Results 161 to 170 of about 884,783 (299)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

NCI-Designated Cancer Centers' Policies and Practices with regard to Alcohol and Cancer: A Call to Lead. [PDF]

Cancer Epidemiol Biomarkers Prev
Hawk ET, Martch SL, Si M, Shete S.
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Erratum for Kweon et al., “Substrate Specificity and Structural Characteristics of the Novel Rieske Nonheme Iron Aromatic Ring-Hydroxylating Oxygenases NidAB and NidA3B3 from Mycobacterium vanbaalenii PYR-1”

mBio, 2020
Ohgew Kweon, Seong-Jae Kim, James P. Freeman, Jaekyeong Song, Songjoon Baek, Carl E. Cerniglia   +5 more
doaj   +1 more source

Breast cancer survivors' perspectives on a clinical decision tool to support individualized exercise prescriptions and discussions. [PDF]

Support Care Cancer
Wilson OWA, Wojcik KM, Kerr EM, Rivera I, Tian E, Schneider JD, Brick R, Berrigan D, Tamura K, Rogers LQ, Demark-Wahnefried W, Street RL, Jayasekera J.   +12 more
europepmc   +1 more source

Community Recommendations for Enhanced Regional Survivorship Outcomes: A Case for Social and Structural Determinants of Health from a U.S. National Cancer Institute (NCI) Designated Cancer Center

Journal of Health Research, 2023
Marcie S. Wright, Alisa E. Brewer, Matthew Wells, Michael A. Preston, Maria D. Thomson, Vanessa B. Sheppard   +5 more
openaire   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

When Did the Term "Translational Research" Emerge-and Why? [PDF]

J Korean Med Sci
Jeon JH.
europepmc   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

The new vision from the National Institute of Allergy and Infectious Diseases (NIAID). [PDF]

Nat Med
Taubenberger JK, Powers JH, Bhattacharya J.   +2 more
europepmc   +1 more source