Results 51 to 60 of about 219,728 (265)
British Journal of Clinical Pharmacology, EarlyView.Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden +3 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Background Thiopurines are used to maintain remission in inflammatory bowel disease (IBD). These drugs are metabolized into 6‐thioguanine nucleotides (6‐TGN), associated with efficacy, and 6‐methylmercaptopurine ribonucleotides (6‐MMPR), associated with adverse drug reactions. Pregnancy has been linked to a shift in thiopurine metabolism, characterized
Dianne G. Bouwknegt +13 more
wiley +1 more source
The rediscovery of the nineteenth-century exterior colours of the Vesting Naarden
Bulletin KNOB, 2019 In the former fortress town of Naarden, the exterior woodwork of the military buildings from both the seventeenth and nineteenth centuries is still painted in a dark shade of green known as ‘monumentengroen’.
Lenneke Willemstein
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aim To identify safety concerns reported by coroners following fentanyl patch‐related deaths in England, Wales and Northern Ireland, and determine differences in coronial reporting. Methods A systematic case series linking the National Programme on Substance Use Mortality (NPSUM) and the Preventable Deaths Tracker (PDT) (https ...
Eman Mshari +2 more
wiley +1 more source
Cultural Heritage and the Public Domain
Liber Quarterly: The Journal of European Research Libraries, 2012 For centuries, libraries, archives and museums from across Europe have been the custodians of our rich and diverse cultural heritage. They have preserved and provided access to the testimonies of knowledge, beauty and imagination, such as sculptures ...
Bas Savenije, Annemarie Beunen
doaj +1 more source
Extent, characteristics and policy applications of Key Biodiversity Areas
Biological Reviews, EarlyView.ABSTRACT A global standard for the identification of Key Biodiversity Areas (KBAs) was published 10 years ago to provide a unified set of criteria for identifying ‘sites of significance for the global persistence of biodiversity’. We review the initiative's origins, the KBA identification process, characteristics of the current network, threats, policy
Stuart H. M. Butchart +57 more
wiley +1 more source
Airborne LiDAR for DEM generation: some critical issues [PDF]
, 2008 Airborne LiDAR is one of the most effective and reliable means of terrain data collection. Using LiDAR data for DEM generation is becoming a standard practice in spatial related areas.
Liu, Xiaoye
core +2 more sources
Business Strategy and the Environment, EarlyView.ABSTRACT Environmentally oriented ventures pursue a dual mission: to create both environmental and financial value. This dual mission adds complexity and can influence ventures' funding prospects, as investors mostly pursue financial motivations.
David Flore +2 more
wiley +1 more source
Radio Oranje: Enhanced Access to a Historical Spoken Word Collection [PDF]
, 2007 Access to historical audio collections is typically very restricted:\ud content is often only available on physical (analog) media and the\ud metadata is usually limited to keywords, giving access at the level\ud of relatively large fragments, e.g., an ...
Heeren, Willemijn +3 more
core +1 more source
Business Strategy and the Environment, EarlyView.ABSTRACT This paper examines the relationship between industrial robotics adoption and ecological capacity, measured by biocapacity, using panel data from 50 countries over the period 2000–2024. We investigate the transmission mechanisms, non‐linearities, spatial spillovers, and heterogeneity characterizing this relationship.
Brahim Bergougui +1 more
wiley +1 more source