to 0.8% of them are localized in the parapharyngeal space. Non-Hodgkin’s lymphomas in this site are extremely rare. There are described in literature as either isolated cases or small series of tumors of that space.
Aleric, Zorica, Bauer, Vladimir
core   +1 more source

Incidental Finding of an Extensive Oropharyngeal Mass in Magnetic Resonance Imaging of a Patient With Temporomandibular Disorder: A Case Report [PDF]

, 2016
In this report, we describe the incidental finding of an oropharyngeal mass in a patient who presented with a chief complaint of temporomandibular pain. The patient was initially evaluated by an otorhinolaryngologist for complaints of headaches, earache,
Akintoye, Sunday O., Mupparapu, Mel, Omolehinwa, Temitope T.   +2 more
core   +3 more sources

Explainable machine learning for neoplasms diagnosis via electrocardiograms: an externally validated study [PDF]

arXiv
Background: Neoplasms remains a leading cause of mortality worldwide, with timely diagnosis being crucial for improving patient outcomes. Current diagnostic methods are often invasive, costly, and inaccessible to many populations. Electrocardiogram (ECG) data, widely available and non-invasive, has the potential to serve as a tool for neoplasms ...
arxiv  

Vision Changes After Head and Neck Cancer Treatment

Head &Neck, EarlyView.
ABSTRACT Background Literature about ocular toxicity after head and neck cancer (HNC) treatment is scarce. This study aimed to describe visual function and ocular symptoms among HNC patients. Methods The study used a cross‐sectional design. Two surveys, The National Eye Institute Visual Functioning Questionnaire (NEI‐VFQ) and an Ocular Symptom Scale ...
Hsiao‐Lan Wang, Megan Heskett, Peng Li, Laura Dreer, David Vance, Susan McCammon, Kailei Yan, Amanda Elliott   +7 more
wiley   +1 more source

Epidemiology of childhood and adolescent cancer in Bangladesh, 2001-2014 [PDF]

, 2016
Background: Cancer burden among children and adolescents is largely unknown in Bangladesh. This study aims to provide a comprehensive overview on childhood and adolescent cancers and to contribute to the future strategies to deal with these diseases in ...
Begum, M. (Mamtaz), Choudhury, S. (Salma), Ferdous, S. (Shameema), Hossain, M.S. (Mohammad Sorowar), Kabir, S. (Shahinur), Karim, S. (Sabina), Karim-Kos, H.E. (Henrike), Khan, A. (Asaduzzaman), Khan, Z.J. (Zohora Jameela), Mian, M.M. (Md Mahmuduzzaman), Sarker, H.K. (Humayun Kabir)   +10 more
core   +2 more sources

Differences in PD‐L1, PD‐L2, and EGFR Expression Between Naive and Recurrent Tumors in Patients With Head and Neck Squamous Cell Carcinoma: A Retrospective Study

Head &Neck, EarlyView.
ABSTRACT Background The efficacy of anti‐PD‐1 and EGFR therapies for head and neck squamous cell carcinoma (HNSCC) can be predicted using various markers; however, the stability of these markers remains unclear. Methods In this retrospective study, laboratory findings and tissue expression of PD‐L1, PD‐L2, and EGFR were analyzed in 79 paired naive and ...
Ryosuke Sato, Takahiro Inoue, Risa Wakisaka, Hiroki Komatsuda, Michihisa Kono, Hidekiyo Yamaki, Kenzo Ohara, Takumi Kumai, Akemi Kosaka, Takayuki Ohkuri, Toshihiro Nagato, Kan Kishibe, Hiroya Kobayashi, Miki Takahara   +13 more
wiley   +1 more source

Classification of Nasopharyngeal Cases using DenseNet Deep Learning Architecture [PDF]

arXiv
Nasopharyngeal carcinoma (NPC) is one of the understudied yet deadliest cancers in South East Asia. In Malaysia, the prevalence is identified mainly in Sarawak, among the ethnic of Bidayuh. NPC is often late-diagnosed because it is asymptomatic at the early stage.
arxiv  

Sinonasal (Schneiderian) Tumors in the Temporal Bone: Case Series and Systematic Review. [PDF]

BACKGROUND: Neoplasms derived from the sinonasal epithelium are a rare finding in the temporal bone, and their origins are controversial. PURPOSE: To review the characteristics of sinonasal epithelial (previously known as Schneiderian) tumors occurring ...
Deng, Francis, El-Sayed, Ivan, Glastonbury, Christine, Juliano, Amy, Jung, David, Khan, Nabeeha, Sadow, Peter, Wu, Xin Cynthia   +7 more
core   +1 more source