Results 181 to 190 of about 386,285 (319)

The protease ADAMTS5 controls ovarian cancer cell invasion, downstream of Rab25

open access: yesThe FEBS Journal, EarlyView.
Metastatic progression is characterised by extensive remodelling of the extracellular matrix, primarily mediated by secreted proteases, including ADAMTS family members. Rainero and colleagues found that the small GTPase Rab25 promoted the expression of ADAMTS5 in ovarian cancer cells through the activation of the NF‐κB signalling pathway.
Shengnan Yuan   +7 more
wiley   +1 more source

Principal mechanisms of extracellular matrix‐mediated cell–cell communication in physiological and tumor microenvironments

open access: yesThe FEBS Journal, EarlyView.
Intracellular communication controls the processing of generated signals so that every cell type can successfully respond. The extracellular matrix (ECM) is a fundamental regulator of cell communication and signaling through the strict orchestration and functions of its bioactive components.
Zoi Piperigkou   +6 more
wiley   +1 more source

Multidisciplinary Management of an Anterior Skull Base Teratoma in a Neonate. [PDF]

open access: yesPlast Reconstr Surg Glob Open
Allison SG   +5 more
europepmc   +1 more source

Ubiquitination dynamics in human tumour viruses: Viral infection, oncogenesis and antiviral therapy

open access: yesThe FEBS Journal, EarlyView.
The ubiquitin system is essential for cellular homeostasis and regulates many processes. Viruses, including oncogenic ones, exploit or evade this system to survive and replicate. This review explores how human tumour viruses manipulate the ubiquitination system to complete their life cycle, evade immunity and promote cancer.
Oscar Trejo‐Cerro   +2 more
wiley   +1 more source

Sex Differences in Health‐Related Quality of Life in Patients With Head and Neck Cancer—A Prospective Study

open access: yesInternational Journal of Dental Hygiene, EarlyView.
ABSTRACT Objective To analyse sex differences in health‐related quality of life (HRQL) before, during and up to 3 months posttreatment of head and neck cancer, and to examine the importance of salivary secretion rate for HRQL posttreatment. Methods Patients were recruited before starting curative oncologic treatment.
Niklas Bohm   +4 more
wiley   +1 more source

Efficacy of Metastasectomy for Metastatic Bladder Cancer: A Systematic Review and Meta‐Analysis

open access: yesInternational Journal of Urology, EarlyView.
ABSTRACT Objectives It has been proposed that metastasectomy may cure some patients with a single metastasis. Hence, we considered it necessary to clarify the role of metastasectomy for metastatic bladder cancer (BCa). Methods We conducted a systematic review of published reports on the efficacy of metastasectomy for different sites of BCa metastasis ...
Junjie Ji   +3 more
wiley   +1 more source

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