CD20⁺FCRL4⁺ B cells in nasopharyngeal carcinoma actively cross‐present exogenous tumor antigens via MHC‐I, enhancing CD8⁺ T‐cell activation, memory formation, and cytotoxicity. IFNγ‐driven WDFY4 upregulation facilitates this process. These findings reveal an unconventional B‐cell–mediated antitumor mechanism and indicate potential relevance to ...
Benjian Zhang +17 more
wiley +1 more source
Diagnostic and prognostic value of EphB2 in nasopharyngeal carcinoma. [PDF]
Huang Q +7 more
europepmc +1 more source
Droplet Digital CRISPR for Nucleic Acid Detection
This review outlines recent advances in droplet digital CRISPR technology for nucleic acid detection, combining CRISPR specificity with droplet digital‐based absolute quantification. It summarizes core principles, amplification‐assisted and amplification‐free strategies, and representative DNA and RNA biomarker applications.
Yang Zhang +4 more
wiley +1 more source
HELLS inhibits autophagy‑dependent ferroptosis in nasopharyngeal carcinoma by modulating the Nrf2/HO‑1/GPX4 pathway. [PDF]
Jin C +5 more
europepmc +1 more source
ABSTRACT Background Smoking and alcohol drinking are established causes of head and neck cancer (HNC), yet their combined effect and variation by anatomic sub‐site remain incompletely defined. Methods We followed 5,985,244 Korean adults (≥ 30 years) who attended National Health Insurance health screening in 2002–2003 until 31 December 2019.
Eunjung Park +5 more
wiley +1 more source
Identification of hub genes and construction of a survival prediction model for patients with nasopharyngeal carcinoma. [PDF]
Zhu J, Feng Y, Zhu Z, Chen Y, Tang CE.
europepmc +1 more source
ABSTRACT Cancer was the second leading cause of death worldwide in 2018 according to WHO. The disease burden continues to grow and has tremendous impacts on families and healthcare systems. Cancer‐related fatigue is one of the most distressing symptoms experienced by cancer patients and has adverse impacts on the patients' quality of life and ...
Benjamin K. K. Lau +3 more
wiley +1 more source
Bioinformatics identification of adenosylhomocysteinase (AHCY) as a regulator of ferroptosis in nasopharyngeal carcinoma cells via the Hippo-Yes-associated protein (Hippo-YAP) pathway. [PDF]
Zheng H, Wang X, Chen Q.
europepmc +1 more source
Lack of De‐Intensification Models for Female Head and Neck Cancer Patients With Favorable Prognosis
ABSTRACT Purpose The prognostic relevance of gender in head and neck cancer is often neglected. In contrast, the more favorable prognosis of human papillomavirus (HPV)‐associated oropharyngeal squamous cell carcinoma (OPSCC) is well recognized, and de‐escalation strategies are increasingly being tested in clinical trials.
J. M. Vahl +7 more
wiley +1 more source
Synergistic carcinogenesis of the nasopharyngeal microbiome and Epstein-Barr virus: mechanisms of metabolic reprogramming and immune evasion. [PDF]
Shen S, Li J, Zheng S, Cui X, Gou X.
europepmc +1 more source

