Results 181 to 190 of about 884,783 (299)

Clinical and dosimetric dataset of time-to-event normal tissue complication probability for osteoradionecrosis. [PDF]

Sci Data
West NA, Kamel S, Wentzel A, Kaffey Z, Abdelaal M, Elisabeta Marai G, Canahuate G, Zhang X, Chen MM, Wahid KA, Rigert J, Brock KK, Chambers M, Otun AO, Aponte-Wesson R, He R, Naser MA, Hutcheson KA, Mohamed ASR, van Dijk LV, Moreno AC, Lai SY, Fuller CD, Humbert-Vidan L.   +23 more
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Investigating the Causal Effect of Potential Therapeutic Agents for Colorectal Cancer Prevention: A Mendelian Randomization Analysis. [PDF]

Cancer Epidemiol Biomarkers Prev
Fryer E, Bishop DT, Campbell PT, Chan AT, Le Marchand L, Li CI, Moreno V, Gunter MJ, Phipps AI, Grant RC, Schmit SL, Martin RM, Yarmolinsky J, Haycock P.   +13 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Improved polygenic risk prediction models for breast cancer subtypes in women of African ancestry. [PDF]

Nat Genet
Li JL, Zhang H, Wang X, Jia G, McClellan JC, Guo W, Sun Y, Fiorica PN, Ambs S, Barnard ME, Chen Y, Garcia-Closas M, Gu J, Hu JJ, John EM, Nathanson KL, Nemesure B, Pal T, Shu XO, Press MF, Sanderson M, Sandler DP, Troester MA, Yao S, Long J, Ahearn TU, Brewster AM, Falusi A, Kraft P, Hennis AJM, Makumbi T, Mapoko BSE, O'Brien KM, Ojengbede O, Olshan AF, Reid S, Zirpoli G, Cai Q, Butler EN, Huang M, Obafunwa J, Weinberg CR, Ambrosone C, Ping J, Tao R, Li B, Guo X, Gao G, Conti DV, Chatterjee N, Palmer JR, Olopade OI, Zheng W, Haiman CA, Huo D.   +54 more
europepmc   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Autoradiographic Analysis of Turnover Times of Normal and Psoriatic Epidermis**From the Dermatology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland. Public Health Service, U.S. Department of Health, Education and Welfare.

Journal of Investigative Dermatology, 1965
Weinstein, Gerald D., van Scott, Eugene J.   +1 more
openaire   +2 more sources

Obesity and breast density enhance immune exclusion in the primary tumor microenvironment and promote breast cancer metastasis. [PDF]

Oncogene
Williams AE, Hoffmann EJ, Inman DR, Gari MK, Zhou C, Burkel BM, Haidar N, Pan Y, Halambeck M, Moore BN, Wisinski KB, McGregor SM, Kerr SC, Arendt LM, Ponik SM.   +14 more
europepmc   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Assessment of Rebound in Cancer Diagnoses in California in 2022, by Stage, Sociodemographic Factors, and Rurality. [PDF]

Cancer Epidemiol Biomarkers Prev
Van Blarigan EL, Canchola AJ, Zhu L, Shariff-Marco S, DeRouen MC, Cheng I, McKinley M, Oh DL, Lin K, Gomez SL.   +9 more
europepmc   +1 more source