Results 141 to 150 of about 219,094 (263)

Dissociating role of Bassoon in glutamatergic and dopaminergic neurons in alcohol‐related behaviour and affective state in mice

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Alcohol abuse and affective disorders are severe comorbid psychiatric diseases characterized by impaired brain synaptic transmission. The role of presynaptic scaffolding proteins coordinating presynaptic plasticity and neurotransmitter release, such as Bassoon (Bsn), in the pathogenesis of these disorders remains elusive.
Liubov S. Kalinichenko, Mona Krenbauer, Janosh Isert, Marlon Kamlah, Thorben Tanzer, Hannes Rödel, Tobias Müller, Anil Annamneedi, Enes Yağız Akdaş, Volker Eulenburg, Bernd Lenz, Eckart D. Gundelfinger, Johannes Kornhuber, Anna Fejtova, Christian P. Müller   +14 more
wiley   +1 more source

The prevalence and clinical relevance of cervical abnormalities after an amputation of the cervix as part of prolapse surgery: a cross-sectional study. [PDF]

Arch Gynecol Obstet
van Cooten VV, van Hamont D, Siebers AG, Alcalá L, Bekkers RLM, Speksnijder L.   +5 more
europepmc   +1 more source

Enhancing antitumour response to proteasome inhibitors with inhibitors of insulin‐degrading enzyme, a new molecular vulnerability in multiple myeloma

British Journal of Pharmacology, EarlyView.
Inhibitors of insulin‐degrading enzyme boost PI cytotoxicity through an increased sensitivity of proteasome to PI inhibitors, induction of ISR, DNA damage and Myc down‐regulation. They overcome PI resistance in vitro and induce tumour regression in vivo.
Laetitia Lesire, Rebecca Deprez‐Poulain, Damien Bosc, Florence Leroux, Valerie Landry, Sarah Ourabah, Morgane Tardy, Clara Maillard, Ronan Gealageas, Julie Dumont, Adrien Herledan, Sandrine Warenghem, Manon Cruette, Celine Lenglart, Alexandre Biela, Catherine Piveteau, Eva De Smedt, Catharina Muylaert, Wenguang Liang, Elvira Garcia De Paco, Elina Alaterre, Sara Ovejero, Nicolas Robert, Fabien Delahaye, Wei‐Jen Tang, Peter van Endert, Elke De Bruyne, Jérôme Moreaux, Benoit Deprez   +28 more
wiley   +1 more source

Eleven quick tips for organizing a data cleaning challenge. [PDF]

PLoS Comput Biol
Kal IJ, Smabers LP, von Berg J, Perticari G, van de Meent M, Fokkelman D, Sprangers J, Lannelongue L, Dekkers F.   +8 more
europepmc   +1 more source

Representativeness of the Natura 2000 network for preserving plant biodiversity in the European Union

Conservation Biology, EarlyView.
Abstract The Natura 2000 (N2K) network of protected areas is one of the main tools for area‐based conservation in the European Union (EU), yet its role in preserving plant biodiversity requires better understanding. We examined data kept in the European Vegetation Archive from over 1.2 million vegetation plots and obtained over 14.2 million plant ...
Michele Di Musciano, Piero Zannini, Riccardo Testolin, Francesco Maria Sabatini, Diletta Santovito, Borja Jiménez‐Alfaro, Florian Jansen, Milan Chytrý, Lorenzo Ricci, Emiliano Agrillo, Fabio Attorre, Idoia Biurrun, Gianmaria Bonari, Hans Henrik Bruun, Luigi Cao Pinna, Andraž Čarni, Maria Laura Carranza, Roberto Cazzolla Gatti, Jürgen Dengler, Michele De Sanctis, Úna Fitzpatrick, Anna Rita Frattaroli, Emmanuel Garbolino, Stephan Hennekens, Ute Jandt, Jan Jansen, Zygmunt Kacki, Ilona Knollová, Jonathan Lenoir, Jesper Erenskjold Moeslund, Tomáš Peterka, Nataša Pipenbaher, Duccio Rocchini, Eszter Ruprecht, Solvita Rūsiņa, Urban Šilc, Sonja Škornik, Grzegorz Swacha, Milan Valachovič, Kiril Vassilev, Wolfgang Willner, Alessandro Chiarucci   +41 more
wiley   +1 more source

Regulation of chemicals demands assessment of risks rather than identification of hazards only. [PDF]

Arch Toxicol
Marx-Stoelting P, Ritz V, Herzler M, Kneuer C, Aiello-Holden K, Brescia S, Escher SE, Feustel S, Fritsche E, Gebel J, Kenny EF, Landsiedel R, Sanders P, Schwarz M, Streitz M, Testai E, van Ravenzwaay B, Waetjen W, Wend K, Wilks M, Luch A, Tralau T, Hensel A.   +22 more
europepmc   +1 more source

The International e-Depot: e-Journal Archiving at the national library of the Netherlands.

, 2006
Erik Oltmans
openalex   +1 more source

The disappearance of malaria from Denmark, 1862–1900

The Economic History Review, EarlyView.
Abstract The reason for malaria's disappearance from northwestern Europe in the early twentieth century has long been discussed but remains an unresolved conundrum. This is partially due to a previous focus on the early modern era, and partially because various theories have never been tested against each other.
Mathias Mølbak Ingholt, Maarten van Wijhe, Lone Simonsen, Daniel Weinberger   +3 more
wiley   +1 more source

Cut from the same cloth? investigating the personality of interventional and surgical cardiovascular specialists. [PDF]

Langenbecks Arch Surg
Sier VQ, Verhagen MJ, Zegel M, Schmitz RF, van Rijswijk CSP, van Schaik J, Schmidt EJET, Hamming JF, Schepers A, Wijdh-den Hamer IJ, Burgmans MC, Hjortnaes J, van der Vorst JR, SUPER Consortium.   +13 more
europepmc   +1 more source

Irish regional GDP since independence

The Economic History Review, EarlyView.
Abstract This paper constructs the first long‐run estimates of Irish regional gross domestic product (GDP) over the twentieth century and traces the relative economic performance of Ireland's regions since independence. Using an array of data sources available at a county level, output in agriculture, industry, and services in benchmark census years is
Alan de Bromhead, Seán Kenny
wiley   +1 more source