Results 181 to 190 of about 219,728 (265)

Suppression of Indoleamine 2,3‐Dioxygenase Enhances Immune Responses to the Therapeutic Vaccine for Chronic Hepatitis B

Hepatology Research, EarlyView.
Indoleamine 2,3‐dioxygenase (IDO) activity modulates immune responses to the therapeutic HBV vaccine NASVAC. Genetic or pharmacological suppression of IDO enhanced vaccine efficacy in mice, and lower serum kynurenine levels predicted favorable responses in humans, suggesting IDO as both a therapeutic target and a biomarker.
Yohei Shirakami, Soranobu Ninomiya, Takayasu Ideta, Ayumu Kanbe, Toshihide Maeda, Daisuke Minowa, Daisuke Taguchi, Masaya Kubota, Hiroyasu Sakai, Kenji Imai, Yasuko Yamamoto, Hiroyasu Ito, Kuniaki Saito, Osamu Yoshida, Yoichi Hiasa, Masahito Shimizu   +15 more
wiley   +1 more source

The mix and match approach in primary total hip arthroplasty reveals comparable or lower revision rates to matched components: a systematic review. [PDF]

Arch Orthop Trauma Surg
Leitner L, Postruznik M, Draschl A, Koutp A, Leithner A, Sadoghi P.   +5 more
europepmc   +1 more source

3D virtual histology demonstrates tumour connectivity in spread through air spaces (STAS) of non‐small cell lung cancer

Histopathology, EarlyView.
STAS‐positive lung nodules were analysed using histology, clinical CT, and synchrotron‐based μCT. μCT enables 3D spatial insights of STAS clusters which appear consistently connected to alveolar or vascular structures, suggesting non‐random distribution.
Giulia Saccomano, Francesco Brun, Fulvia Martellani, Cristina Bottin, Stefano Lovadina, Marina Troian, Maria Assunta Cova, Elisa Baratella   +7 more
wiley   +1 more source

Coordinated Return-to-Work model reduces sickness absences after hip or knee arthroplasty: a registry-based study. [PDF]

Arch Orthop Trauma Surg
Kangas P, Pamilo K, Soini S, Hirvonen M, Kervinen V, Kinnunen ML.   +5 more
europepmc   +1 more source

Dysplasia in sessile serrated lesions: frequency, interobserver variability and added value of immunohistochemistry

Histopathology, EarlyView.
Sessile serrated lesions with dysplasia represent a critical step in colorectal carcinogenesis. While routine histologic diagnosis is generally reliable and positive diagnostic trends are observed, subtle dysplastic changes may be overlooked. Targeted use of MLH1 immunohistochemistry provides meaningful diagnostic support in selected sessile serrated ...
Valentina Angerilli, M. Elisa Vink‐Börger, Nanette S. van Roermund, Gesina van Lijnschoten, Chantal C.H.J. Kuijpers, Nicole C.T. van Grieken, Matteo Fassan, Joep E. Ijspeert, Rachel S. van der Post, Iris D. Nagtegaal   +9 more
wiley   +1 more source

Macronutrient concentrations in human milk beyond the first half year of lactation: a cohort study. [PDF]

Arch Dis Child Fetal Neonatal Ed
Muts J, Lukowski JIA, Twisk JWR, Schoonderwoerd A, van Goudoever JB, van Keulen BJ, Van Den Akker CHP.   +6 more
europepmc   +1 more source

Bibliography and archival guide to the national archives at the Hague (The Netherlands) / Jos Gommans, Lennart Bes, Gijs Kruijtzer

openalex   +1 more source

The impact of accumulating immune adaptation in circulating strains of HIV‐1

HIV Medicine, EarlyView.
Abstract Background Mutations in human immunodeficiency virus type 1 (HIV‐1) enable the virus to evade recognition and killing by human leucocyte antigen (HLA)‐restricted T cells. These viral adaptations are specific to the HLA type of individuals and are therefore evident as HLA allele‐HIV sequence associations at the population level. Most studies of
Marwah Al‐kaabi, Alison Castley, Pooja Deshpande, Abha Chopra, David Nolan, Simon Mallal, Mina John, Silvana Gaudieri   +7 more
wiley   +1 more source

How to ensure effective and sustainable ILI surveillance in Belgian general practices? : protocol. [PDF]

Arch Public Health
Nahimana M, Bensemmane S, Rouvez F, Debouverie L, Moreels S, De Schreye R, Bossuyt N.   +6 more
europepmc   +1 more source