Results 171 to 180 of about 386,285 (319)

The impact of Foxp3+ regulatory T‐cells on CD8+ T‐cell dysfunction in tumour microenvironments and responses to immune checkpoint inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy, inducing durable remissions in responding patients. However, they are associated with variable outcomes, spanning from disease hyperprogression to complete responses with the onset of immune‐related adverse events.
Mikhaël Attias, Ciriaco A. Piccirillo
wiley   +1 more source

Comprehensive Update on Implants in Patients With Head and Neck Cancer (2021–2024): Systematic Review and Meta‐Analysis of the Impact of Radiotherapy and Chemotherapy on Implant Survival

open access: yesClinical Oral Implants Research, EarlyView.
ABSTRACT Objectives This study aimed to investigate implant outcomes in patients with head and neck cancer undergoing radiotherapy or chemotherapy by incorporating the latest research findings. Methods The present review was conducted to update the focused question: What is the survival rate of implants placed in patients with head and neck cancer ...
Shengchi Fan   +5 more
wiley   +1 more source

Research Advances of the Autophagy‐Regulated Radiosensitivity

open access: yesCell Proliferation, EarlyView.
Autophagy plays a dual role in regulating cellular radiosensitivity in radiotherapy (RT). We discuss the mechanisms by which autophagy promotes survival and growthsuppression by modulating radiosensitivity. It also outlines some frontier autophagy‐targeted radiotherapies. ABSTRACT Autophagy is an evolutionarily conserved process of cell self‐catabolism
Hanyue Liu   +7 more
wiley   +1 more source

Gastric microbiota‐specific signatures in adults with obesity and Helicobacter pylori‐negative gastritis

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
Abstract Background The role of the gastric microbiome in the pathophysiology of gastritis beyond Helicobacter pylori (HP) infection is poorly understood and has remained unexplored in patients with obesity. The aim of this study was to analyse gastric mucosa‐associated microbiota in patients with obesity and nonatrophic chronic gastritis in the ...
José Ignacio Martínez‐Montoro   +7 more
wiley   +1 more source

Pediatric Versus Adult Nasopharyngeal Cancer in Diffusion-Weighted Magnetic Resonance Imaging. [PDF]

open access: yesCancers (Basel)
Crasnean E   +12 more
europepmc   +1 more source

Inflammation and epithelial–mesenchymal transition in a CFTR‐depleted human bronchial epithelial cell line revealed by proteomics and human organ‐on‐a‐chip

open access: yesThe FEBS Journal, EarlyView.
Proteomic analysis of cystic fibrosis transmembrane conductance regulator knockout (CFTR‐KO) clones of 16HBE14o‐ cells showed altered pathways linked to inflammation, polymorphonuclear leukocyte (neutrophil) recruitment, and epithelial–mesenchymal transition.
Domenico Mattoscio   +19 more
wiley   +1 more source

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