Results 141 to 150 of about 22,312,818 (260)

A nationwide study of community- versus facility-based management of malaria in Sierra Leone from 2019 to 2023. [PDF]

Public Health Action
Sillah-Kanu M, Kamara D, Kamara IF, Fofanah BD, Fiona OO, Vandy AO, Kamara ARY, Lahai WK, Owusu H, Zachariah R, Ramsay A, Falama AM, Sesay MA, Lakoh S, Kanu MS, Tejan YS, SorieTuray I, Thomas F, Squire JS.   +18 more
europepmc   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Practical Answers

, 2012
We have been airing “SAMUDAYA KO JIGYASHA RA BIGYA KO JAWAF” (Communities’ enquiries and expert response) radio progamme. When this programme airs live – the enquirers in the communities listen the radio, however, if they miss the programme our focal ...
Practical Action Nepal
core  

Quality improvement package for severe tuberculosis triage in Tamil Nadu, India. [PDF]

Public Health Action
Jeyakumar A, Kalaiselvi S, Nair D, Vijayaprabha R, Gayathri K, Kabir D, Melfha JM, Bhatnagar T, Srinivasan R, Balusamy M, Shanmugasundaram S, Catherine A, Nithya N, Venkateshwar R, Frederick A, Shewade HD.   +15 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Action research on action research: A facilitator’s account

, 2012
This article describes research conducted by a facilitator of a statewide action research network, the Wyoming Teacher Policy Institute (WTPI).
Trent, Allen
core  

Reimagining research equity and beneficial community impact: reflections from the GSK Africa Open Lab inaugural cohort. [PDF]

Glob Health Action
Afrane AKA, Lartey BL, Adegbola A, Mahamar A, Adankwah E, Kering K, Agbo Achimi Abdul JBP, Tumuhamye J, Tukwasibwe S, Etuk V, Traore O.   +10 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Management of Self Harm Presentations to Emergency Department Clinical Programme:Standard Operating Procedure

, 2014
The aim of this clinical programme is to develop a standardised and effective process for the assessment and management of all age groups who present to ED.
National Clinical Programme Office
core