Results 241 to 250 of about 51,742 (351)

Dosimetric comparison of intensity‐modulated proton therapy and photon‐based radiotherapy for skull base tumors

Journal of Applied Clinical Medical Physics, Volume 26, Issue 10, October 2025.
Abstract Objective To compare dosimetric differences between intensity‐modulated proton therapy (IMPT) and photon‐based radiotherapy (VMAT/IMRT) in the treatment of skull base tumors, focusing on target coverage and organ‐at‐risk (OAR) sparing. Methods All patients with skull base tumors who underwent proton therapy between December 2021 and August ...
Yuanyuan Wang, Jiajun Zheng, Lei Liu, Yuxiang Wang, Tengfei Long, Ming Liu, Jin Gao, Hsiao‐ming Lu   +7 more
wiley   +1 more source

Short-course PD-1 blockade in locally advanced nasopharyngeal carcinoma: a phase II randomized trial protocol (Tori-013). [PDF]

Front Immunol
Jia H, Wang J, Zhang L, Li H, Du Y, Luo W, Wei Z, Wang X, Wang W.   +8 more
europepmc   +1 more source

Evaluation of a novel quantitative multiparametric MR sequence for radiation therapy treatment response assessment

Journal of Applied Clinical Medical Physics, Volume 26, Issue 10, October 2025.
Abstract Background Multiparametric MRI has shown great promise to derive multiple quantitative imaging biomarkers for treatment response assessment. Purpose To evaluate a novel deep‐learning‐enhanced MUlti‐PArametric MR sequence (DL‐MUPA) for treatment response assessment for brain metastases patients treated with stereotactic radiosurgery (SRS) and ...
Yuhao Yan, R. Adam Bayliss, Adam R. Burr, Andrew M. Baschnagel, Brett A. Morris, Florian Wiesinger, Jose de Arcos Rodriguez, Carri K. Glide‐Hurst   +7 more
wiley   +1 more source

Early circulating EBV-DNA clearance predicts enhanced short-term treatment response and survival benefit in locally advanced nasopharyngeal carcinoma. [PDF]

BMC Cancer
Lu X, Zhu L, Tan B, Liang Z, Chen K, Huang S, Li L, Zhu X.   +7 more
europepmc   +1 more source

Heterogeneity Landscape of Circulating Tumor Cells in Clinical Utility

Advanced Therapeutics, Volume 8, Issue 10, October 2025.
This study reports the heterogeneity spectrum of circulating tumor cells. The factors involved in the spectrum promote CTCs to overcome barriers in the metastatic cascade but impact the clinical outcome of cancer patients. In summary, the heterogeneities in association with CTCs ultimately reduce patient survival and facilitate increasing mortality of ...
Md Kowsar Alam, Lu Yanjun, Bee Luan Khoo, Tongxu Si, Heng Zou, Mengsu Yang   +5 more
wiley   +1 more source

HMMR mediates progression of nasopharyngeal carcinoma by inhibiting FAM83D ubiquitination and activating beta-catenin signaling pathway. [PDF]

Sci Rep
Zhong F, Lu T, Li M, Li D, Yuan A, Luo H, Wang J, Zhang L, Huang K, Su Y, Chen J, Dong Q, Wang J, Liu Z, Huang C, Gong X, Xiong X, Li J.   +17 more
europepmc   +1 more source

PLoS One [PDF]

, 2012
Alles, J., Barth, S., Cogliatti, S., Dueck, A., Grasser, F., Imig, J., Meister, G., Motsch, N., Reineke, T., Renner, C., Tinguely, M., Zhu, J.   +11 more
core   +1 more source

The TET3/GATA6 Axis Drives Lipid Metabolism and Therapeutic Vulnerabilities in Pancreatic Ductal Adenocarcinoma

Advanced Science, Volume 12, Issue 37, October 6, 2025.
The DNA demethylase TET3 drives lipid metabolic reprogramming in pancreatic ductal adenocarcinoma via a non‐catalytic mechanism. TET3 recruits histone deacetylases to repress GATA6, sustaining lipogenic enzyme expression and ferroptosis resistance.
Shuai Liu, Shaobo Kang, Na Lin, Wenqi Zhang, Shiwen Wang, Yuqing Ren, Xiaofan Ding, Jianxiu Yu, Ruiyu Xie   +8 more
wiley   +1 more source

Differentiating early-stage nasopharyngeal carcinoma from adenoidal hypertrophy via SLC40A1 expression and developing a prognostic model for disease progression. [PDF]

Am J Cancer Res
Wang H, Qi S, Liu C, Qiao Z, Zhang C.
europepmc   +1 more source

Cardiovascular Disease Meets Cancer: Exploring the Epidemiology in China and Homotherapy Targeting Intersectional Mechanisms

Advanced Science, Volume 12, Issue 37, October 6, 2025.
Cardiovascular disease (CVD) and cancer are leading causes of death worldwide, with overlapping risk factors and pathophysiological mechanisms. This review explores shared pathways, including metabolic dysregulation, chronic inflammation, and gut microbiome alterations, highlighting dual‐benefit strategies such as lifestyle modifications and repurposed
Shihan Xiang, Yujie Shan, Shihong Xu, Jing Wang, Meng Luo, Jiaojiao Zhou, Qishan Chen   +6 more
wiley   +1 more source