Results 91 to 100 of about 1,641,247 (266)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Stylistics and national culture

Russian journal of linguistics: Vestnik RUDN, 2011
The article analyses the interconnection of national culture and some expressive stylistic means used in works by Mario Vargas Llosa.
E V Zhuravliova
doaj  

Stock markets' reaction to Covid-19: Moderating role of national culture. [PDF]

Financ Res Lett, 2021
Ashraf BN.
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Lutsk in the interwar period: Features of the Ukrainian educational process and educational institutions

Науковий вісник Чернівецького національного університету імені Юрія Федьковича. Історія, 2022
Scientific research is devoted to an interesting and multifaceted problem of regional history: the study of the peculiarities of the Ukrainian educational process of educational institutions in Lutsk, which in the period between the two world wars was ...
Людмила Стрільчук
doaj  

Corporate immunity, national culture and stock returns: Startups amid the COVID-19 pandemic. [PDF]

Int Rev Financ Anal, 2022
Hoang HV, Nguyen C, Nguyen DK.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

National Culture and Culinary Exploration: Japan Evidence of Heterogenous Moderating Roles of Social Facilitation. [PDF]

Front Psychol, 2021
Liu B, Wang Y, Katsumata S, Li Y, Gao W, Li X.   +5 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Examining the Relationship between Mindfulness, Personality, and National Culture for Construction Safety. [PDF]

Int J Environ Res Public Health, 2021
Solomon T, Esmaeili B.
europepmc   +1 more source