Results 131 to 140 of about 2,328,556 (303)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Child welfare worker perspectives on documentation and case recording practices in Canada: A mixed-methods study protocol.

PLoS ONE
In health care and child welfare, clinical records and case notes serve multiple functions. When records are aggregated and processed to create administrative data, they can be analyzed and used to inform policy development and decision-making.
Nathaniel J Pollock, Cassandra Yantha, Lil Tonmyr, Kimberly Jewers-Dailley, Melody E Morton Ninomiya   +4 more
doaj   +1 more source

Applying Ragin's Crisp and Fuzzy Set QCA to Large Datasets: Social Class and Educational Achievement in the National Child Development Study [PDF]

The paper explores the use of Charles Ragin's Qualitative Comparative Analysis (QCA) in both its crisp and fuzzy set versions in the study of the relations between social class origin, sex, 'ability' and subsequent educational achievement.
Barry Cooper
core  

Assessing recall of early life circumstances: evidence from the National Child Development Study

Longitudinal and Life Course Studies, 2014
Cross-sectional studies and longitudinal studies alike make regular use of retrospective questions about childhood circumstances. However, little is known about the accuracy with which adults can recall this kind of information. This paper seeks to address this topic by comparing retrospective reports of the number of people and the number of rooms in ...
openaire   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

A National Study of Child Development (NCDS 1958 cohort) [PDF]

Proceedings of the Royal Society of Medicine, 1973
openaire   +4 more sources

Large Language Models for Epidemiological Research via Automated Machine Learning: Case Study Using Data From the British National Child Development Study.

JMIR Med Inform, 2023
Wibaek R, Andersen GS, Dahm CC, Witte DR, Hulman A.   +4 more
europepmc   +1 more source

Child Development and Success or Failure in the Youth Labour Market [PDF]

In this paper we examine the relationship between childhood factors and subsequent economic and social success or failure as an adult. Unlike many studies which typically have little data on pre-labour market factors (other than schooling or in fewer ...
Paul Gregg, Stephen Machin
core  

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source