Results 121 to 130 of about 373,386 (221)

“It Takes a (Healthy) Village to Raise a Child:” A Case for Integrating Public Health and Social Work Research to Eliminate Health Disparities [PDF]

, 2017
Issue Editor, Heather H.
Goltz, Heather H
core   +1 more source

NCI-MATCH Arms N & P: Phase II study of PI3K beta inhibitor GSK2636771 in patients (pts) with cancers (ca) with PTEN mutation/deletion (mut/del) or PTEN protein loss [PDF]

, 2018
Background: The NCI-MATCH trial is the largest national study (1173 sites) for ptswith relapsed/ refractory solid tumors, lymphomas and myeloma, which assigns tar-geted therapies based on individual tumor molecular alterations detected using theadapted ...
Arteaga, C., Chen, A. P., Conley, B. A., Doyle, L. A., Flaherty, K. T., Hamilton, S. R., Harris, L. N., Janku, F., Jegede, O., Konstantinopoulos, P., Li, S., McShane, L. M., Meric-Bernstam, F., Mitchell, E. P, O\u27Dwyer, P. J., Patton, D., Puhalla, S. L., Rubinstein, L. V., Williams, P. M., Zwiebel, J. A.   +19 more
core   +1 more source

p53-induced RNA-binding protein ZMAT3 inhibits transcription of a hexokinase to suppress mitochondrial respiration in human cancer cells

eLife
The tumor suppressor p53 is a transcription factor that controls the expression of hundreds of genes. Emerging evidence indicates that the p53-induced RNA-binding protein ZMAT3 acts as a key splicing regulator that contributes to p53-dependent tumor ...
Ravi Kumar, Simon Couly, Bruna R Muys, Xiao Ling Li, Ioannis Grammatikakis, Ragini Singh, Mary Guest, Xinyu Wen, Wei Tang, Stefan Ambs, Lisa M Jenkins, Erica C Pehrsson, Raj Chari, Tsung-Ping Su, Ashish Lal   +14 more
doaj   +1 more source

The role of the research sector in ABS governance [PDF]

, 2007
The aims of this paper are to examine the renewed role of the academic sector in the innovation chain, starting from traditional knowledge and wild genetic resources and ending with a final product marketed by bio-industries; to identify changes in the ...
Brahy, Nicolas, Louafi, Selim
core  

Protocol for establishing liver tumors via ultrasound-guided intrahepatic injection prior partial hepatic resection in a mouse model

STAR Protocols
Summary: We present a protocol to generate a liver tumor murine model utilizing orthotopic ultrasound-guided intrahepatic injections of tumor cells and a partial hepatectomy.
Shadin Ghabra, Rajiv Trehan, Francisco Rodriguez-Matos, Chi Ma, Tim F. Greten   +4 more
doaj   +1 more source

Make It Your Own Clinical Trials Posters: A Regional Collaboration with the National Cancer Institute [PDF]

, 2010
University of Kansas Medical Center - Midwest Cancer Institute Poster SessionIntroduction: National health organizations usually offer a limited variety of publication resources to the regional organizations that they serve.
Brown, Melissa, Casey, Christopher, Groneman, Brooke, Krebill, Hope, Kreuter, Matthew W., Pfeiffer, Debbie   +5 more
core  

Medical Countermeasures for Radiation Induced Health Effects: Reports of an Interagency Panel Session Held at the NASA Human Research Program Investigator's Workshop, January 26, 2017 [PDF]

An Interagency Panel Session organized by the NASA Human Research Program Space Radiation Program Element (SRPE) was held during the NASA Human Research Program (HRP) Investigators Workshop (IWS) in Galveston, Texas on January 26, 2017 to identify ...
Carnell, Lisa S., Homer, Mary, Hoots, Keith, Meeks, Heather, Prasanna, Pataje G. S., Rios, Carmen, Simonsen, Lisa C., Taliaferro, Lanyn, Wathen, Lynne K.   +8 more
core   +1 more source

The characterization, management, and future considerations for ErbB-family TKI-associated diarrhea. [PDF]

, 2019
PurposeDiarrhea is recognized as a common adverse event associated with tyrosine kinase inhibitors (TKIs), with those targeting the ErbB family of receptors being associated with the highest rate of diarrhea.MethodsThis paper reviews data on the ...
Bosserman, Linda, Bryce, Richard, Di Palma, Jack A, Moran, Susan, Olek, Elizabeth, Rugo, Hope S, Tripathy, Debu   +6 more
core  

P1.01-12 Trends in the National Cancer Institute (NCI) Sponsored Lung Cancer Clinical Trials Pre and Post NCI’s National Clinical Trials Network (NCTN) [PDF]

Journal of Thoracic Oncology, 2019
S. Malik, G. Mishkin, A. Denicoff, J. Zhao, E. Korn, M. Mooney   +5 more
openaire   +1 more source

Longitudinal liquid biopsy identifies an early predictive biomarker of immune checkpoint blockade response in head and neck squamous cell carcinoma

Nature Communications
Immune checkpoint blockade (ICB) has improved outcomes for patients with head and neck squamous cell carcinoma (HNSCC), but predictive biomarkers remain limited.
Binbin Wang, Robert Saddawi-Konefka, Lauren M. Clubb, Shiqi Tang, Di Wu, Sumit Mukherjee, Sahil Sahni, Saugato Rahman Dhruba, Xinping Yang, Sumeet Patiyal, Chi-Ping Day, Parth A. Desai, Clint Allen, Kun Wang, J. Silvio Gutkind, Eytan Ruppin   +15 more
doaj   +1 more source