Results 151 to 160 of about 133,869 (230)

Prognostic Value of LINC01140 in Colorectal Cancer and Its Regulatory Effect on Chemotherapy Resistance via miR‐942‐5p/NRXN1

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 11, November 2026.
Targeting the LINC01140/miR‐942‐5p/NRXN1 axis may be able to inhibit CRC progression by simultaneously regulating the functions of tumor cells and CAFs, which might significantly enhance the clinical efficacy of targeted therapy. ABSTRACT Long non‐coding RNAs play a wide role in colorectal cancer (CRC).
Jian Zhao, Songjie Liu, Bing Xu
wiley   +1 more source

Nasopharyngeal Toxæmia and the Examination of Swabs of the Nasopharynx. [PDF]

open access: yesProceedings of the Royal Society of Medicine, 1920
A, Sellers, C P, Lapage
openaire   +2 more sources

Leuprorelin Suppresses Angiogenesis and Malignant Progression in Endometrial Cancer via Downregulation of the ELAVL1/VEGFA Axis

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 11, November 2026.
Mechanistically, leuprorelin downregulates ELAVL1 expression, which in turn destabilizes VEGFA mRNA and decreases VEGFA protein expression. Functional assays demonstrated that this regulatory axis significantly suppressed EC cell proliferation and migration, promoted apoptosis, and inhibited HUVEC tube formation.
NingNing Zhang, Fang Zhao, LiMei Tan
wiley   +1 more source

Pan‐Cancer Landscape of TMEM9 With Experimental Validation in Head and Neck Squamous Cell Carcinoma

open access: yesThe Journal of Gene Medicine, Volume 28, Issue 11, November 2026.
Transmembrane protein 9 (TMEM9) was investigated across cancers using public transcriptomic, clinical, genomic, and immune datasets, followed by functional validation in head and neck squamous cell carcinoma (HNSC). TMEM9 showed cancer‐dependent expression, diagnostic discrimination, prognostic associations, and relationships with immune infiltration ...
Mi Wang   +3 more
wiley   +1 more source

Liquid Biopsy: Past, Present, and Future

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Liquid biopsy has expanded from cancer genotyping to a broader strategy for probing both oncologic and nononcologic conditions through circulating analytes and multilayer molecular readouts. This review traces the field's past, present, and future—summarizing where liquid biopsy is most actionable today, why performance varies across contexts, and ...
Jiachen Liu   +8 more
wiley   +1 more source

The Prognostic Role of CD8+ Tumor‐Infiltrating Lymphocyte Density in Head and Neck Mucosal Melanoma

open access: yesOtolaryngology–Head and Neck Surgery, Volume 175, Issue 5, Page 1084-1091, November 2026.
Abstract Objective To explore the prognostic role of CD8+ tumor‐infiltrating lymphocytes (TIL) density in head and neck mucosal melanoma (HNMM) using an automated, quantitative, immunohistochemistry‐based methodology. Study Design Retrospective cohort study. Setting Single‐institution, tertiary care hospital.
Nicholas K. Fung   +3 more
wiley   +1 more source

Identification of Active Compounds of Centipeda minima for Potentiating Tumor Immunotherapy in Non‐Small Cell Lung Cancer via FANCD2‐cGAS/STING/IFN‐I Signaling Axis

open access: yesPhytotherapy Research, Volume 40, Issue 11, Page 6791-6808, November 2026.
Schematic diagram illustrating the underlying mechanisms by which ECM and its active components activate the FANCD2‐cGAS/STING/IFN‐I signaling axis, thus enhancing the therapeutic efficacy of anti‐PD‐1 in NSCLC. ABSTRACT Activation of cGAS/STING/IFN‐I signaling pathway serves as a potential therapeutic strategy to enhance CD8+ T cells infiltration and ...
Han‐Chen Wang   +9 more
wiley   +1 more source

Clinical Presentation and Immunological Characteristics of Plastic Bronchitis in Children With Severe MPP

open access: yesThe Clinical Respiratory Journal, Volume 20, Issue 11, November 2026.
Plastic bronchitis in children with severe Mycoplasma pneumoniae pneumonia is associated with immune dysregulation and more extensive pulmonary involvement. Fever duration, extent of lung involvement, serum IgM, CD4+/CD8+ ratio, and bronchoalveolar lavage fluid monocyte percentage may serve as early predictors of PB in children with severe Mycoplasma ...
Haojie Wang   +4 more
wiley   +1 more source

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