Managing reactivation of multiple sclerosis during treatment with natalizumab. [PDF]
Lizak N +36 more
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CD56<sup>bright</sup>NK cells are negatively associated with antibody response to vaccination in people with multiple sclerosis on B-cell-depleting therapy. [PDF]
Perkins GB +21 more
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Clinical relevance and predictors of anti-natalizumab antibodies in multiple sclerosis: A real-world retrospective cohort study. [PDF]
Levy M +10 more
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Combining Pembrolizumab and Ofatumumab in Triple-Negative Breast Cancer and Multiple Sclerosis: A Case Report. [PDF]
Iriyama H +13 more
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Refined single-cell profiling captures a CCR5<sup>high</sup> CD4<sup>+</sup> cytotoxic T-cell precursor in multiple sclerosis. [PDF]
van Puijfelik F +17 more
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Use of multiple sclerosis drugs among pregnant individuals with live-birth deliveries in the FDA's Sentinel Distributed Database. [PDF]
Stojanovic D +8 more
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Since it first came to trial, natalizumab (Tysabri) has kept the multiple sclerosis (MS) world in a constant state of flux. Shortly after its initial launch, the appearance of three cases of progressive multifocal leukoencephalopathy (PML), a devastating infection of the CNS caused by the JC virus, resulted in the drug’s withdrawal from the market ...
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The pharmacology, pharmacokinetics, indications, clinical efficacy, adverse effects, drug interactions, and dosage and administration of natalizumab are reviewed.Natalizumab, the first commercially available selective adhesion-molecule inhibitor, is approved as monotherapy for the treatment of patients with relapsing forms of multiple sclerosis (MS ...
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