Results 241 to 250 of about 53,459 (315)

RNA Regulatory Networks: Key Hubs in the Panorama of Cancer and Emerging Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 3, March 2026.
RNA regulatory networks play a crucial role in the initiation and progression of cancer through various modes of RNA interactions. Notably, circulating RNAs have emerged as potential biomarkers, while targeted interventions in RNA regulatory networks facilitate precise therapeutic strategies. ABSTRACT Cancer is a global health challenge. The initiation
Xuan Yin   +9 more
wiley   +1 more source

Clinical Application of Peripheral Blood Biomarkers for Solid Tumors

open access: yesMedComm, Volume 7, Issue 3, March 2026.
Peripheral blood biomarkers provide a minimally invasive, dynamic, and potentially more accurate means to obtain a comprehensive tumor profile. Technologies for detecting them are advancing, and with the help of artificial intelligence, they are being used more and more often for cancer diagnosis, prognostic assessment, and therapeutic monitoring ...
Xinru Tu, Mengyan Tu, Junfen Xu
wiley   +1 more source

Chromatin Accessibility in Cancer: Biological Functions, Mechanisms, Therapeutic Potential, and Future Directions

open access: yesMedComm, Volume 7, Issue 3, March 2026.
Cancer remains the leading cause of mortality worldwide, and drug resistance further underscores the urgent need for innovative therapeutic strategies. Chromatin, a stable yet highly dynamic nucleoprotein complex, serves as the primary carrier of genetic material in eukaryotic cells.
Wentao Xia   +4 more
wiley   +1 more source

Safety and Efficacy of Lucitanib Plus Toripalimab in Advanced Solid Tumors Refractory to Standard Therapies: An Open‐Label, Multicenter, Phase II Study

open access: yesMedComm, Volume 7, Issue 3, March 2026.
Lucitanib plus toripalimab showed manageable safety and encouraging antitumor activity in advanced solid tumors, particularly in PD‐1‐refractory nasopharyngeal carcinoma and recurrent endometrial carcinoma. Clinical responses were observed across subgroups regardless of prior immunotherapy.
Ting Zhou   +24 more
wiley   +1 more source

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