Results 251 to 260 of about 51,742 (351)

Integrating Radiomics and Deep-Learning for Prognostic Evaluation in Nasopharyngeal Carcinoma. [PDF]

Medicina (Kaunas)
Pușcaș IM, Gâta A, Roman A, Albu S, Gâta VA, Irimie A.   +5 more
europepmc   +1 more source

SenExo‐cCCT2 Reprograms Senescence Response and Anti‐Tumor Immunity Following FOLFIRINOX Chemotherapy in Pancreatic Ductal Adenocarcinoma

Advanced Science, Volume 12, Issue 38, October 13, 2025.
This study demonstrates that SenExo‐cCCT2 enables targeted delivery of cCCT2 to pancreatic cancer cells, where it disrupts IPO13‐mediated nuclear translocation of UBC9, impairing SUMOylation‐dependent DNA damage repair and inducing senescence. Senescent tumor cells secrete CXCL10 to recruit CD8⁺ T‐cells while upregulating PD‐L1.
Shuncang Zhu, Yinhao Chen, Hongyi Lin, Jinpeng Lu, Yu Pan, Ge Li, Yongding Wu, Haoxiang Zhang, Xiaoxiao Huang, Yiting Chen, Huangjing Chen, Long Jin, Min Huang, Chengyu Liao, Long Huang, Yifeng Tian, Zuwei Wang, Qiaowei Li, Shi Chen   +18 more
wiley   +1 more source

Global, regional, and national burden and projections to 2050 of occupational carcinogen-attributable nasopharyngeal and laryngeal cancer: a comprehensive analysis from the GBD 2021 study. [PDF]

Front Public Health
Zhang H, Xue R, Kong X, Zhao M, Jin Z.
europepmc   +1 more source

A phase 2A/B randomized trial of metabolic modulators intranasal insulin and empagliflozin for MCI and early AD

Alzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract INTRODUCTION Agents targeting metabolic/vascular disorders are promising candidates to treat Alzheimer's disease (AD) and enhance safety and efficacy of other therapies. METHODS In a 2×2 factorial double‐blinded randomized trial, participants with mild cognitive impairment (MCI), early AD, or who were amyloid positive received intranasal ...
Jennifer M. Erichsen, Thomas C. Register, Courtney Sutphen, Da Ma, Sarah A. Gaussoin, Marc Rudolph, Melissa Rundle, James T. Bateman, Samuel N. Lockhart, Kiran K. Solingapuram Sai, Christopher Whitlow, Suzanne Craft   +11 more
wiley   +1 more source

Effects of non-pharmacological interventions on nutrition and immune status of nasopharyngeal carcinoma patients during chemoradiotherapy: a systematic review and meta-analysis protocol. [PDF]

BMJ Open
Xia L, Hayashi N, Ota E, Qi L, Yan B.
europepmc   +1 more source

Mitochondrial Microproteins: Emerging Regulators in Neurodevelopment and Neurodegeneration

BioEssays, Volume 47, Issue 10, October 2025.
Mitochondrial microproteins have emerged as critical regulators of mitochondrial function. Neurons are highly dependent on mitochondria to sustain their function. Mitochondrial microproteins can be deregulated and can contribute to the pathogenesis of neurodegenerative disorders. Mitochondrial microproteins are involved in neuronal development. However,
Nada Borghol, Sozerko Yandiev, Julien Courchet   +2 more
wiley   +1 more source

Prognostic value of sarcopenia in patients with nasopharyngeal carcinoma: a meta-analysis. [PDF]

Ann Med
Gu X, Shi Y.
europepmc   +1 more source

Characteristics of Posterior Cerebral Circulation in Patients With Intractable Hiccups: A Case Series

Brain and Behavior, Volume 15, Issue 10, October 2025.
This study investigated the potential association between intractable hiccups and cerebrovascular variants. Clinical and imaging data from 230 patients with intractable hiccups were analyzed. The findings revealed that posterior communicating artery (P‐com) deficiency and type e variations of the Circle of Willis (CW) were highly prevalent among ...
Tsukasa Kondo, Teruhiko Terasawa, Hideyuki Nakama   +2 more
wiley   +1 more source

Long-term immune checkpoint inhibitor therapy in a patient with metastatic nasopharyngeal carcinoma: a case report. [PDF]

Front Immunol
Qing D, Lu Z, Lu H.
europepmc   +1 more source

Favorable survival of patients with nasopharyngeal carcinoma associated with metachronous multiple primary cancers: A retrospective study. [PDF]

Oncol Lett
Huang X, Kong Y, Wu T, Meng Z, Kang M.
europepmc   +1 more source