Results 171 to 180 of about 884,783 (299)

Autografts in Psoriasis**From the Dermatology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20014. Public Health Service, U.S. Department of Health, Education, and Welfare.

Journal of Investigative Dermatology, 1965
Clendenning, William E., van Scott, Eugene J.   +1 more
openaire   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Pregnancy-associated cancer death in the United States, 2018-2023. [PDF]

Oncologist
Chen Y, Molina G, Zhang T, Furman LM, Abnet CC, Molina RL.   +5 more
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

A Computational Pathology Model to Predict Docetaxel Benefit in Localized High-Risk and Metastatic Prostate Cancer. [PDF]

Clin Cancer Res
Medina S, Tokuyama N, Hammouda K, Pathak T, Mirtti T, Fu P, Gupta S, Lal P, Sandler HM, Correa R, Chafe S, Shah A, Efstathiou JA, Hoffman K, Straza M, Hallman MA, Jordan R, Pugh SL, Sweeney CJ, Madabhushi A.   +19 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Different diabetes types and pancreatic ductal adenocarcinoma: a Mendelian randomization and pathway/gene-set analysis. [PDF]

J Natl Cancer Inst
Zhang T, Hua X, Mohindroo C, Wang X, Dutta D, Liu J, Katta S, Li SA, Wang J, Antwi SO, Arslan AA, Beane Freeman LE, Bracci PM, Canzian F, Du M, Gallinger S, Goodman PJ, Katzke V, Kooperberg C, Le Marchand L, Neale RE, Patel AV, Perdomo S, Shu XO, Visvanathan K, Van Den Eeden SK, White E, Zheng W, Albanes D, Andreotti G, Bamlet WR, Brennan P, Buring JE, Chanock SJ, Chen Y, Darst B, Ferrari P, Giovannucci EL, Goggins M, Haiman C, Hassan M, Holly EA, Hung RJ, Jones MR, Kraft P, Kurtz RC, Malats N, Moore SC, Ng K, Oberg AL, Orlow I, Peters U, Porta M, Rabe KG, Rothman N, Sánchez MJ, Sesso HD, Silverman DT, Southey MC, Um CY, Yarmolinsky J, Yu H, Yuan C, Zhong J, Wolpin BM, Risch HA, Amundadottir LT, Klein AP, Yu K, Zhang H, Stolzenberg-Solomon RZ.   +70 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

A novel analysis methodology for assessment of re-identification risks for the National Cancer Institute cancer registry privacy preserving record linkage technique. [PDF]

J Am Med Inform Assoc
Kantarcioglu M, Howe W, Liu B, Petkov V, Casas-Silva E, Velasquez-Kolnik D, Malin BA, Penberthy L.   +7 more
europepmc   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source