Results 121 to 130 of about 5,004,752 (309)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Pleasure, profit and pain: Alcohol in New Zealand and the contemporary culture of intoxication [PDF]

open access: yes, 2013
This book details the rich, complex and often contested role of alcohol in New Zealand society. It explores the three fundamental alcohol rights that continue to fight for dominance of the national drinking culture: the rights of individual drinkers to ...
Campbell, Maxine M.   +3 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Stylistics and national culture

open access: yesRussian journal of linguistics: Vestnik RUDN, 2011
The article analyses the interconnection of national culture and some expressive stylistic means used in works by Mario Vargas Llosa.
E V Zhuravliova
doaj  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Ukrainian Archaeological Opera Chornobyldorf in the Context of the Development of the Opera Aperta Genre and Modern Musical-Performative Experiments

open access: yesКультура і мистецтво у сучасному світі
The aim of the article is to interpret the musical dramaturgy of the Ukrainian archaeological opera Chornobyldorf in the context of the development of the opera aperta genre and musical-performative experiments from the late 20th to the first quarter of
Andrii Furdychko   +3 more
doaj   +1 more source

The impact of national culture on e-government implementation: A comparison case study [PDF]

open access: yes, 2009
Over the past decade there has been increasing interest in the IS research literature on the impact of cultural differences on the development and use of information and communications technologies (Ives & Jarvenpaa, 1991; Shore & Venkatachalam, 1995 ...
Ali, M, El-Haddadeh, R, Weerakkody, V
core   +1 more source

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