Results 181 to 190 of about 53,403 (325)

Crosstalk Between Intratumoral Microbes and Tumor Immunity: Implications for Tumor Therapy

open access: yesCancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Emerging studies indicate that microbes are present in tumor cells and immune cells. Intratumoral microbiota (ITM) constitute an important component of the tumor immune microenvironment (TIME) and have an important impact on tumor progression and treatment. Objective Through the general elaboration of ITM represented by bacteria and
Fengxue Li   +13 more
wiley   +1 more source

Single‐cell sequencing for cancer precision medicine: From mechanism discovery to diagnosis and therapeutics

open access: yesClinical and Translational Discovery, Volume 6, Issue 1, February 2026.
Single‐cell sequencing overcomes bulk sequencing limitations, enabling high‐resolution multi‐omics analysis at the single‐cell level. It reveals tumour heterogeneity, identifying key subpopulations and tumour microenvironment interactions driving progression and resistance.
Yue Zhao   +8 more
wiley   +1 more source

GPR183‐mediated activation of PI3K is a potential biomarker for immunotherapy in lung cancer

open access: yesClinical and Translational Discovery, Volume 6, Issue 1, February 2026.
Anti‐PD1 treatment and PI3Kγ inhibition had remarkable therapeutic performance on CD4+ Tcm and CD4+ Tn in lung cancer through potential regulation of PI3K pathway with participation of GPR183. Abstract Background As one of commonly used immune checkpoint inhibition therapies, PD1 monoclonal antibodies exhibit a promising cancer immunotherapy approach ...
Ling Ye   +9 more
wiley   +1 more source

Discontinuation of immunotherapy and its effect on prognosis in recurrent or metastatic nasopharyngeal carcinoma patients: a retrospective analysis. [PDF]

open access: yesCancer Immunol Immunother
Peng Y   +11 more
europepmc   +1 more source

deltaHED predicts survival and immune evasion in PD‐1 blockade therapy: A multi‐cohort study across three cancer types

open access: yesClinical and Translational Medicine, Volume 16, Issue 2, February 2026.
deltaHED predicts survival and immune evasion in PD‐1 blockade therapy: a multi‐cohort study across three cancer types. deltaHED quantifies germlinesomatic HLA‐I divergence and predicts survival and immune evasion in PD‐1 blockade therapy. Across nasopharyngeal carcinoma, melanoma, and esophageal squamous cell carcinoma, high deltaHED is associated ...
Jianying Xu   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy