Results 71 to 80 of about 23,350,035 (239)

Marsabit County Climate Change Action Plan 2023-2027 [PDF]

open access: yes, 2023
Pastoral and agro-pastoral production forms the dominant livelihood in Marsabit County, involving about 95 percent of its population. Major sources of income within this livelihood include sales of livestock, livestock products and crop production which ...

core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Wajir County Climate Change Action Plan 2023-2027 [PDF]

open access: yes, 2023
The Wajir County Climate Change Action Plan presents a strategic framework for addressing the challenges and opportunities posed by climate change in our county.

core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Action Plan

open access: yes, 2012
Sociology Department's Action Plan - Academic Program ReviewSociology Department's Action PlanSociology Department - Academic Program ...
Sociology Department's Action Plan, Academic Program Review
core  

Corrective Action Plan for Corrective Action Unit 562: Waste Systems, Nevada National Security Site, Nevada [PDF]

open access: yes, 2011
This Corrective Action Plan has been prepared for Corrective Action Unit (CAU) 562, Waste Systems, in accordance with the Federal Facility Agreement and Consent Order (1996; as amended March 2010).
National Security Technologies, LLC
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

The national plan to reduce violence against women and their children 2010 – 2022 [PDF]

open access: yes, 2011
Released in 2011, this 12-year national plan was an COAG initiative supported by Commonwealth, state and territory governments working with the community and includeds the first three-year action plan. Over 12 years the National Plan
Council of Australian Governments
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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