Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Are National and Organizational Cultures Isomorphic? Evidence from a Four Country Comparative Study [PDF]
This pilot study investigates whether organizational practices as observed through differing organizational cultures systematically replicate or reject national values.
Rune Ellemose Gulev
core
Szu-Feng Chen, Assistant Professor, Department of Theatre and Dance, travels to Singapore [PDF]
, 2012 Professor Szu-Feng Chen was invited by The Theatre Practice (TTP) in Singapore to create set and costume design for Lao Jiu: The Musical, its feature musical production for the Singapore Kuo Pao Kun Festival.I was invited by The Theatre Practice (TTP) in
Chen, Szu-Feng
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Government policies, national culture and social distancing during the first wave of the COVID-19 pandemic: International evidence. [PDF]
Saf Sci, 2021 Wang Y.
europepmc +1 more source
On the Myth of a General National Culture. Making Visible Specific Cultural Characteristics of Learners in Different\ud Educational Contexts [PDF]
, 2012 The concept of a few values that can characteristically explain all units of culture (Schneider, 1968, pp.1-2) within any national context generally sounds promising. In order to take design-oriented decisions on culture-specific research questions, such
Adelsberger, Heimo H., Richter, Thomas
core
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Changing Practice in a National Legal Deposit Library [PDF]
, 2006 This two-part essay considers how digital culture has influenced ideas about permanence and looks at the change in collecting practice in a legal deposit library.
Mason, Ingrid
core
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source