Results 41 to 50 of about 1,210,282 (359)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source

La Grande Collecte 1914-1918 aux Archives nationales

open access: yesIn Situ, 2014
The operation called ‘La Grande Collecte’, the great collection, is an initiative of the French national library aimed at collecting and copying private documents relating to the First World War.
Isabelle Aristide-Hastir   +1 more
doaj   +1 more source

Pedagogical Journeys or Pleasure Trips: Danish Schoolteachers’ Educational Journeys, 1898–1932

open access: yesNordic Journal of Educational History, 2020
In the last decades of the nineteenth and first decades of the twentieth centuries, a wide range of pedagogical ideas were disseminated in Denmark, influencing both primary schooling and everyday school life.
Christian Larsen
doaj   +1 more source

Hydrological summary for the United Kingdom: August 2013 [PDF]

open access: yes, 2013
The monthly summary of hydrological conditions in the United Kingdom is compiled as part of the National Hydrological Monitoring Programme (a joint CEH and BGS enterprise).
Clemas, Sandie   +4 more
core  

A Petition Written by Ricardus Franciscus [PDF]

open access: yes, 2012
This article identifies Ricardus Franciscus as the scribe of Kew, The National Archives, C 49/30/19, a petition seeking the exoneration of the late Duke Humphrey of Gloucester. (d. 1447). The authors provide a palaeographical analysis of the "flamboyant,
Deborah Thorpe, Holly James Maddocks
core   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

Facing natural extremes

open access: yesSjuttonhundratal, 2022
As a consequence of a large-scale volcanic outburst, the Laki eruption in 1783–1784, the focus of the world turned suddenly towards Iceland, a province of the Danish crown.
Margrét Gunnarsdóttir
doaj   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou   +15 more
wiley   +1 more source

Developing named-entity recognition for state authority archives

open access: yesDigital Humanities in the Nordic and Baltic Countries Publications
Named entity recognition (NER) is one of the more common natural language processing tasks, that usually entails the detection of entities like person, location and date from textual data.
Ida Toivanen   +3 more
doaj   +1 more source

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